GLP-1 Receptor Agonist Use in Wolfram Syndrome Shows No Glycemic or BMI Benefit, Common GI Effects
Can diabetes drugs help Wolfram syndrome? A new study looks at real-world use.
A retrospective cohort study of 84 participants with genetically confirmed Wolfram syndrome and insulin-dependent diabetes found 35% had rec…
Doctors prescribed diabetes drugs to 35% of rare Wolfram syndrome patients, but records show no improvement in blood sugar, weight, or slowi…
Lipoprotein(a) shows substantial longitudinal variability in children with type 1 diabetes
Does a child's heart risk marker change over time? New study finds surprising variability.
A retrospective single-center cohort study of 287 children and adolescents with type 1 diabetes found that 32% exhibited intraindividual Lp(…
A child's heart risk marker can swing wildly over time, with nearly 12% of kids crossing a key danger threshold during just six years of mon…
Horseshoe-like plantar hyperkeratosis associated with prediabetes in overweight adults
Could a specific foot skin change be a visible clue for prediabetes?
A cross-sectional cohort study of 191 adults with overweight or obesity found horseshoe-like plantar hyperkeratosis (HSLPH) was more frequen…
A horseshoe-shaped patch of thickened skin on the foot is a strong visual clue for prediabetes in adults with overweight or obesity.
Polypharmacy and age predict MACE in rural Montana type 2 diabetes cohort
In rural diabetes care, does taking more medications signal higher heart risk?
An observational cohort study of 591 type 2 diabetes patients in rural Montana found medication count and age were significant predictors of…
In rural Montana, patients with type 2 diabetes taking more medications faced higher risks of heart attacks, strokes, and kidney or nerve da…
High body roundness index associated with higher odds of prevalent stroke in Chinese adults
Could a simple waist measurement help spot stroke risk in your community?
A cross-sectional study of 6,858 adults in a Chinese community screening program found high body roundness index (BRI ≥4.6) was associated w…
A simple waist measurement called the Body Roundness Index may help spot stroke risk in community screenings, though it works best alongside…
Tubeless automated insulin delivery reduces HbA1c more than multiple daily injections in type 1 diabetes
Tubeless insulin pump system helps lower blood sugar better than injections in study
A 13-week randomized controlled trial in 188 children and adults with type 1 diabetes and elevated HbA1c found that tubeless automated insul…
A tubeless insulin pump system lowered average blood sugar better than injections for people with type 1 diabetes in a new study.
Lixisenatide shows no effect on arterial stiffness in type 2 diabetes with chronic kidney disease
Study finds diabetes drug lixisenatide did not improve artery stiffness in kidney disease patients
A single-center, proof-of-concept randomized controlled trial in 90 people with type 2 diabetes and chronic kidney disease found that 24 wee…
A diabetes drug did not soften arteries in people with kidney disease, showing no improvement in a key heart risk factor after 24 weeks of t…
Post hoc analysis links WHtR threshold to remission in obesity management with tirzepatide vs semaglutide
Could hitting specific weight targets help people feel better?
A post hoc analysis of the SURMOUNT-5 trial in participants with obesity found that 23.1%-33.9% on tirzepatide and 14.2%-20.7% on semaglutid…
People on tirzepatide who hit a waist-to-height ratio under 0.53 had more than double the odds of reaching remission compared to those who d…
Pilot qualitative study explores pathways and acceptability of cash transfers for low-income patients with hypertension or diabetes
Could giving cash to patients with high blood pressure or diabetes help their health?
A pilot RCT qualitative sub-study of 100 low-income Pennsylvania Medicaid patients with hypertension or diabetes explored an unconditional c…
Giving cash to low-income patients with high blood pressure or diabetes helped them cover basic needs, reducing stress and making it easier …
Phase 2 trial proposes 129XeMRI and RNA sequencing to study airway remodeling in obese asthma
Can a new type of lung scan reveal why asthma hits obese people harder?
A Phase 2 clinical trial proposal aims to use hyperpolarized 129XeMRI and single-cell RNA sequencing to investigate mechanisms of regional a…
A new lung scan maps hidden scarring in obese asthma patients, helping explain why these breathing problems are harder to treat than in othe…
Structured exercise program improves glycemic control and fitness in Bangladeshi adults with type 2 diabetes
Can six weeks of guided exercise help manage diabetes better than medication alone?
A 6-week RCT in 90 Bangladeshi adults with type 2 diabetes found that adding a physiotherapist-led exercise program to medication improved c…
Six weeks of guided exercise alongside medication improved blood sugar, walking distance, and quality of life for adults with type 2 diabete…
Walking program improves liver enzymes and BMI in children with PKU and NAFLD
Walking program shows improvement in liver health markers for children with PKU and fatty liver
An 8-week RCT in 40 overweight/obese children with PKU and NAFLD found that a free walking program significantly improved BMI, ALT, GGT, ALP…
An 8-week walking program improved liver health markers and BMI in children with PKU and fatty liver disease.