Dutasteride-Tadalafil FDC Shows Superior Symptom Reduction in BPH Phase III Trial
Does taking two prostate drugs together work better than just one for symptom relief?
A phase III randomized trial in 619 BPH patients found a fixed-dose combination (FDC) of dutasteride 0.5 mg/tadalafil 5 mg significantly imp…
Men taking two prostate drugs together saw symptom relief twice as fast as single-drug therapy, though they faced more side effects.
Audit plus peer comparison improved documentation of tumour features and resection completeness in non-muscle-invasive bladder cancer surgery
Audit and feedback improved documentation of bladder cancer surgery details in a large trial
This cluster randomised controlled trial involved 14,915 patients undergoing transurethral resection of bladder tumour surgery across 201 si…
This large study examined whether adding peer comparison and education to standard audits changed how bladder cancer surgery was performed.
Targeted plus perilesional biopsy noninferior to combined biopsy for prostate cancer detection
Could a simpler prostate biopsy find dangerous cancers just as well?
A single-center RCT in 380 biopsy-naïve patients with a single unilateral suspicious MRI lesion found targeted plus perilesional biopsy (TPL…
A simpler prostate biopsy found dangerous cancers just as well as the standard method while causing less pain and bleeding for men with susp…
Prior HoLEP association with longer operative time and catheter duration in subsequent RARP
Does prior prostate surgery make your next operation harder or riskier?
This systematic review and meta-analysis of three retrospective studies compared men undergoing robot-assisted radical prostatectomy (RARP) …
Prior prostate surgery makes the next operation take longer and requires more rebuilding, but cancer removal and recovery remain just as eff…
ThuFLEP shows early safety, high catheter-free rate in small BPH cohort
Can a new laser procedure help men with enlarged prostates get home faster?
A prospective cohort study of 32 men with BPH undergoing ThuFLEP found no Clavien-Dindo grade ≥3 complications and an 87.5% catheter-free ra…
A new laser prostate surgery helped 88% of men go home without a catheter the next day and eliminated all catheters within two weeks.
Phase 2 trial of muscadine grape extract added to ADT for recurrent prostate cancer fatigue
Muscadine grape extract studied for fatigue in men with recurrent prostate cancer
A Phase 2 randomized controlled trial enrolled 106 men with recurrent prostate cancer on androgen deprivation therapy to test muscadine grap…
Men with recurrent prostate cancer taking hormone therapy may feel less extreme fatigue when adding a natural muscadine grape extract supple…
Small cell prostate cancer presents with metastases in 71.7% of cases, SEER analysis finds
Study finds most small cell prostate cancer cases spread at diagnosis
A retrospective cross-sectional analysis of 541 patients with microscopically confirmed small cell carcinoma of the prostate (SCCP) from SEE…
Most small cell prostate cancer cases have already spread to other parts of the body by the time patients are diagnosed, with bone and liver…
Meta-analysis finds high complication rates after UroLume endoprosthesis implantation
What happens when a urethral implant fails? New analysis reveals high complication rates
A preprint meta-analysis of 43 studies involving 3847 patients with UroLume procedures found pooled complication rates of 37.9% for restenos…
A urethral implant once marketed as a permanent fix has left thousands with irreversible damage, chronic pain, and severe psychological dist…
Neoadjuvant sacituzumab govitecan plus pembrolizumab shows 39% clinical complete response in MIBC
Drug combination shows promise for bladder cancer patients who cannot take standard chemotherapy
A single-arm phase 2 study of 49 patients with muscle-invasive bladder cancer ineligible for cisplatin found a clinical complete response ra…
A new drug combination helped 39% of bladder cancer patients who couldn't take standard chemotherapy achieve a complete response before surg…
SMART radiation shows 90% 4-year local control in small oligometastatic abdominopelvic cohort
Can targeted radiation safely treat small, recurring cancer spots in the abdomen?
A single-arm Phase 1/2 trial in 10 patients with solid tumor abdominopelvic oligometastases found Stereotactic MR-Guided Adaptive Radiation …
Targeted radiation safely controlled small recurring cancer spots in the abdomen for 90% of patients with only mild side effects after four …
Expert panel agrees on early detection and ARPI/ADT role for high-risk prostate cancer BCR
Experts agree on some approaches for high-risk prostate cancer recurrence but disagree on timing
An expert opinion review summarized panel discussions on managing high-risk biochemical recurrence in prostate cancer.
Experts agree on early detection and medication use for high-risk prostate cancer recurrence but disagree on the best timing for starting tr…
Immunocompromised herpes zoster patients with CNS infection show higher encephalitis incidence and worse prognosis
For shingles patients with brain infections, does a weakened immune system make things worse?
A retrospective cohort study of 166 herpes zoster patients with VZV-associated CNS infection found immunocompromised patients had significan…
Shingles patients with weakened immune systems face higher risks of severe brain inflammation and worse outcomes when treatment is delayed.