Metachronous non-muscle invasive bladder cancer after UTUC has worse recurrence and progression with BCG than primary disease
Doctors found that bladder cancer returning later has higher risk of coming back again
This systematic review and meta-analysis of 1292 patients found that metachronous non-muscle invasive bladder cancer after upper tract uroth…
A large review shows bladder cancer returning after a previous kidney cancer treatment is more likely to grow back. This group also has a lo…
ECIRS triples stone-free odds versus PCNL in large kidney stones, meta-analysis finds
New surgery clears kidney stones better than the standard method without more risk
This systematic review and meta-analysis of 1988 patients with high stone burden found that endoscopic combined intrarenal surgery (ECIRS) s…
A new analysis shows a specific surgery clears kidney stones faster and with fewer complications than the standard approach for tough cases.
Intensity-modulated radiotherapy reduces acute and delayed G2+GI toxicities versus 3D-CRT in high-risk prostate cancer
Post hoc analysis shows IMRT reduces radiation side effects for high-risk prostate cancer
This post hoc analysis of a Phase III randomized controlled trial evaluated intensity-modulated radiotherapy (IMRT) versus three-dimensional…
A post hoc analysis of a Phase III trial found that intensity-modulated radiotherapy reduced radiation side effects compared to older techni…
HER2 overexpression rare in prostate cancer but linked to higher Gleason score and stage
Nearly half of prostate cancer cases show some HER2 activity, but high levels are rare
This systematic review and meta-analysis of 1258 prostate carcinoma cases found HER2 Score 3 overexpression in only 4.9% of cases, but non-n…
A large review found that nearly half of prostate cancer cases show some HER2 activity, while only a small fraction have high levels.
MRI-based risk calculators improve discrimination for clinically significant and all prostate cancer compared to traditional models
New MRI tools improve prostate cancer detection accuracy compared to standard methods
This systematic review and meta-analysis evaluated MRI-based risk calculators versus traditional clinical risk calculators in prostate cance…
New MRI-based risk calculators show better accuracy than traditional tools for spotting clinically significant prostate cancer, potentially …
Micro-ultrasound sensitivity 0.84 and specificity 0.41 for prostate cancer in five prospective studies
Micro-ultrasound helps find prostate cancer when MRI is not available
This systematic review and diagnostic test accuracy meta-analysis synthesized evidence from five prospective studies on standalone 29-MHz mi…
A meta-analysis shows standalone micro-ultrasound can help rule out prostate cancer, especially when MRI is unavailable or delayed.
Meta-analysis of RCTs shows mPCNL yields higher single-session stone-free rates than RIRS for medium renal stones
Mini-PCNL clears kidney stones better than RIRS in one session
This meta-analysis of randomized controlled trials evaluated retrograde intrarenal surgery versus miniaturized percutaneous nephrolithotomy …
Mini-PCNL clears medium-sized kidney stones in one session more often than RIRS, but RIRS has fewer complications and shorter hospital stays…
Narrative review covers diagnostic and treatment strategies for metastatic head and neck cancer with no identifiable primary tumor
Doctors use many tools to treat head and neck cancer when the main tumor is hidden
This narrative review addresses diagnostic and treatment strategies for metastatic cases of head and neck cancer with no identifiable primar…
When head and neck cancer spreads but the original spot is missing, doctors use many tools. Imaging, special tests, and surgery help find th…
Meta-analysis reveals complex links between endocrine therapy and fertility worries in cancer patients of childbearing age
Depression and endocrine therapy linked to fertility worries in cancer patients of childbearing age
A systematic review of 3,282 patients found depression, higher education, and endocrine therapy linked to fertility concerns. Conversely, ma…
A review of 3282 cancer patients found depression, endocrine therapy, and full-time work linked to fertility concerns, while marriage and ha…
Review examines health risks of dog-worn equipment and calls for safer practices
Dog Collars May Harm Eyes and Throat More Than We Knew
This narrative review addresses the health implications and risks associated with dog-worn equipment such as collars and harnesses. The auth…
• Common collars might silently strain dog eyes and throats • Helps owners choose safer gear right now • Real proof needs more research but …
Systematic review and meta-analysis reports TFL lithotripsy complication rates in urolithiasis
New laser tool breaks kidney stones with fewer serious side effects
This systematic review and meta-analysis of 3,329 patients with urolithiasis found a pooled overall complication rate of 10.42% for Thulium …
A new laser tool breaks kidney stones with fewer serious side effects and high success rates for most patients
Narrative review of lung, breast, liver, and kidney cancer evidence
New Cancer Tests Could Spot Tumors Years Earlier Than Before
This narrative review synthesizes published English-language evidence on lung, breast, liver, and kidney cancers. The authors note the scope…
A new wave of cancer biomarker tests can spot lung, breast, liver, and kidney tumors years earlier, opening the door to faster treatment and…