Fixed-duration subcutaneous mosunetuzumab shows favorable efficacy and safety versus IV in relapsed follicular lymphoma.
Subcutaneous Mosunetuzumab Shows Promise for Follicular Lymphoma Patients
This Phase 2 primary analysis evaluated fixed-duration subcutaneous mosunetuzumab versus mosunetuzumab IV in patients with relapsed or refra…
A Phase 2 trial found subcutaneous mosunetuzumab had lower rates of severe side effects than the IV version for treating follicular lymphoma…
Meta-analysis links perinatal factors to childhood acute leukemia risk
Perinatal factors linked to higher leukemia risk in children
This systematic review and meta-analysis of 85 studies examined perinatal factors and childhood acute leukemia risk. High birth weight, mate…
A large analysis of 85 studies finds links between birth weight, maternal history, and cesarean sections with childhood leukemia risk.
Meta-analysis links maternal infection in pregnancy to childhood ALL risk
Maternal Infections During Pregnancy Linked to Higher Risk of Childhood Leukemia
This systematic review and meta-analysis of 26 studies found a modest association between maternal infection during pregnancy and childhood …
A large review of 26 studies found that maternal infections during pregnancy are associated with an increased risk of acute lymphoblastic le…
Systematic Review Links Lysosomal Pathways to Autoimmune Kidney Disease Progression
Lysosomal pathways may control autoimmune kidney disease progression
This systematic review synthesizes evidence that lysosomal functions act as checkpoints in autoimmune kidney diseases like lupus nephritis a…
New evidence suggests that targeting lysosomal functions could offer a new way to manage serious autoimmune kidney diseases.
Longitudinal TCR profiling predicts EBV, CMV, and GVHD in 108 allo-HSCT recipients
TCR Monitoring Predicts Dangerous Complications Before They Start
This longitudinal cohort study evaluated TCR beta repertoire profiling in 108 allogeneic hematopoietic stem cell transplantation recipients …
A new scan of immune cells can predict dangerous post-transplant complications weeks before symptoms appear.
Eight-gene signature associated with survival in patients with Diffuse Large B-cell lymphoma
Doctors find a new way to predict who needs stronger cancer care sooner
In this cohort study, a predictive signature based on the reactivation of eight normally silent tissue-dependent genes was identified in pat…
A new blood test can spot dangerous lymphoma risks early so doctors can change treatment plans before patients get sicker.
Meta-analysis associates emerging lesions after lutetium-177 therapy with worse overall survival in mCRPC
Emerging lesions on scans linked to lower survival in prostate cancer patients
This systematic review and meta-analysis evaluated interim post-treatment SPECT/CT findings in 648 patients with metastatic castration-resis…
New spots appearing on scans after treatment for advanced prostate cancer are linked to significantly lower survival rates.
Eltrombopag monotherapy assessed in moderate aplastic anemia and unilineage bone marrow failure disorders.
Oral Drug May Reduce Need for Frequent Blood Transfusions
This Phase 2 trial evaluated eltrombopag by mouth once a day in 34 people at least 2 years of age with moderate aplastic anemia or unilineag…
A new oral medication offers hope for patients who rely on regular blood transfusions.
Systematic review suggests partial glossectomy with speech therapy improves speech retention and reduces costs for oral cancer patients.
Partial glossectomy with speech therapy offers better speech recovery for oral cancer patients.
This systematic review synthesizes evidence regarding interventions for oral cancer patients, focusing on speech retention, mental health, a…
For oral cancer patients, early-stage partial surgery combined with speech therapy may improve speech recovery and lower costs compared to l…
Three Biomarkers Show High Diagnostic Accuracy for Ulcerative Colitis in Cohort Study
Three biomarkers show promise for diagnosing ulcerative colitis
This cohort study evaluated ARHGEF3, S100A8, and RHOU as diagnostic biomarkers for ulcerative colitis. A nomogram achieved AUCs of 0.991 in …
A new study identifies three biomarkers that may help diagnose ulcerative colitis and distinguish it from Crohn's disease.
Narrative review discusses sarcopenia and intramuscular vaccination immune landscape gaps
Understanding muscle immunity helps improve vaccines for people with sarcopenia.
This narrative review examines the intersection of sarcopenia and intramuscular vaccination. The authors highlight significant gaps in under…
We still do not fully understand how muscle immunity changes in health and disease, which makes it hard to predict vaccine responses in peop…
Scoping review of wastewater-based surveillance for AMR and SARS-CoV-2 in GCC countries
Wastewater Tests Could Save Lives Across the Gulf
This scoping review and questionnaire survey examined 26 studies on wastewater-based surveillance (WBS) for microbial pathogens in GCC count…
Imagine walking down a busy street. You can hear the noise of cars and people.