SBSPON gene variant rs2291219 linked to higher T2DM risk in Northwest Indian population
A Hidden Gene May Be Quietly Raising Your Type 2 Diabetes Risk
A case-control candidate gene association study in a Northwest Indian population found SBSPON gene expression was significantly higher in in…
A hidden gene linked to higher type 2 diabetes risk may also be shortening the protective caps on DNA inside immune cells, signaling faster …
Three-parameter online nomogram predicts diabetic retinopathy risk in community-dwelling type 2 diabetes patients
Three Numbers Could Tell Your Doctor If Your Eyes Are at Risk
This retrospective cohort study evaluated a three-parameter online nomogram using diabetes duration, HbA1c, and high BMI (≥24 kg/m²) to pred…
A free, web-based calculator using only your diabetes duration, blood sugar control, and BMI could help doctors spot who needs an urgent eye…
Efgartigimod showed higher independent walking at week 4 and running at week 12 versus IVIG in GBS patients unable to walk
A Newer Drug Outperformed the Standard Treatment for a Paralyzing Nerve Disease
This single-center retrospective study evaluated efgartigimod versus intravenous immunoglobulin (IVIG) in 34 Guillain-Barré syndrome patient…
A newer drug helped 100% of paralyzed Guillain-Barré patients walk again in four weeks, outperforming the standard treatment in a recent stu…
Observational MRI study links impaired hypoglycemia awareness to blunted cerebral blood flow responses in type 1 diabetes
Type 1 Diabetes Rewires How the Brain Responds to Low Blood Sugar
This observational study used hyperinsulinemic clamp with arterial spin-labeling MRI to compare cerebral blood flow responses to hypoglycemi…
Type 1 diabetes changes how the brain handles low blood sugar, and those who can't feel the danger show the most severe disruption in brain …
Phase 4 study of evolocumab safety and tolerability in renal transplant recipients
Can a new cholesterol drug help kidney transplant patients without causing harm?
This Phase 4 study evaluated the safety and tolerability of evolocumab, a PCSK-9 inhibitor, in renal transplant recipients at three hospital…
A new cholesterol injection kept kidney transplant patients safe for over two years without serious side effects, offering a potential alter…
Bayesian network meta-analysis evaluates antidiabetic medications and dementia risk in 4,382,897 patients
Could diabetes drugs lower dementia risk, or raise it for some patients?
This Bayesian network meta-analysis synthesized data from 28 articles involving 4,382,897 patients to assess antidiabetic drugs and dementia…
Insulin and metformin cut dementia risk, but DPP4 inhibitors may double Alzheimer's risk compared to SGLT2 drugs in diabetes patients.
Hypothesis links cumulative levodopa exposure to frailty and reduced healthspan in Parkinson's disease
Researchers propose cumulative levodopa exposure may increase health complications in Parkinson’s disease
A hypothesis proposes that cumulative levodopa exposure in patients with Parkinson's disease may contribute to frailty and reduced healthspa…
Parkinson's patients on long-term levodopa face higher risks of dementia, falls, and death, echoing how other life-saving drugs later showed…
Cadonilimab therapy in cervical cancer associated with new-onset type 1 diabetes and diabetic ketoacidosis in a case report
A Cancer Drug Triggered Sudden Diabetes in an 81-Year-Old
This systematic review includes a case report of an 81-year-old female with cervical squamous cell carcinoma who developed diabetic ketoacid…
A powerful cancer drug can switch off the body's insulin supply almost overnight, causing sudden, life-threatening diabetes in patients with…
Body roundness index shows significant association with metabolic syndrome but constrained predictive ability for other CKM outcomes
A Simple Body Measurement May Reveal Your Hidden Health Risk
This systematic review and meta-analysis of 93 observational studies from 13 countries evaluated the body roundness index (BRI) against conv…
A simple math formula using your height and waist size may help doctors catch silent health problems long before they turn serious.
Meta-analysis finds machine learning models predict depression in diabetes with AUC 0.822
Can computer models predict diabetes depression risk better than usual guesses?
This systematic review and meta-analysis evaluated machine learning-based risk predictive models for depression in patients with diabetes me…
Computer models predict diabetes depression risk well in tests, but experts warn they are not ready for doctors to use on patients yet.
Review of mineralocorticoid receptor antagonists and aldosterone synthase inhibitors for primary aldosteronism
High Blood Pressure Isn't the Only Danger
This narrative review examines the use of mineralocorticoid receptor antagonists and aldosterone synthase inhibitors in patients with primar…
Controlling your blood pressure is not enough to protect your heart if you have this specific type of high blood pressure.
Review of 88 cases supports endoscopic resection for neurohypophyseal granular cell tumors
Rare Brain Tumor Found Near Pituitary Gland
This case report and review synthesizes data from 88 published cases plus one additional case report involving neurohypophyseal granular cel…
A rare brain tumor that hides near your pituitary gland can be removed with surgery, but you must stay on top of long-term monitoring.