Manual acupuncture reduces anxiety symptoms versus sham and usual care in meta-analysis of 20 RCTs
Manual acupuncture shows promise for reducing anxiety symptoms in research review
A meta-analysis of 20 RCTs (1,462 patients with anxiety) found manual acupuncture significantly reduced anxiety versus sham acupuncture (SMD…
Manual acupuncture reduced anxiety symptoms better than fake needles or waiting lists immediately after treatment, though benefits against u…
Meta-analysis finds mGluR modulators show no significant efficacy for schizophrenia symptoms
Study finds experimental schizophrenia drugs not more effective than current treatments
A meta-analysis of 10 RCTs involving 3715 participants with schizophrenia found that mGluR agonists and positive allosteric modulators (POMA…
New experimental drugs for schizophrenia did not improve symptoms better than current standard treatments and caused more side effects leadi…
Nutrition interventions may improve depression, anxiety, and diabetes distress in adults with diabetes
Can changing what you eat help ease the mental burden of diabetes?
A meta-analysis of 30 publications in adults with diabetes found nutrition interventions improved depression and anxiety scores and lowered…
Adjusting your diet to balance proteins, fats, and carbs can lower the specific distress of managing diabetes, though supplements helped eas…
Meta-analysis finds virtual reality exposure therapy reduces anxiety and PTSD symptoms
Can virtual reality help people face their fears? A new analysis suggests it might
A meta-analysis of 26 RCTs involving 1,649 patients with anxiety-related disorders and PTSD found virtual reality exposure therapy significa…
Virtual reality exposure therapy significantly reduces phobia, anxiety, and PTSD symptoms while helping people face their deepest fears.
Supportive nursing interventions reduce stress for mothers of NICU infants in meta-analysis
Can simple nursing support ease the crushing stress for mothers in the NICU?
A systematic review and meta-analysis of 22 studies involving 1,877 mothers with infants in NICUs found that supportive nursing intervention…
Structured emotional support from NICU nurses significantly lowers stress for mothers of newborns in intensive care, though the benefit size…
Meta-analysis identifies distinct and shared amygdala connectivity patterns in major depression and bipolar disorder
Do depression and bipolar disorder show different brain wiring patterns?
A voxel-wise meta-analysis of neuroimaging studies compared amygdala functional connectivity in patients with major depressive disorder and …
Brain scans show depression and bipolar disorder have different wiring in memory areas but share abnormalities in emotion control regions.
Systematic review links trauma exposure to epigenetic changes in stress, immune, and neurodevelopmental pathways
Can trauma change our biology in ways that affect our children?
A systematic review examined epigenetic changes associated with acute, chronic, and complex traumatic exposures.
Severe stress can leave molecular marks on the body that affect how we handle stress, our immune system, and even increase vulnerability for…
Scoping review maps 31 U.S. interventions for opioid use disorder during pregnancy by socioecological level
What helps pregnant women with opioid addiction? A new review maps the options
A scoping review of 31 U.S. intervention studies for pregnant individuals with opioid use disorder found 55% focused on individual-level app…
A review of U.S. research found 31 interventions for pregnant women with opioid addiction, with over half focusing on individual care like m…
Meta-analysis finds mixed MRI patterns in subgenual cingulate cortex in medication-free MDD patients
What does depression look like in the brain? The picture is complicated
A systematic review and meta-analysis of 42 publications compared medication-free MDD patients to healthy controls using MRI.
Depression scans show mixed results for brain size and activity, but consistently reveal weaker connections in an emotional hub when the bra…
Psychotropic medications frequently cause metabolic adverse effects via gut-brain axis
Why do psychiatric medications often cause weight gain and diabetes?
A narrative review synthesizes emerging evidence on psychotropic-induced metabolic disturbances.
Psychiatric drugs often cause weight gain and diabetes by disrupting the gut-brain-metabolic axis, a link new science is starting to map.
Transcriptomic meta-analysis in bipolar disorder identifies mitochondrial, synaptic, and inflammatory pathway genes
Gene analysis in bipolar disorder finds links to energy, inflammation, and signaling pathways
A meta-analysis of 917 brain and 638 blood samples from BD patients and controls found enrichment of genes involved in mitochondrial bioener…
Gene analysis reveals that bipolar disorder disrupts brain energy production, stress response, and inflammation pathways, pointing to specif…
Fatal serotonin syndrome in Parkinson's patient on rasagiline after sequential SSRI administration
Case report describes fatal serotonin syndrome in older Parkinson's patient on multiple medications
A case report describes a 72-year-old Parkinson's patient on rasagiline who developed fatal serotonin syndrome after sequential sertraline a…
A 72-year-old Parkinson's patient died after taking two antidepressants with a genetic makeup that slowed drug processing, causing fatal ser…