AI visual psychophysiological analysis shows high sensitivity for depression screening in 98 outpatients
AI tool shows promise for screening depression and anxiety in small outpatient study
A prospective diagnostic study of 98 outpatients found an AI-based visual psychophysiological analysis platform had 95.9% sensitivity for de…
An AI tool analyzing head vibrations detected depression risk in 96% of patients, outperforming standard questionnaires when used alone or t…
P50 sensory gating deficits linked to depressive symptoms in adolescents with non-suicidal self-injury
Brain signal differences found in teens who self-harm and have depression
An observational study of 86 adolescents with NSSI and 50 healthy controls found P50 sensory gating deficits (higher S2/S1 ratio and S2 ampl…
Teens who self-harm and feel depressed show weaker brain signals that make it harder to filter out repeated sounds.
Child mental health symptoms declined as COVID-19 restrictions eased in Ontario longitudinal study
Children's mental health symptoms improved as COVID-19 restrictions loosened in Ontario study
A population-based longitudinal study of 1,261 children and youth in Ontario found mental health symptoms were elevated during lockdowns but…
When Ontario COVID restrictions loosened, children's behavioral symptoms like oppositional behavior and inattention improved significantly m…
Meta-analysis links auditory hallucinations in schizophrenia to specific brain activity patterns and neurotransmitter systems
Brain activity patterns linked to hearing voices in schizophrenia, research review finds
A systematic review and meta-analysis of neuroimaging studies in schizophrenia patients with auditory verbal hallucinations found AVH associ…
Hearing voices in schizophrenia is linked to increased brain activity in hearing and language areas alongside decreased activity in sensorim…
EMR-integrated CDSS improves diagnostic concordance for mood disorders among psychiatrists
Study finds computer tool helps psychiatrists agree on mood disorder diagnoses
In an RCT of 72 psychiatrists, an EMR-integrated clinical decision support system significantly improved diagnostic concordance, particularl…
A computer tool helps psychiatrists agree on diagnoses for depression and bipolar disorder, but offers no boost for schizophrenia or experie…
Protocol outlines target trial emulation for bipolar disorder treatments in patients with opioid use disorder
Study protocol compares bipolar disorder medications for people with opioid use disorder
This protocol describes a planned target trial emulation study using population-level administrative data from British Columbia and Ontario,…
People with bipolar disorder and opioid use disorder face higher risks, but a new plan will compare how well different medications work for …
Vitamin D deficiency associated with depression in adolescents and young adults, stronger in females
Vitamin D deficiency linked to depression in adolescents and young adults, especially females
A systematic review and meta-analysis of 27,956 adolescents and young adults found vitamin D deficiency (<50 nmol/L) was associated with dep…
Young people with low vitamin D levels are twice as likely to have depression, a link that is especially strong in females.
Protocol published for trial testing tDCS plus cognitive training in schizophrenia
Researchers plan trial to test brain stimulation plus cognitive training for schizophrenia
A study protocol describes a future randomized controlled trial of 120 adults with stable schizophrenia. The trial will compare active tDCS …
A new trial plans to test if gentle brain stimulation combined with computer training improves thinking and memory for people with schizophr…
Gray matter volume deviations in schizophrenia linked to symptom severity and cognitive function
Can brain volume patterns help us understand schizophrenia symptoms?
An observational cohort study of 379 schizophrenia spectrum disorder patients and 149 healthy controls found that more negative gray matter …
A scattered pattern of less brain tissue linked to focusing on important details predicts how severe schizophrenia symptoms are.
Antipsychotic exposure shows time-dependent associations with vocational recovery in schizophrenia cohort
Do antipsychotics help people with schizophrenia get back to work or school?
A Danish register-based cohort study of 65,630 individuals with incident schizophrenia spectrum disorders found antipsychotic exposure was a…
Antipsychotic medication use initially lowers work or school chances for schizophrenia patients but eventually shows a small positive link a…
Movement patterns during threat task associated with symptom profiles in young children
How do anxious children move differently when they feel threatened?
An observational laboratory study of 91 children aged 4-8 years found that internalizing symptoms were associated with smaller turning angle…
Wearable sensors show anxious children turn less when threatened, but those with both anxiety and aggression turn more, signaling different …
Caregivers of dementia patients report insufficient support for nighttime agitation
What happens when dementia keeps someone awake at night? Caregivers feel alone.
A qualitative study of 15 informal caregivers of people with dementia found they feel insufficiently supported when managing nighttime agita…
When dementia keeps someone awake at night, caregivers feel alone and unsupported, relying on self-made coping methods because current help …