Sivelestat-containing regimens reduce all-cause mortality in sepsis-induced ARDS with OR 0.55
Sivelestat shows lower mortality for patients with sepsis and ARDS
This meta-analysis of 943 patients found that a sivelestat-containing regimen significantly reduced all-cause mortality in sepsis-induced AR…
A new review of data suggests the drug sivelestat may lower death rates for adults with severe lung and blood infections.
Protocol targets host-response biomarker accuracy for PJI in inflammatory arthritis
New plan to improve testing for joint infection in arthritis
This is a published protocol for a systematic review and diagnostic test accuracy meta-analysis, not a completed study. It will assess serum…
Doctors are planning a new way to better identify joint infections in patients with inflammatory arthritis using specific blood and fluid ma…
FDA Approves Jubbonti (denosumab) for Osteoporosis and Bone Loss Indications
FDA Approves Jubbonti, a Twice-Yearly Shot for Weak Bones
The FDA approved Jubbonti (denosumab), a RANKL inhibitor, for postmenopausal osteoporosis, osteoporosis in men, glucocorticoid-induced osteo…
The FDA approved Jubbonti (denosumab), a twice-yearly injection for people with weak bones at high risk of breaks. It treats osteoporosis in…
Dietary patterns and nutritional interventions may modify risk and inflammation in rheumatoid arthritis
Dietary Patterns May Help Manage Rheumatoid Arthritis Risks
This mini review examines the role of dietary patterns and targeted nutritional interventions in rheumatoid arthritis. The authors suggest n…
Specific dietary patterns and nutritional changes may help manage inflammation and other health risks for people living with rheumatoid arth…
Viral triggers and distinct molecular signatures characterize various white dot syndrome subtypes
Research reveals viral triggers and distinct markers for eye diseases
This narrative review synthesizes the clinical features and underlying mechanisms of white dot syndromes, including MEWDS, birdshot, and APM…
New research identifies specific viral triggers and unique biological markers for several rare conditions affecting the back of the eye.
Vision-language foundation models show inconsistent reporting of clinical metrics and limited interpretability in medical imaging
Audit Reveals Reporting Gaps in Medical Image AI Models
This narrative review with quantitative synthesis evaluates 50 original studies and 13 representative studies regarding vision-language foun…
A review of medical AI models shows that many key performance metrics are missing from research, making it harder to judge their clinical re…
Generative AI facilitates both the production and detection of health misinformation in clinical environments
Generative AI Impacts the Lifecycle of Health Misinformation
This narrative integrative review explores the role of generative artificial intelligence in the health misinformation lifecycle. It identif…
New research explores how generative AI can both create and detect health misinformation, impacting how people find and trust medical inform…
AKR1B10 may serve as a serum biomarker for AFP-negative hepatoblastoma subtypes
Scientists Explore Blood Marker Idea for Childhood Liver Cancer
This narrative review explores the potential of Aldo-keto reductase 1B10 (AKR1B10) as a biomarker for pediatric liver tumors. The authors su…
A new review suggests a protein called AKR1B10 might one day help spot some childhood liver cancers, but no patient data exist yet.
Impella CP improves survival in selected cardiogenic shock patients while routine early VA-ECMO lacks clear benefit
New data clarifies the role of heart pumps in shock
This narrative review examines the use of VA-ECMO and microaxial-pump strategies in patients with cardiogenic shock and ST-elevation myocard…
New research looks at how heart pumps and bypass machines help patients with severe heart damage after a heart attack.
Remimazolam's delirium prevention remains uncertain despite fewer hypotensive events than propofol
Remimazolam Shows Mixed Results for Preventing Postoperative Delirium
This narrative review examines remimazolam versus propofol for postoperative delirium in older surgical patients. It finds fewer hypotensive…
New research shows that while remimazolam may reduce low blood pressure, its ability to prevent delirium in older surgical patients is not y…
Lumbar Fractures as a Rare First Sign of Waldenström Macroglobulinemia
Rare Bone Fractures Linked to Waldenström Macroglobulinemia Identified
A systematic review found only 12 published cases of Waldenström macroglobulinemia first appearing as lumbar vertebral fractures.
New data identifies rare cases of lumbar vertebral fractures in patients with Waldenström macroglobulinemia, helping doctors distinguish the…
DTI may help predict prognosis and monitor recovery in lumbar disc herniation and stenosis
Imaging Technology May Help Predict Recovery from Lumbar Disc Herniation
This narrative review examines diffusion tensor imaging (DTI) for lumbar disc herniation and lumbar spinal stenosis. The authors argue DTI c…
New imaging techniques may help doctors predict how well patients will recover from back issues and track muscle changes after surgery.