Meta-analysis finds global BLV prevalence of 23.24% in cattle, with decline after 2018
Cattle Virus Hides in China While Global Numbers Drop
This meta-analysis of 44 studies synthesizes global and Chinese data on bovine leukemia virus (BLV) prevalence in cattle.
A hidden outbreak of a cancer-causing virus in Chinese cattle farms is growing fast even as the rest of the world sees fewer cases.
Meta-analysis links elevated DLEU1 expression to shorter survival in cancer patients
High DLEU1 levels in cancer tissue are linked to shorter life and worse tumor spread
This systematic review and meta-analysis of 938 cancer patients found that elevated DLEU1 expression was associated with shortened overall s…
High levels of a protein called DLEU1 in cancer tissue are linked to shorter life and worse tumor spread across 938 patients.
Neoadjuvant nivolumab alone or with ipilimumab in cisplatin-ineligible muscle-invasive bladder cancer
Hope for Bladder Cancer When Chemo Isn't an Option
This Phase II trial evaluated neoadjuvant nivolumab alone or with ipilimumab in 30 cisplatin-ineligible patients with muscle-invasive bladde…
Patients with advanced bladder cancer who can't take standard chemo may now qualify for surgery after a new immunotherapy treatment.
CyberKnife-SRT for brainstem glioma shows median overall survival of 20.9 months in retrospective cohort
CyberKnife May Help Rare Brain Tumor Patients Live Longer
This retrospective cohort study of 54 patients with brainstem glioma treated with CyberKnife-SRT found a median overall survival of 20.9 mon…
A new radiation technique called CyberKnife helps rare brainstem glioma patients live longer by sparing healthy tissue while treating the tu…
Review of ATRA and ATO induction therapy in acute promyelocytic leukemia with RNA sequencing insights
Why PCR Missed This Leukemia
This case report and literature review examines induction therapy using all-trans retinoic acid and arsenic trioxide in acute promyelocytic …
A standard blood test missed a dangerous leukemia because the disease had a unique genetic pattern that routine screening overlooked until a…
Case report of ATRA and VAH regimen in refractory EVI1-positive AML
New hope for tough AML cases
This case report with a brief literature review describes a 42-year-old patient with refractory EVI1-positive AML.
A patient with high-risk AML and the tough EVI1 marker achieved complete remission after failing standard treatments, offering new hope for …
Review supports Allo-HSCT for BCR-ABL(+) AML with TKI and chemotherapy
A New Hope for Rare Blood Cancer Patients
This case report and literature review addresses the treatment of BCR-ABL(+) acute myeloid leukemia.
Doctors helped a patient with rare BCR-ABL positive leukemia survive by combining drugs, chemotherapy, and a stem cell transplant.
Drug Response Profiling in pediatric ALL yields 68% objective responses and bridges to cellular therapies
Can a simple test find the right drug to save children with tough leukemia?
A prospective, multicenter Drug Response Profiling registry of 340 children with relapsed or refractory acute lymphoblastic leukemia in 17 E…
A simple test matching leukemia drugs to patient cells helped 68% of children respond to treatment and gave 28 of 42 patients a chance to su…
Comprehensive geriatric assessment modifies treatment plans and associates with survival in older adults with gastrointestinal malignancies
Does a pre-surgery check-up actually change treatment plans and help older adults with cancer live longer?
This retrospective cohort study evaluated 273 adults aged ≥65 years referred for preoperative comprehensive geriatric assessment (CGA) at a …
A pre-surgery health check changed treatment plans for 21% of older cancer patients and was linked to better survival.
CT radiomics and transcriptomics predict chemotherapy response in advanced laryngeal cancer
New Scan Predicts Chemo Success Before Treatment Starts
A retrospective cohort study of 161 advanced laryngeal cancer patients found that a Random Forest model combining CT radiomics, transcriptom…
A new scan using CT images can predict if chemotherapy will work for advanced laryngeal cancer before treatment begins, helping doctors avoi…
CLEC14A methylation marker detects HSIL and cervical cancer with 100% sensitivity and 95.3% specificity in a cohort of 431 participants
Can a simple blood test spot dangerous cervical cell changes before they become cancer?
This cohort study of 431 participants evaluated the CLEC14A cg05057720 methylation marker for detecting high-grade squamous intraepithelial …
A new blood test marker detects every case of dangerous cervical cell changes while correctly identifying normal tissue in over 95% of cases…
Classification framework shows 79% to 98% performance for oral squamous cell carcinoma on histopathological images
AI Learns to Ignore Stains to Spot Mouth Cancer
A computer-aided classification study evaluated a framework combining staining-bias suppression and structured multiple-instance aggregation…
New AI technology learns to ignore stain colors, helping doctors spot mouth cancer more accurately even when lab dyes vary.