Robotic-assisted treadmill training improves walking measures in children with spastic diplegic cerebral palsy
Robotic treadmill training may help walking in children with cerebral palsy
A randomized controlled trial in 40 children with spastic diplegia found that adding robotic-assisted treadmill gait training to regular phy…
Adding robotic treadmill training to regular therapy helped children with spastic diplegia walk faster and take longer steps.
Phase 3 RCT: Ataluren shows favorable trend for slowing functional decline in nonsense mutation DMD
Can a drug help boys with Duchenne muscular dystrophy walk longer?
A phase 3 RCT of 359 people with nonsense mutation Duchenne muscular dystrophy found that 72 weeks of ataluren treatment was associated with…
Boys with a specific genetic form of Duchenne muscular dystrophy who took ataluren saw their walking ability decline less over 72 weeks than…
Cognitive training programs ARAM and PETRA show improvements in ADHD symptoms and executive functions in preschoolers
Two cognitive training programs show promise for preschoolers with ADHD in small study
A randomized controlled trial in 47 preschool children with ADHD found that both ARAM and PETRA cognitive training programs improved inhibit…
Two cognitive training programs improved attention and behavior in preschoolers with ADHD, with one showing slightly larger daily life benef…
Methylphenidate plus iron shows earlier response in children with severe ADHD and iron deficiency
Iron supplements with ADHD medication may help children with both conditions
A small RCT of 50 children with severe ADHD and iron deficiency in Bangladesh compared methylphenidate plus iron to methylphenidate alone ov…
Adding iron supplements to ADHD medication helped children with both conditions improve symptoms faster than medication alone.
Benzodiazepines, Dexmedetomidine, and Physical Restraints Associated with Next-Day Delirium in Critically Ill Children
Study finds link between certain medications, restraints, and delirium in critically ill children
A secondary analysis of a pilot RCT dataset in 1,006 critically ill children across seven PICUs found previous-day benzodiazepine and dexmed…
Higher doses of sedatives like midazolam and any use of physical restraints are linked to increased confusion in critically ill children the…
Video feedback intervention shows significant effects on maternal sensitivity in cerebral palsy dyads
Video feedback parenting program shows promise for mothers of children with cerebral palsy
A small RCT of 40 mother-child dyads where the child has cerebral palsy found that the VIPP-CP intervention had significant effects on speci…
A video feedback program helped mothers of children with cerebral palsy become more supportive, sensitive, and encouraging during play.
OPEP device added to chest physiotherapy improves adherence but not clinical outcomes in children with bronchiectasis
Adding a breathing device to chest physiotherapy improved adherence but not clinical outcomes in children with bronchiectasis
In a randomized trial of 42 children with bronchiectasis, an 8-week multicomponent chest physiotherapy program improved exercise capacity an…
Adding a breathing device to chest physiotherapy helped children stick to their routine but offered no extra lung benefits for those with br…
Cervical pessary versus progesterone for preterm birth prevention in twin pregnancy with short cervix
For twin pregnancies with a short cervix, does a cervical pessary help prevent early birth?
A small, single-center RCT in 34 individuals with twin pregnancy and cervical length ≤38 mm compared cervical pessary to vaginal progesteron…
For twin pregnancies with a short cervix, a new study found that daily vaginal progesterone led to fewer complications and less early birth …
Cross-sectional study finds physical fitness components associated with cognitive domains in preschoolers
Preschoolers with better fitness scores show better thinking skills in study
A cross-sectional analysis of baseline RCT data in 522 Spanish preschoolers aged 3-5 years found all health-related physical fitness compone…
Preschoolers with better fitness scores generally show better thinking skills in areas like vocabulary, memory, and problem-solving.
Unconditional cash transfers increase parental investment more in lower-opportunity neighborhoods
How does a neighborhood shape what parents buy and do for their kids?
A randomized trial of 1000 low-income mothers and newborns found that larger unconditional cash transfers ($333 vs $20 monthly) led to great…
Parents in low-opportunity neighborhoods who received extra cash invested more in their children's development than those in wealthier areas…
Meta-analysis finds spanking no more effective than other strategies for child compliance
Research review finds spanking no more effective than other discipline strategies
A meta-analysis of four controlled trials found no significant difference in child compliance between disciplinary spanking and other…
A review of old spanking trials found they lack validity and show no better results than other discipline methods for getting children to co…
School-based resilience interventions reduce adolescent tobacco, alcohol, and illicit substance use
School resilience programs linked to lower substance use in students
A meta-analysis of school-based studies in students aged 6-18 years found resilience interventions were associated with reduced substance us…
School resilience programs that teach coping skills are linked to lower tobacco, alcohol, and drug use among students aged 6 to 18.