STING activation targets renal, prostatic, and cancer inflammation in mini-review
The Immune Alarm System in Your Kidneys and Prostate Has a Dark Side
This mini-review discusses STING activation as a potential intervention for renal inflammation, prostatic inflammation, and cancer. The popu…
A molecular alarm in kidneys and prostate that fights infection can get stuck on, driving chronic inflammation, scarring, and cancer risk.
Surgical smoke from robot-assisted radical cystectomy contained no detectable bladder cancer cells, mutations, or exosomes
Surgical Smoke Does Not Carry Bladder Cancer Cells
This laboratory investigation evaluated whether surgical smoke generated during robot-assisted radical cystectomy (RARC) for bladder cancer …
Smoke from robot bladder surgery does not carry cancer cells, genes, or exosomes, ending a long-standing patient fear about this common proc…
Minimum immunobiology packages may improve kidney transplant safety and equity in low- and middle-income settings.
Sri Lanka Shows How Safer Kidney Transplants Are Possible Anywhere
This narrative review examined kidney transplantation practices in low- and middle-income settings, specifically Sri Lanka. It evaluated a m…
A new roadmap helps low-resource hospitals match wealthy countries' kidney transplant results using simple lab tools.
Conference report reviews EU Regulation 2019/6 impact on animal health innovation stakeholders in Munich.
Will new EU rules help or hurt animal health innovation?
This conference report examines the impact of Regulation (EU) 2019/6 and associated legislation on innovation within the animal health secto…
Experts in Munich gathered to discuss how new EU veterinary rules might support or hinder innovation for pets and livestock.
Hexaminolevulinate blue light cystoscopy detects more bladder cancer lesions than white light cystoscopy in a Chinese phase III study.
A Special Blue Light Catches Bladder Cancer Standard Scopes Miss
This prospective, comparative, within-patient controlled multicenter phase III bridging study enrolled 158 patients with bladder cancer in C…
A special blue-light scope caught bladder cancer in 43% of patients that standard white-light scopes missed during screening.
Topical anesthesia reduces catheter-related bladder discomfort and urethral pain after ureteroscopy lithotripsy in male patients.
A Simple Gel Applied Before Catheter Insertion Cuts Post-Surgery Pain
A single-center randomized controlled study of 330 patients undergoing ureteroscopy lithotripsy and urinary catheterization found that topic…
A numbing gel applied before catheter insertion may dramatically reduce the burning, urgent bladder discomfort that troubles many patients a…
SRSF1 haploinsufficiency in 17q22 deletion syndrome explains nuchal pellucida thickening and neurodevelopmental outcomes.
One Tiny Missing Gene Behind a Rare 17q22 Syndrome
This meta-analysis and systematic review evaluated 25 cases involving 17q22 deletion syndrome, including one fetus with nuchal pellucida thi…
A single missing gene called SRSF1 likely causes the brain and vision problems seen in 17q22 deletion syndrome, helping families understand …
Multimodal AI may outperform unimodal systems for disease diagnosis, review suggests
When One Scan Is Not Enough for a Real Diagnosis
A systematic review suggests multimodal artificial intelligence systems may address limitations of unimodal AI in disease diagnosis, which o…
Medicine rarely lives in one data type, and AI models that combine many types tend to be more reliable than those trained on just one.
AI model shows high accuracy for prostate cancer and prostatitis detection on MRI in retrospective cohort
AI models showed promise in detecting prostate conditions but need more testing
A retrospective cohort study of 153 patients with prostate cancer or prostatitis found that a Faster R-CNN model achieved 96% accuracy for P…
AI models matched expert doctors in reading prostate MRI scans but missed smaller cancer lesions, showing promise that needs more testing be…
One-stage RIRS for renal stones shows longer operative time after prior PCNL in retrospective cohort
Does past kidney stone surgery affect your next one?
A retrospective cohort study of 115 patients with renal stones undergoing one-stage RIRS found that those with a history of PCNL had signifi…
Past kidney stone surgery doesn't increase risks or hospital stays, but prior PCNL does lengthen the next operation by about eight minutes.
Machine learning algorithms predicted stroke risk with high accuracy in a large retrospective cohort.
New AI models may help predict stroke risk better than current methods in large data reviews
This retrospective multicenter study evaluated multiple machine learning algorithms, including random forest, against established models for…
A new computer model predicts stroke risk better than current methods, achieving a high accuracy score in a review of over 35,000 patients.
Ga-PSMA-11 PET/CT shows high sensitivity for local prostate cancer but lower for lymph nodes in phase 1/2 trial.
Imaging test shows promise for detecting prostate cancer spread in early trial
A prospective phase 1/2 single-arm trial in 173 high-risk prostate cancer patients found Ga-PSMA-11 PET/CT had 0.971 sensitivity for local d…
A new imaging test found prostate cancer in lymph nodes for 56% of patients, leading doctors to cancel surgery for 13% and adjust radiation …