Case report of semi-implantable IDDS for advanced cancer pain in three patients
Can a small pump stop severe cancer pain in just one day?
This case-based study describes three representative patients with advanced cancer pain treated with a semi-implantable intrathecal drug del…
A small pump delivered direct spinal medicine to three advanced cancer patients, dropping their worst pain from near maximum to zero within …
Meta-analysis shows KRASG12C inhibitors improve outcomes versus chemotherapy in KRAS-mutant NSCLC
New drugs stop lung cancer growth faster than chemo
This meta-analysis evaluated KRASG12C inhibitors versus conventional chemotherapy in 798 patients with KRASG12C-mutant non-small cell lung c…
New drugs targeting a specific lung cancer mutation stop tumor growth faster than standard chemotherapy while causing fewer severe side effe…
Case report of laparoscopic splenectomy with autotransplantation for PILA in a young male
Spleen Mass Mistaken for Benign: Rare Cancer Found in Young Adult
This case report describes a 21-year-old male with papillary intralymphatic angioendothelioma (PILA) treated with laparoscopic total splenec…
Doctors now know to look for a specific rare tumor in young people with spleen lumps, even if tests look normal.
Meta-analysis review synthesizes EDC exposure levels and metabolic markers in patients with PCOS versus controls
Chemicals in Your Body May Trigger PCOS
This meta-analysis review examines endocrine disrupting chemical (EDC) exposure in patients with polycystic ovary syndrome (PCOS) compared t…
Common environmental chemicals found in our daily lives might be silently increasing the risk of polycystic ovary syndrome.
Meta-analysis finds global BLV prevalence of 23.24% in cattle, with decline after 2018
Cattle Virus Hides in China While Global Numbers Drop
This meta-analysis of 44 studies synthesizes global and Chinese data on bovine leukemia virus (BLV) prevalence in cattle.
A hidden outbreak of a cancer-causing virus in Chinese cattle farms is growing fast even as the rest of the world sees fewer cases.
Meta-analysis links elevated DLEU1 expression to shorter survival in cancer patients
High DLEU1 levels in cancer tissue are linked to shorter life and worse tumor spread
This systematic review and meta-analysis of 938 cancer patients found that elevated DLEU1 expression was associated with shortened overall s…
High levels of a protein called DLEU1 in cancer tissue are linked to shorter life and worse tumor spread across 938 patients.
Neoadjuvant nivolumab alone or with ipilimumab in cisplatin-ineligible muscle-invasive bladder cancer
Hope for Bladder Cancer When Chemo Isn't an Option
This Phase II trial evaluated neoadjuvant nivolumab alone or with ipilimumab in 30 cisplatin-ineligible patients with muscle-invasive bladde…
Patients with advanced bladder cancer who can't take standard chemo may now qualify for surgery after a new immunotherapy treatment.
CyberKnife-SRT for brainstem glioma shows median overall survival of 20.9 months in retrospective cohort
CyberKnife May Help Rare Brain Tumor Patients Live Longer
This retrospective cohort study of 54 patients with brainstem glioma treated with CyberKnife-SRT found a median overall survival of 20.9 mon…
A new radiation technique called CyberKnife helps rare brainstem glioma patients live longer by sparing healthy tissue while treating the tu…
Review of ATRA and ATO induction therapy in acute promyelocytic leukemia with RNA sequencing insights
Why PCR Missed This Leukemia
This case report and literature review examines induction therapy using all-trans retinoic acid and arsenic trioxide in acute promyelocytic …
A standard blood test missed a dangerous leukemia because the disease had a unique genetic pattern that routine screening overlooked until a…
Case report of ATRA and VAH regimen in refractory EVI1-positive AML
New hope for tough AML cases
This case report with a brief literature review describes a 42-year-old patient with refractory EVI1-positive AML.
A patient with high-risk AML and the tough EVI1 marker achieved complete remission after failing standard treatments, offering new hope for …
Review supports Allo-HSCT for BCR-ABL(+) AML with TKI and chemotherapy
A New Hope for Rare Blood Cancer Patients
This case report and literature review addresses the treatment of BCR-ABL(+) acute myeloid leukemia.
Doctors helped a patient with rare BCR-ABL positive leukemia survive by combining drugs, chemotherapy, and a stem cell transplant.
Drug Response Profiling in pediatric ALL yields 68% objective responses and bridges to cellular therapies
Can a simple test find the right drug to save children with tough leukemia?
A prospective, multicenter Drug Response Profiling registry of 340 children with relapsed or refractory acute lymphoblastic leukemia in 17 E…
A simple test matching leukemia drugs to patient cells helped 68% of children respond to treatment and gave 28 of 42 patients a chance to su…