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Oncology

1102 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Survey wording affects nicotine-cancer belief prevalence from 10% to 81% in US adults
Oncology RCT
Survey wording affects nicotine-cancer belief prevalence from 10% to 81% in US adults How you ask the question changes what people believe about nicotine and cancer
A randomized survey experiment of 2,526 US adults found 36% correctly believed nicotine does not cause cancer, but prevalence varied from 10…
How you ask the question changes what people believe about nicotine and cancer, with correct answers ranging from 10% to 81% depending on su…
Left atrial strain, resected segments predict post-lung resection exercise decline in 38-patient study
Oncology
Left atrial strain, resected segments predict post-lung resection exercise decline in 38-patient study Why does lung surgery leave some people struggling to breathe? The answer might be in how the heart and lungs work together
In 38 patients undergoing lung resection, postoperative peak VO2 decreased from 19.4 to 17.3 mL/min/kg (P<0.001).
Lung surgery often leaves patients struggling to breathe because removing more lung tissue stresses blood vessels and weakens the heart's ab…
Nivolumab+ipilimumab shows 5-year OS benefit (14% vs 6%) vs chemo in unresectable pleural mesothelioma
Oncology RCT
Nivolumab+ipilimumab shows 5-year OS benefit (14% vs 6%) vs chemo in unresectable pleural mesothelioma Can immunotherapy help people with advanced mesothelioma live longer? Five-year results show it can
In the 5-year follow-up of CheckMate 743, nivolumab plus ipilimumab demonstrated continued overall survival benefit versus chemotherapy in u…
Five years after starting treatment, 14% of advanced mesothelioma patients survived on immunotherapy versus 6% on chemotherapy, proving last…
VATS lobectomy improves overall survival vs open surgery in early-stage NSCLC
Oncology Meta-analysis
VATS lobectomy improves overall survival vs open surgery in early-stage NSCLC Does a less invasive lung cancer surgery help people live longer? New analysis says yes
An individual patient data meta-analysis of 3 RCTs (n=1185) found VATS lobectomy for early-stage NSCLC was associated with a 21% mortality r…
A new analysis of nearly 1,200 patients shows less invasive lung surgery lowers the risk of death by 21% compared to traditional open surger…
Low sADC Predicts Poor Outcomes in Cervical Cancer with PD-1 Inhibitors
Oncology Cohort
Low sADC Predicts Poor Outcomes in Cervical Cancer with PD-1 Inhibitors Can imaging predict how well cervical cancer patients respond to treatment?
In a study of 167 cervical cancer patients, lower substantial ADC (sADC) correlated with worse PFS (HR=1.81, P=0.005) and OS (HR=2.40, P=0.0…
Low water movement in cervical cancer tumors on scans predicts worse survival when patients take immunotherapy, helping doctors choose bette…
Meta-analysis: Zinc supplements show time-dependent efficacy in preventing oral mucositis after chemoradiotherapy
Oncology Meta-analysis
Meta-analysis: Zinc supplements show time-dependent efficacy in preventing oral mucositis after chemoradiotherapy Can a simple mineral help cancer patients avoid painful mouth sores from treatment? New analysis says yes, with timing being key
A meta-analysis of 16 RCTs (n≈1076) found zinc supplementation significantly delayed OM onset (MD=1.37, 95% CI: 0.78 to 1.95, P<0.001) and r…
Zinc supplements delay painful mouth sores in cancer patients and reduce risk at 2 weeks and 7-9 weeks, with timing and dosage being key to …
Higher TFF1 Expression Linked to Lower Bilateral Retinoblastoma Risk
Oncology Meta-analysis
Higher TFF1 Expression Linked to Lower Bilateral Retinoblastoma Risk Could a simple test help identify retinoblastoma risk in children?
In a meta-analysis of 521 retinoblastoma patients, higher TFF1 expression was linked to reduced bilateral involvement (RR=0.57, p=0.0041) an…
A new test for a protein called TFF1 could help doctors spot retinoblastoma risk in children and predict if the cancer will affect both eyes…
Guided Breathing VR Reduces Opioid Use Post-PTBD in Cancer Patients by 64%
Oncology RCT
Guided Breathing VR Reduces Opioid Use Post-PTBD in Cancer Patients by 64% Can Virtual Reality and Breathing Techniques Reduce Cancer Pain?
In a randomized trial, guided breathing VR (VRBG) significantly reduced opioid use post-PTBD compared to conventional VR (VROG), with a mean…
Cancer patients using virtual reality with guided breathing took significantly less pain medication after a painful procedure than those usi…
Atezolizumab with mFOLFOX6 Boosts 3-Year DFS by 10.1% in Stage III dMMR Colon Cancer
Oncology RCT
Atezolizumab with mFOLFOX6 Boosts 3-Year DFS by 10.1% in Stage III dMMR Colon Cancer Could a New Treatment Boost Survival for Stage III Colon Cancer Patients?
In a phase 3 trial, atezolizumab plus mFOLFOX6 improved 3-year disease-free survival to 86.3% vs. 76.2% with mFOLFOX6 alone (HR 0.50; 95% CI…
Adding atezolizumab to standard chemotherapy boosted 3-year disease-free survival to 86% in stage III colon cancer patients, up from 76% wit…
CSF ctDNA Status Predicts Survival in Leptomeningeal Metastases: Meta-Analysis
Oncology Meta-analysis
CSF ctDNA Status Predicts Survival in Leptomeningeal Metastases: Meta-Analysis Can a Simple Test in Spinal Fluid Predict Survival for Cancer Patients?
In a meta-analysis of 14 studies (n=963), adverse baseline CSF ctDNA status was linked to worse OS (HR 2.40, 95% CI 1.73-3.33) and PFS (HR 2…
A simple spinal fluid test can predict how long someone with advanced cancer might live by spotting DNA markers linked to shorter survival t…