Frailty is associated with increased prevalence of depressive symptoms in adults with cancer
Frailty strongly linked to depression in cancer patients
A meta-analysis of cross-sectional studies examined the relationship between frailty and depression in adults with cancer.
Frail cancer patients are nearly six times more likely to struggle with depression, a major red flag for care teams and families.
Meta-analysis of bevacizumab therapy in recurrent glioblastoma multiforme shows associations with improved outcomes
Bevacizumab therapy linked to better survival and fewer bleeding risks in recurrent brain cancer
This meta-analysis evaluates bevacizumab (BEV) therapy, temozolomide (TMZ), and lomustine in patients with recurrent glioblastoma multiforme…
A large review of patients with recurrent brain cancer found bevacizumab therapy linked to better survival and fewer bleeding risks compared…
Darolutamide plus ADT delays pain progression in metastatic hormone-sensitive prostate cancer
New treatment delays pain in advanced prostate cancer
This randomised, double-blind, phase 3 trial in men with metastatic hormone-sensitive prostate cancer found that darolutamide plus androgen …
Men with advanced prostate cancer who took darolutamide stayed pain-free longer and felt better overall for months compared to those on stan…
Meta-analysis finds fluoroquinolone prophylaxis reduces febrile neutropenia in pediatric ALL
Fluoroquinolone antibiotics lower febrile neutropenia risk in children with acute lymphoblastic leukemia during treatment start
This systematic review and meta-analysis of 991 children with acute lymphoblastic leukemia found that fluoroquinolone prophylaxis reduced fe…
A review of children with acute lymphoblastic leukemia shows fluoroquinolone antibiotics reduce febrile neutropenia risk. This finding sugge…
Post-hoc analysis suggests regional hyperthermia plus chemotherapy may improve survival in extremity soft tissue sarcoma
Adding heat to chemo may improve survival for soft-tissue sarcoma patients
This post-hoc analysis of a randomized trial examined overall survival in patients with extremity soft tissue sarcoma receiving neoadjuvant …
A post-hoc analysis of a randomized trial suggests adding regional hyperthermia to chemotherapy improved survival for patients with extremit…
Meta-analysis of pucotenlimab shows improved outcomes across multiple solid tumors
New analysis shows pucotenlimab improves outcomes for several solid tumor types
This meta-analysis evaluated pucotenlimab (HX008) in patients with gastric, gastroesophageal junction, triple-negative breast cancer, melano…
A new analysis of pucotenlimab shows significantly improved outcomes versus control for patients with gastric cancer, triple-negative breast…
PSA levels at 6, 12, and 24 weeks post-randomization correlate with 96-month survival in prostate cancer
Low PSA at 24 weeks predicts longer survival in prostate cancer
This post-hoc analysis of five phase 3 trials in 7129 patients with prostate cancer found that 96-month overall survival varied by metastati…
Men with prostate cancer who hit a PSA level of 0.2 ng/mL or less within 24 weeks of starting treatment are far more likely to survive at le…
Adding adrenaline to bupivacaine for lipoma plane block reduces blood loss and pain
Adrenaline in local blocks reduces pain and bleeding during lipoma surgery
This prospective randomized trial in 40 adults undergoing lipoma excision found that adding adrenaline (1:200,000) to bupivacaine for ultras…
Adding adrenaline to a local anesthetic block lessened pain and bleeding for patients having lipoma removal, based on a trial of 40 adults.
Pilot study explores ketogenic diet effects on symptoms in adults with generalized myasthenia gravis
Ketogenic diet may improve daily function in myasthenia gravis
This randomized, controlled, open-label pilot study examined whether a ketogenic diet improves functional status and quality of life in adul…
A small pilot trial hints that a keto diet could ease daily struggles for people with myasthenia gravis, but larger studies are needed.
Mecapegfilgrastim reduces grade 3+ neutropenia in treatment-naive diffuse large B-cell lymphoma patients versus no prophylaxis
New Drug Cuts Severe Infection Risk In Lymphoma Care
This randomized controlled trial evaluated mecapegfilgrastim in 42 treatment-naive patients with diffuse large B-cell lymphoma.
A new long-acting injection lowers the risk of dangerous low white blood cell counts in lymphoma patients starting their first round of chem…
Digital collaboration with patient representatives reduces travel costs and effort in psycho-oncology research
Digital collaboration reduces costs and barriers for cancer patients
This qualitative study involved 5 patient representatives from the Reduct trial.
A small qualitative study suggests digital tools may lower travel costs and improve flexibility for cancer patients, though technical and co…
Lyophilized pegaspargase shows similar activity to liquid form in pediatric ALL
Lyophilized pegaspargase shows similar activity and safety to liquid form for pediatric leukemia patients
This phase 2 study in 89 pediatric ALL patients in Russia found that lyophilized pegaspargase had similar maximum plasma asparaginase activi…
A new form of pegaspargase works just like the liquid version for treating acute lymphoblastic leukemia in children in Russia.