Narrative review discusses adapter-based CAR T cells for solid tumors and hematological malignancies.
Adapter-based CAR T cells face hurdles in treating solid tumors and blood cancers.
This narrative review examines the potential of adapter-based CAR T cells across multiple cancer types, including solid tumors and hematolog…
A review highlights that making these cells is hard work and they struggle against solid tumors, limiting their current use.
Ultrasound radiomics features aid preoperative differentiation of granulomatous lobular mastitis and breast cancer in a retrospective cohort.
Ultrasound Can Spot This Breast Condition Before Surgery
This retrospective cohort study evaluated ultrasound radiomics features in 237 patients with granulomatous lobular mastitis or breast cancer…
Many women face a scary moment when a lump appears in their breast.
Tisagenlecleucel in Korean patients with relapsed or refractory diffuse large B-cell lymphoma
New Lymphoma Therapy Helps Patients Live Longer
This retrospective cohort study of 79 Korean patients with relapsed or refractory diffuse large B-cell lymphoma evaluated tisagenlecleucel. …
A new study shows a specific immune therapy can shrink tumors and extend life for lymphoma patients who have run out of options.
CIPHER model predicts immune checkpoint inhibitor pneumonitis risk in non-small cell lung cancer patients
Lung Scans Can Now Predict Dangerous Side Effect Before Treatment
This cohort study evaluated a CIPHER model versus classical radiomic models for predicting immune checkpoint inhibitor-induced pneumonitis i…
This tool could help doctors protect patients before a serious side effect strikes.
Meta-analysis identifies new genetic loci linked to acute myeloid leukemia risk in 4710 cases.
New Genetic Map Reveals Hidden Leukemia Risk Factors
This meta-analysis evaluated common genetic variants at 1q23.3, 2p23.3, 2q33.3, and 2p21 in 4710 AML cases and 12,938 controls. The authors …
New research pinpoints specific DNA changes that raise the odds of developing acute myeloid leukemia.
Systematic review of cold vs warm sodium hypochlorite irrigation for postoperative pain in root canal therapy
Cold Rinse Cuts Tooth Pain After Root Canals
This narrative systematic review evaluates postoperative pain in patients undergoing root canal therapy using cold versus warm or room tempe…
A simple change in root canal care—using a cold rinse instead of warm—could reduce pain in the first hours after treatment, offering relief …
Machine learning quantification of Gleason Pattern 4 showed higher discrimination for adverse pathology than grade group in prostate cancer.
AI Measures Prostate Cancer Risk More Accurately Than Standard Methods
This proof-of-principle cohort study evaluated 726 patients with grade group 2-4 prostate cancer on systematic biopsy who underwent radical …
A new AI tool can spot dangerous prostate cancer patterns better than current grading, offering men a clearer picture of what to expect afte…
Plasma lipid panel and machine learning for non-invasive early breast cancer detection
Researchers find blood test spots early breast cancer
This observational cohort study used a 15-lipid panel and machine learning to detect early-stage breast cancer in women across international…
A new blood test using lipids and machine learning shows promise for detecting early-stage breast cancer, with strong results in European an…
Narrative review explores exosomal non-coding RNAs in osteoarthritis pathogenesis and therapy
Tiny Messengers in Your Joints Could Change Osteoarthritis Care
This narrative review summarizes the role of exosomal non-coding RNAs in osteoarthritis. It discusses their involvement in disease pathogene…
Scientists are learning how to use your body’s own tiny messengers to calm inflamed joints and potentially slow osteoarthritis.
Narrative review discusses NTS1-targeted molecular probes for malignancies with noted translation challenges.
New Cancer Scan Targets Tumors Hidden from View
This narrative review examines the potential of NTS1-targeted molecular probes for treating malignancies. The authors provide a useful refer…
Researchers are building a smarter tool to find and treat cancer cells more accurately.
Narrative review on AI and digital pathology for breast and gynecologic cancers
New AI Tools Read Tumor DNA Like a Book
This narrative review synthesizes evidence on integrating digital and molecular pathology with AI and machine learning for breast and gyneco…
Combining microscope images with genetic data gives doctors a much clearer picture of how to treat cancer patients.
Color customization of removable orthodontic appliances in children: perceptions and adherence
Bright braces boost mood, but do they actually help kids wear them longer?
This retrospective cross-sectional study in 316 children aged 8–16 years assessed perceptions of color-customized removable orthodontic appl…
While bright colors make kids feel happier about their braces, the study found they did not actually help children wear their appliances mor…