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Oncology

1421 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Fissios App plus physiotherapy aims to cut postoperative complications in NSCLC surgery
Oncology RCT
Fissios App plus physiotherapy aims to cut postoperative complications in NSCLC surgery App may help lung cancer patients avoid complications after surgery
This randomized controlled trial protocol will enroll 560 NSCLC patients scheduled for surgery to test whether adding the Fissios App to fac…
A new trial will test if an app can help lung cancer patients avoid complications after surgery. Here's what's planned.
Symptomatic radiation necrosis occurs in 5.7% of intracranial brachytherapy patients
Oncology Meta-analysis
Symptomatic radiation necrosis occurs in 5.7% of intracranial brachytherapy patients Brachytherapy for brain tumors: 5.7% risk of radiation necrosis
This meta-analysis of 3666 patients undergoing intracranial brachytherapy for glioma, brain metastases, or meningioma found a pooled inciden…
About 1 in 18 patients who get internal radiation for brain tumors develop symptomatic radiation necrosis, a new analysis finds.
Serplulimab plus chemotherapy improves overall survival compared to chemotherapy alone in nsq-NSCLC
Oncology RCT
Serplulimab plus chemotherapy improves overall survival compared to chemotherapy alone in nsq-NSCLC Trial shows serplulimab improves survival in certain lung cancers
This Phase III randomized controlled trial of 636 treatment-naïve patients with locally advanced or metastatic nsq-NSCLC found that serpluli…
A new clinical trial shows that adding serplulimab to chemotherapy can extend life for patients with specific types of non-small cell lung c…
I-SPECT/CT shows high patient-level specificity of 0.95 for detecting residual disease in DTC
Oncology Meta-analysis
I-SPECT/CT shows high patient-level specificity of 0.95 for detecting residual disease in DTC Imaging technology shows promise for detecting thyroid cancer recurrence
This meta-analysis evaluates the diagnostic efficacy of I-SPECT/CT for identifying residual or recurrent disease in patients with differenti…
A new imaging method called I-SPECT/CT helps doctors find leftover or returning thyroid cancer cells with high accuracy after treatment.
Evaluating ctDNA Dynamics as Prognostic Biomarkers in Advanced HR+ HER2- Breast Cancer
Oncology Phase III
Evaluating ctDNA Dynamics as Prognostic Biomarkers in Advanced HR+ HER2- Breast Cancer Ribociclib and Letrozole Show Promise for Advanced Breast Cancer
This Phase IIIb trial evaluates how circulating tumor DNA (ctDNA) dynamics influence progression-free survival for patients treated with rib…
New data suggests that tracking specific genetic markers in the blood may help predict how well patients with advanced breast cancer respond…
DeSTIL-positive HER2+ breast cancer patients show HR 0.09 for event-free survival with trastuzumab
Oncology RCT
DeSTIL-positive HER2+ breast cancer patients show HR 0.09 for event-free survival with trastuzumab Trial Shows DeSTIL Signature Identifies Patients Benefiting From Trastuzumab
This Phase III randomized clinical trial evaluated the DeSTIL signature in a cohort of 221 validation patients and 250 training patients wit…
A new genetic marker called DeSTIL helps identify which HER2-positive breast cancer patients may see better outcomes when treated with trast…
Immunohistochemical profiling helps differentiate synchronous primary breast invasive carcinoma from metastatic ovarian carcinoma
Oncology Sys. Review
Immunohistochemical profiling helps differentiate synchronous primary breast invasive carcinoma from metastatic ovarian carcinoma One woman diagnosed with two different types of cancer simultaneously
This case report and literature review describes a patient with concurrent primary breast cancer and metastatic high-grade serous ovarian ca…
A rare case reveals how one patient can have both breast and ovarian cancer at once, highlighting a complex diagnostic challenge.
Hemithyroidectomy is associated with a 3% higher risk difference in cancer recurrence rate
Oncology Meta-analysis
Hemithyroidectomy is associated with a 3% higher risk difference in cancer recurrence rate Hemithyroidectomy linked to higher thyroid cancer recurrence
This meta-analysis of 98,604 patients with differentiated thyroid carcinoma found that hemithyroidectomy (HT) was associated with a 3% highe…
A large meta-analysis found that hemithyroidectomy for differentiated thyroid cancer has a higher recurrence rate than total thyroidectomy, …
HIFU ranks highest for fibroid volume reduction and hormonal stability in network meta-analysis
Oncology Sys. Review
HIFU ranks highest for fibroid volume reduction and hormonal stability in network meta-analysis High intensity focused ultrasound shows promise for uterine fibroids
This network meta-analysis of 2622 women with symptomatic uterine fibroids indicates that HIFU ranked highest for fibroid volume reduction, …
A review of 2,622 patients suggests high-intensity focused ultrasound is highly effective at shrinking fibroid size and preventing regrowth.
Anti-CD19 shRNA-engineered CAR-T cells achieve an 88% overall response rate in B-cell acute lymphoblastic leukemia
Oncology Meta-analysis
Anti-CD19 shRNA-engineered CAR-T cells achieve an 88% overall response rate in B-cell acute lymphoblastic leukemia CAR-T Cells Show Promise for B-cell Acute Lymphoblastic Leukemia
This meta-analysis evaluates anti-CD19 shRNA-engineered CAR-T cells (interleukin-6 knockdown) for patients with B-cell acute lymphoblastic l…
New research into modified CAR-T cells shows high response rates in patients with a specific type of leukemia while managing serious side ef…
Olanzapine significantly improves complete response and total control in chemotherapy-induced nausea for breast cancer
Oncology Meta-analysis
Olanzapine significantly improves complete response and total control in chemotherapy-induced nausea for breast cancer Olanzapine helps manage nausea in breast cancer chemotherapy
This meta-analysis of 4 studies involving 857 patients found that olanzapine with regular antiemetic treatment improved complete response (R…
Adding olanzapine to standard care can significantly improve nausea control and complete response for patients undergoing breast cancer chem…
Pseudoprogression in immune checkpoint inhibitor therapy is associated with modest tumor growth and early progression
Oncology Meta-analysis
Pseudoprogression in immune checkpoint inhibitor therapy is associated with modest tumor growth and early progression Immune Checkpoint Inhibitors May Cause Initial Tumor Growth in Cancer
This meta-analysis of retrospective data examines patients with solid tumors experiencing pseudoprogression during immune checkpoint inhibit…
A growing tumor during immunotherapy might actually be a sign that the treatment is working, not a sign that the cancer is spreading.