HER2 overexpression significantly associates with higher grade, progression, and lymph node metastasis in bladder cancer
HER2 Overexpression Linked to Higher Risk in Bladder Cancer
This meta-analysis of 2799 patients with urothelial carcinoma of the bladder identifies significant associations between HER2 overexpression…
New research links HER2 protein levels to more aggressive features and higher recurrence rates in patients with bladder cancer.
Subcapsular orchiectomy yields higher treatment satisfaction but less hormonal and PSA suppression than total orchiectomy
Subcapsular orchiectomy leads to higher patient satisfaction in prostate cancer
This meta-analysis of 759 patients with advanced prostate cancer compared subcapsular orchiectomy to total orchiectomy. Findings indicate su…
Men with advanced prostate cancer may report higher treatment satisfaction with subcapsular orchiectomy despite higher hormone and PSA level…
HIFU associated with superior erectile function and urinary continence compared to RARP in localized prostate cancer
HIFU treatment shows better sexual and urinary function in prostate cancer
This meta-analysis of 2123 patients compared high-intensity focused ultrasound (HIFU) to robot-assisted radical prostatectomy (RARP) for loc…
A new look at treatment options shows that high-intensity focused ultrasound may preserve more physical function than surgery for prostate c…
Standard-of-care salvage radiotherapy aims to improve metastasis-free proportion in biochemical recurrence of prostate cancer
New trial plans to test radiation for prostate cancer recurrence
This randomized controlled trial protocol evaluates standard-of-care salvage radiotherapy versus initial observation in 312 men with biochem…
Doctors are planning a trial to see if early radiation helps men whose prostate cancer returns after surgery but cannot be seen on scans.
Multi-protein panels improve gastric cancer diagnosis over single markers
Protein Microarrays Show Better Diagnostic Performance for Gastric Cancer
This systematic review examines protein microarray-based proteomics in gastric cancer. It finds that multi-protein biomarker panels and comp…
New protein microarray methods may provide more accurate gastric cancer diagnoses than traditional single-marker tests by using multi-protei…
Thiazolidinediones increase bladder cancer risk while SGLT2 inhibitors show potential protective effects in Type 2 Diabetes
Diabetes medications show different links to bladder cancer risk
This meta-analysis of 85 studies evaluated the association between various antidiabetic medications and bladder cancer risk in patients with…
New data shows that while some diabetes medications may increase bladder cancer risk, others might offer a protective effect.
Cold atmospheric plasma modulates immune signaling pathways and macrophage polarization in infection and cancer models
Cold atmospheric plasma may help fight infection and heal wounds
This narrative review synthesizes evidence on cold atmospheric plasma (CAP) and its impact on immune signaling, including NF-kB, Nrf2-Keap1,…
Cold atmospheric plasma could offer new ways to treat infections, heal wounds, and manage inflammation by influencing the immune system.
Interactive digital assistants may improve short-term HPV vaccine booking and cervical cancer screening uptake
Digital assistants may help people complete cervical cancer screenings
This systematic review of 14 reports evaluated interactive patient-facing digital assistants for HPV vaccination and cervical cancer screeni…
Interactive digital tools like chatbots and health apps can help more people book HPV vaccine appointments and complete cervical cancer scre…
AI diagnostic tools show pooled AUC of 0.845 in prostate cancer, deep learning outperforms classical models
AI Tools Show Promise for Prostate Cancer Diagnosis and Prognosis
This meta-analysis of 43 studies (34 in the meta-analysis) evaluated AI-based tools for prostate cancer diagnosis and prognosis. Pooled AUCs…
New analysis shows AI models may improve the accuracy of diagnosing and predicting the outcome of prostate cancer cases.
Gut dysbiosis is associated with prostate enlargement and lower urinary tract symptoms in BPH
Gut Microbiota May Be Linked to Prostate Enlargement Symptoms
This narrative review explores the potential link between gut microbiota and benign prostatic hyperplasia (BPH). The authors synthesize evid…
New research suggests a link between gut bacteria imbalances and symptoms of an enlarged prostate, offering a potential new area for future …
Holmium laser fragmentation and laparoscopic excision treat urachal calculus in a 54-year-old man
Doctors find bladder stone caused by a rare remnant tissue
This case report with literature review describes a 54-year-old man with a urachal calculus at the bladder dome, treated with holmium laser …
A man with a calcified mass at the top of his bladder revealed that it was actually an old, inflamed piece of tissue.
FH-deficient renal cell carcinoma case shows rapid bone metastasis despite adjuvant therapy
Rare Kidney Cancer Case Shows Aggressive Spread Despite Treatment
This case report and literature review describes a 42-year-old woman with FH-deficient renal cell carcinoma and uterine leiomyomas, treated …
A rare kidney cancer in a 42-year-old woman spread quickly despite surgery and therapy, highlighting the need for early genetic testing.