Phase II RCT finds no benefit for adding capecitabine to 177Lu-Dotatate in advanced NETs
Adding a Drug Actually Hurted These Patients
A Phase II randomized controlled trial in 111 patients with advanced somatostatin receptor-positive GEP or bronchopulmonary NETs compared…
Adding a common chemotherapy drug to cancer treatment actually made tumors grow faster and reduced survival time for these patients.
Pembrolizumab plus chemotherapy versus placebo plus chemotherapy in Chinese adults with advanced biliary tract carcinoma
Could adding pembrolizumab help Chinese adults live longer with advanced biliary tract carcinoma?
This phase 3 randomized controlled trial enrolled 158 Chinese adults with advanced or unresectable biliary tract carcinoma.
A completed study in China compared adding pembrolizumab to chemotherapy for advanced bile duct cancer, tracking how long 158 adults survive…
Subcutaneous PEG-rhG-CSF reduced grade ≥3 neutropenia and CIN in GI cancer patients receiving oral chemotherapy
New Shot Cuts Severe Low White Blood Cell Risk
This prospective, single-center, open-label, exploratory, non-randomized controlled study evaluated subcutaneous PEG-rhG-CSF in 43 gastroint…
A simple shot given before chemotherapy could keep your body's infection-fighting cells strong when taking oral cancer pills.
Case report of semi-implantable IDDS for advanced cancer pain in three patients
Can a small pump stop severe cancer pain in just one day?
This case-based study describes three representative patients with advanced cancer pain treated with a semi-implantable intrathecal drug del…
A small pump delivered direct spinal medicine to three advanced cancer patients, dropping their worst pain from near maximum to zero within …
Meta-analysis shows KRASG12C inhibitors improve outcomes versus chemotherapy in KRAS-mutant NSCLC
New drugs stop lung cancer growth faster than chemo
This meta-analysis evaluated KRASG12C inhibitors versus conventional chemotherapy in 798 patients with KRASG12C-mutant non-small cell lung c…
New drugs targeting a specific lung cancer mutation stop tumor growth faster than standard chemotherapy while causing fewer severe side effe…
Meta-analysis review synthesizes EDC exposure levels and metabolic markers in patients with PCOS versus controls
Chemicals in Your Body May Trigger PCOS
This meta-analysis review examines endocrine disrupting chemical (EDC) exposure in patients with polycystic ovary syndrome (PCOS) compared t…
Common environmental chemicals found in our daily lives might be silently increasing the risk of polycystic ovary syndrome.
Meta-analysis finds global BLV prevalence of 23.24% in cattle, with decline after 2018
Cattle Virus Hides in China While Global Numbers Drop
This meta-analysis of 44 studies synthesizes global and Chinese data on bovine leukemia virus (BLV) prevalence in cattle.
A hidden outbreak of a cancer-causing virus in Chinese cattle farms is growing fast even as the rest of the world sees fewer cases.
Case report of laparoscopic splenectomy with autotransplantation for PILA in a young male
Spleen Mass Mistaken for Benign: Rare Cancer Found in Young Adult
This case report describes a 21-year-old male with papillary intralymphatic angioendothelioma (PILA) treated with laparoscopic total splenec…
Doctors now know to look for a specific rare tumor in young people with spleen lumps, even if tests look normal.
Meta-analysis links elevated DLEU1 expression to shorter survival in cancer patients
High DLEU1 levels in cancer tissue are linked to shorter life and worse tumor spread
This systematic review and meta-analysis of 938 cancer patients found that elevated DLEU1 expression was associated with shortened overall s…
High levels of a protein called DLEU1 in cancer tissue are linked to shorter life and worse tumor spread across 938 patients.
Neoadjuvant nivolumab alone or with ipilimumab in cisplatin-ineligible muscle-invasive bladder cancer
Hope for Bladder Cancer When Chemo Isn't an Option
This Phase II trial evaluated neoadjuvant nivolumab alone or with ipilimumab in 30 cisplatin-ineligible patients with muscle-invasive bladde…
Patients with advanced bladder cancer who can't take standard chemo may now qualify for surgery after a new immunotherapy treatment.
CyberKnife-SRT for brainstem glioma shows median overall survival of 20.9 months in retrospective cohort
CyberKnife May Help Rare Brain Tumor Patients Live Longer
This retrospective cohort study of 54 patients with brainstem glioma treated with CyberKnife-SRT found a median overall survival of 20.9 mon…
A new radiation technique called CyberKnife helps rare brainstem glioma patients live longer by sparing healthy tissue while treating the tu…
Review of ATRA and ATO induction therapy in acute promyelocytic leukemia with RNA sequencing insights
Why PCR Missed This Leukemia
This case report and literature review examines induction therapy using all-trans retinoic acid and arsenic trioxide in acute promyelocytic …
A standard blood test missed a dangerous leukemia because the disease had a unique genetic pattern that routine screening overlooked until a…