Meta-analysis finds no mortality difference between CA and CT for drug-resistant P. aeruginosa infections
Which antibiotic works better for dangerous drug-resistant infections?
A meta-analysis of 10 observational studies including 1409 patients with drug-resistant P. aeruginosa infections found no significant differ…
Two powerful new antibiotics show equal survival rates for patients fighting dangerous, drug-resistant infections.
Review finds probiotic-mast cell interplay in gut inflammation remains poorly defined
Review finds limited understanding of how probiotics interact with gut cells in inflammation
A systematic mini-review synthesizing existing evidence found the functional interplay between probiotics and mast cells in gut health and d…
Probiotics and gut immune cells called mast cells might interact to influence inflammation in conditions like food allergies, but scientists…
Short-course antibiotics after appendectomy for complicated appendicitis show similar infection risk to long-course therapy
Short-course antibiotics after complicated appendectomy show similar infection risk to longer courses
A meta-analysis of 3251 patients from 4 RCTs and 9 observational studies found short-course antibiotic therapy (<3 days) after appendectomy …
Shorter antibiotics after complicated appendectomy carry similar infection risks to longer courses while often shortening hospital stays.
Meta-analysis finds no significant difference in outcomes between high- and low-dose ceftriaxone for non-CNS infections
Do higher doses of a common antibiotic help adults with infections?
A meta-analysis of eight studies involving 5145 adults with non-CNS infections found no statistically significant difference in clinical cur…
Higher doses of the antibiotic ceftriaxone show no clear benefit over the standard 1-gram daily dose for curing infections in adults, based …
Meta-analysis finds 30.7% molecular prevalence of yellow fever virus in non-human primates
Yellow fever virus found in many monkeys in the Americas, study shows
A meta-analysis of 39 studies involving 7,183 non-human primates found pooled molecular prevalence of yellow fever virus infection was 30.7%…
Yellow fever virus was found in 31% of monkey samples and 43% of tissue tests, with infected animals in detailed cases all dying from severe…
Short-course antibiotic therapy shows comparable outcomes to extended courses in ICU patients with MDR Gram-negative infections
Can critically ill patients safely take shorter courses of powerful antibiotics?
A meta-analysis of 602 critically ill ICU patients found no significant difference in mortality or clinical failure between short-course (6-…
Critically ill patients with tough infections may safely take shorter antibiotic courses, though relapse risk warrants further study.
Network meta-analysis suggests Chinese patent medicines plus Western medicine may improve functional constipation in elderly
Chinese herbal medicines combined with Western drugs may help elderly constipation
A network meta-analysis of 23 RCTs involving 2065 elderly patients with functional constipation found that six Chinese patent medicines comb…
Adding specific Chinese herbal medicines to standard Western drugs may improve overall treatment response for elderly constipation, though e…
Review: New syphilis tests bridge diagnostic window but face standardization hurdles
New syphilis tests show promise for earlier detection but face standardization hurdles
A systematic review synthesizes evidence on technological innovations for syphilis diagnosis. Advanced nucleic acid amplification tests and …
New syphilis tests could detect infections earlier than traditional methods, but global standardization hurdles remain before they can be wi…
Engineered bacteriophage systems show potential framework for treating multidrug-resistant bacterial infections
Can engineered viruses help fight superbugs? A new review maps a path forward.
A systematic review discusses advances in engineered bacteriophage therapeutic systems for multidrug-resistant pathogens. The review outline…
Engineered viruses paired with advanced imaging offer a new way to fight dangerous superbugs that no longer respond to standard antibiotics.
Aphid-killing bacteria show diverse mechanisms for biological control of agricultural pests
Could bacteria from plants and aphids themselves help control these pests?
A systematic mini-review examines the potential of aphid-killing bacteria as biological control agents. It finds aphids are susceptible to d…
Farmers might soon fight destructive aphids using bacteria found on plants or inside the pests themselves, offering a sustainable alternativ…
Systematic review details metabolic adaptations of intracellular bacterial pathogens within host cells
How do bacteria hide inside our cells to survive and cause disease?
A systematic review synthesized evidence on how intracellular bacterial pathogens, including Listeria and Chlamydia species, employ sophisti…
Bacteria like Listeria and Chlamydia act as metabolic thieves, stealing nutrients from our cells to hide from our immune system and survive.
Systematic review maps gut microbiome–epigenetic crosstalk in obesity and type 2 diabetes
What's happening in your gut that might affect your weight and blood sugar?
A systematic review and bibliometric analysis of over 1,100 documents identified three major epigenetic domains involved in gut microbiome c…
Gut bacteria changes linked to obesity and type 2 diabetes may influence genetic switches, with research in this area growing nearly 28% ann…