Co-administration of CD19 and CD22 CAR-T therapy in pediatric relapsed/refractory Philadelphia chromosome-positive acute lymphoblastic leukemia
Years Later, These Kids With Tough Leukemia Are Still in Remission
This retrospective subanalysis evaluated long-term outcomes in pediatric patients with relapsed/refractory Philadelphia chromosome-positive …
Pairing two reprogrammed immune cell therapies gave most kids with an aggressive form of leukemia long-term remission — without a single tre…
Spontaneous pneumomediastinum in anti-MDA5 dermatomyositis-ILD carries high mortality in small case series
A CT Score That May Flag the Sickest Lung Patients First
A retrospective case series of 9 patients with anti-MDA5 antibody-positive dermatomyositis-associated interstitial lung disease (ILD) compli…
In a small but urgent study, a CT-based score may help doctors spot the patients who need the most aggressive treatment — before it's too la…
CFP10 immunohistochemistry shows high sensitivity for renal tuberculosis in surgical specimens
New Test Finds Hidden TB in Kidney Tissue
A retrospective cohort study of 86 patients with surgically resected renal tissue found CFP10 immunohistochemical staining had 91.8% sensiti…
A new kidney test spots hidden tuberculosis by finding a specific protein that standard methods often miss, helping doctors catch the infect…
RDW trajectories during sepsis hospitalization predict 30- and 90-day mortality in retrospective study
Why a simple blood test predicts who gets sicker
A retrospective cohort study of 3,813 sepsis patients found that specific red blood cell distribution width (RDW) trajectories over the firs…
Tracking how your red blood cell size changes day by day reveals who is most likely to die from sepsis within 30 days.
Aspiration pneumonia linked to higher mortality and recurrence in Chinese geriatric cohort
Aspiration pneumonia linked to higher death and recurrence rates in older Chinese patients
A retrospective cohort study of 295 Chinese geriatric patients with pneumonia found aspiration pneumonia was associated with significantly h…
Older Chinese patients with aspiration pneumonia face much higher death and recurrence rates within three months compared to those with othe…
5-factor frailty index predicts postoperative pulmonary infection but not pneumothorax or effusion after lung resection
A Simple 5-Question Score Predicts Your Biggest Risk After Lung Surgery
This retrospective cohort study evaluated 391 patients undergoing lung resection to assess the association between 5-factor modified frailty…
A fast health check you can do in a clinic is surprisingly good at spotting who needs extra protection from infections after major lung surg…
Integrated clinical-imaging model predicts post-traumatic nonunion in long bone fractures
A New AI Tool Can Predict If Your Broken Bone Won't Heal
A retrospective cohort study of 343 patients with unilateral closed long bone fractures found that a gradient boosting machine model integra…
Doctors may soon use an artificial intelligence tool to give patients with serious bone fractures an early warning if their healing is at ri…
SARS-CoV-2 infection in singleton pregnant women increases antiphospholipid antibody prevalence and placental dysfunction risk
COVID in Pregnancy May Trigger Clot-Causing Antibodies
This prospective, observational cohort study examined singleton pregnant women without pre-existing complications who tested positive for SA…
Pregnant women who had COVID, especially in the third trimester, were more likely to test positive for antibodies tied to placental and clot…
Osteoarthritis diagnosis not independently linked to recurrent falls in OAI cohort study
Your Mood May Matter More Than Your Joints for Fall Risk
A retrospective cohort study of 4427 Osteoarthritis Initiative participants found that a new OA diagnosis was not independently associated w…
Older adults with knee or hip arthritis who feel down fall more often, and the emotional side of health may be the real driver.
qPCR shows higher MTB detection rate than AFB staining in granulomatous inflammation tissues
A Faster Way to Catch Hidden TB in Tissue Samples
A cohort study of 1,050 patients with granulomatous inflammation found qPCR had a higher MTB detection rate (63.43%) than AFB staining (26.2…
A modern DNA-based lab test is catching tuberculosis that the century-old stain has been missing — and it can flag drug resistance at the sa…
Mendelian randomization suggests potential causal link between severe COVID-19 and polymyositis risk
Severe COVID-19 May Set Off a Rare Muscle Disease, Genetic Study Hints
A single-center cohort study of 108 hospitalized COVID-19 patients used Mendelian randomization to explore associations with polymyositis.
A new genetic analysis adds to growing concern that severe COVID-19 can quietly trigger immune attacks on healthy muscle months later.
JSLE linked to higher CVD risk factors than JDM in adults with childhood-onset autoimmune diseases
Study compares heart health risks in adults with childhood-onset lupus or dermatomyositis
A single-centre longitudinal cohort study of 76 JSLE and 79 JDM adults found JSLE had higher hypertension, dyslipidaemia, and cholesterol le…
Adults with childhood lupus face higher heart risks like high blood pressure and cholesterol compared to those with juvenile dermatomyositis…