Narrative review discusses high-throughput screening technologies for adoptive T cell therapy optimization
Review of high-throughput screening technologies for adoptive T cell therapy optimization
This narrative review examines high-throughput screening technologies used to optimize adoptive T cell therapy (ACT).
High-throughput screening tools help overcome resistance in adoptive T cell therapy by identifying key targets and substances to boost cance…
Tucidinostat plus capecitabine shows 25.8% response in advanced HR-positive HER2-negative breast cancer
New Drug Combo Helps Breast Cancer After CDK4/6 Failure
This phase 2 trial evaluated tucidinostat plus metronomic capecitabine with endocrine therapy in 66 patients with HR-positive HER2-negative …
A new drug mix shrinks tumors in advanced breast cancer patients whose disease grew after standard treatments failed.
Talquetamab and teclistamab combination shows 79% response in relapsed multiple myeloma with extramedullary disease
Study looks at two antibody drugs for high-risk multiple myeloma
This phase 2 single-arm study evaluated a talquetamab and teclistamab combination in a high-risk population with relapsed/refractory multipl…
A new drug combo for high-risk multiple myeloma helped 79% of patients respond, but 31% faced serious infections and five treatment-related …
Meta-analysis reports high pooled complete response with ALA/MAL photodynamic therapy for superficial BCC
Light vs. Scalpel: New Skin Cancer Data
This PRISMA 2020 systematic review and meta-analysis of 55 studies (2123 patients, 2995 lesions) evaluated ALA-PDT and MAL-PDT for superfici…
Light therapy with cream may match surgery for treating common skin cancer while avoiding scars and functional damage to your face or neck.
Case report details endoscopic resection for sphenoid sinus myofibroma in a 60-year-old woman
Surgery for rare sphenoid sinus myofibroma in one patient showed no complications
This case report with narrative review describes endoscopic endonasal transsphenoidal resection in a 60-year-old female patient with sphenoi…
Endoscopic surgery successfully removed a rare skull base tumor in a 60-year-old woman, restoring her vision and relieving her pain without …
High FGR protein expression associated with worse relapse-free survival in de novo DLBCL patients treated with R-CHOP
New Protein Test Predicts Lymphoma Relapse Risk
This retrospective cohort study evaluated 91 patients with de novo diffuse large B-cell lymphoma treated with R-CHOP.
A new protein test identifies diffuse large B-cell lymphoma patients at high risk of relapse before treatment fails, giving doctors a crucia…
Salvage radiotherapy for limited metastatic relapse in small cell lung cancer after durvalumab
Two patients with limited-stage small cell lung cancer had durable disease control after salvage radiotherapy and immunotherapy
This case report describes two patients with limited-stage small cell lung cancer who developed limited metastatic relapse after chemoradiot…
Two limited-stage small cell lung cancer patients stayed stable for over four years after targeted radiation and continued immunotherapy.
Curative-intent local therapy linked to improved survival in isolated contralateral axillary breast metastasis
Local therapy linked to better survival in advanced breast cancer patients with specific metastases
This retrospective cohort study of 1110 patients across two tertiary centers compared outcomes in isolated contralateral axillary metastasis…
Patients with specific breast cancer spread to the opposite armpit survived longer when receiving surgery or radiation compared to systemic …
Multimodal CNN outperforms PSA alone for prostate cancer diagnosis in biopsy-confirmed patients
New MRI tool may improve prostate cancer diagnosis compared to PSA alone
This retrospective cohort study evaluated 305 patients with PSA levels 4–10 ng/mL who underwent multiparametric MRI and biopsy.
A new AI tool analyzing MRI scans correctly identified prostate cancer in 85.3% of cases and ruled it out in 90.9%, far outperforming PSA bl…
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Mouth Bacteria May Guide Breast Cancer Screening
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Tiny mouth bacteria might help doctors find breast cancer earlier by sending signals through your blood to warn of trouble.
FDA Approves Danziten (nilotinib) for Adult Patients with Newly Diagnosed or Resistant/Intolerant Ph+ CML
The FDA approved a new drug called Danziten for a type of blood cancer called CML
Danziten (nilotinib) is approved for adult patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML)…
The FDA approved Danziten to treat newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia or cases resistant to prior ima…
Meta-analysis of novel therapies for follicular lymphoma progression within 24 months shows high response rates
New treatments show high response rates for advanced follicular lymphoma patients
This systematic review and meta-analysis evaluated outcomes for patients with follicular lymphoma experiencing disease progression within 24…
New powerful medicines help 91% of advanced follicular lymphoma patients whose disease returned quickly after treatment.