PSMA-targeted radioligand therapy outcomes vary by patient characteristics and disease burden in metastatic castration-resistant prostate cancer
Prior chemo and liver spread worsen outcomes for prostate cancer patients on PSMA therapy
A systematic review and meta-analysis of 4,819 patients with metastatic castration-resistant prostate cancer reveals that prior chemotherapy…
A large review of 4,819 patients found that prior chemotherapy and liver spread worsen survival. This helps doctors predict who benefits mos…
Hypofractionated and dose-boosted radiotherapy improves metastasis-free survival in clinically localised prostate cancer
Dose-boosting radiotherapy may improve survival for high-risk prostate cancer patients
This systematic review and meta-analysis evaluated hypofractionated and dose-boosted radiotherapy fractionation schedules versus standard ra…
Combining external beam radiotherapy with brachytherapy or a focal boost significantly improved metastasis-free survival in patients with cl…
Liquid biopsy guides kidney-sparing decisions in upper tract urothelial carcinoma without replacing standard care
Liquid biopsy helps doctors decide on kidney-sparing care for upper tract urothelial carcinoma
This review discusses liquid biopsy-guided kidney-sparing management for patients with upper tract urothelial carcinoma. The authors note th…
A review shows liquid biopsy adds value to kidney-sparing decisions for upper tract urothelial carcinoma but does not replace standard imagi…
PSMA PET Parameters Predict Survival in mCRPC on Lu-PSMA-617
PSMA PET scan numbers may help predict Lu-PSMA therapy response in prostate cancer
Meta-analysis of 23 studies shows PSMA PET parameters, especially tumor volume, predict survival in mCRPC patients treated with Lu-PSMA-617.
A meta-analysis of 23 studies suggests certain PSMA PET scan measurements might help predict how patients with metastatic prostate cancer re…
AI assistance improves diagnostic accuracy for clinically significant prostate cancer detection via MRI in this systematic review
AI assistance improves MRI accuracy for finding significant prostate cancer
A meta-analysis of 29 studies involving 7,398 patients demonstrates that AI assistance significantly boosts sensitivity, specificity, and pr…
A new analysis of 29 studies shows AI help boosts MRI accuracy for prostate cancer, helping doctors spot the right cases without missing any…
Systematic review analyzes renal hematoma risks following ureteroscopy and retrograde intrarenal surgery procedures in large patient cohorts
Surgery for kidney stones carries a small but real risk of bleeding
A comprehensive meta-analysis of 23,258 patients reveals a pooled subcapsular renal hematoma incidence of 0.42%. Fever emerges as the strong…
A large review found that kidney stone surgery causes bleeding in less than one percent of patients, with one method showing slightly higher…
Fluoroless ultrasound-guided techniques lower complications in percutaneous nephrolithotomy with equivalent stone-free rates
Fluoroless ultrasound guidance reduces complications during kidney stone surgery
This systematic review and meta-analysis of randomized studies evaluated fluoroless ultrasound-guided versus fluoroscopy-guided techniques f…
A meta-analysis of randomized trials shows that using ultrasound instead of X-ray guidance lowers overall complications for kidney stone rem…
Local anaesthetic transperineal biopsy reduces infection and sepsis while improving cancer detection compared to transrectal ultrasonography methods
New biopsy method finds fewer infections and more cancer than standard approach
A systematic review of 8,497 patients found that local anaesthetic transperineal biopsy significantly lowers infection and sepsis risks. Thi…
A large analysis shows transperineal prostate biopsies cause fewer infections and detect more cancer than the traditional transrectal method…
64 Cu-PSMA-617 shows highest detection rates in biochemically recurrent prostate cancer
PSMA PET scans find prostate cancer better than older tests
This systematic review and network meta-analysis of PSMA PET tracers in prostate cancer found that 64 Cu-PSMA-617 had the highest detection …
New PSMA PET scans find prostate cancer more often than older tests. One type, 64 Cu-PSMA-617, found the most cancers.
Metachronous non-muscle invasive bladder cancer after UTUC has worse recurrence and progression with BCG than primary disease
Doctors found that bladder cancer returning later has higher risk of coming back again
This systematic review and meta-analysis of 1292 patients found that metachronous non-muscle invasive bladder cancer after upper tract uroth…
A large review shows bladder cancer returning after a previous kidney cancer treatment is more likely to grow back. This group also has a lo…
ECIRS triples stone-free odds versus PCNL in large kidney stones, meta-analysis finds
New surgery clears kidney stones better than the standard method without more risk
This systematic review and meta-analysis of 1988 patients with high stone burden found that endoscopic combined intrarenal surgery (ECIRS) s…
A new analysis shows a specific surgery clears kidney stones faster and with fewer complications than the standard approach for tough cases.
Intensity-modulated radiotherapy reduces acute and delayed G2+GI toxicities versus 3D-CRT in high-risk prostate cancer
Post hoc analysis shows IMRT reduces radiation side effects for high-risk prostate cancer
This post hoc analysis of a Phase III randomized controlled trial evaluated intensity-modulated radiotherapy (IMRT) versus three-dimensional…
A post hoc analysis of a Phase III trial found that intensity-modulated radiotherapy reduced radiation side effects compared to older techni…