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Suction-assisted PCNL maintains lower intrarenal pressure and improves perioperative outcomes compared to conventional PCNLSuction Assisted Surgery May Lower Pressure During Kidney Stone Removal

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Key Takeaway
Consider suction-assisted PCNL to achieve lower intrarenal pressure and improved perioperative outcomes in nephrolithiasis.

This meta-analysis evaluates the efficacy of suction-assisted percutaneous nephrolithotomy (PCNL) compared to conventional PCNL for patients with nephrolithiasis. The analysis included 1,171 patients and focused on intrarenal pressure (IRP), surgical outcomes, and postoperative complications.

The synthesis indicates that suction-assisted PCNL maintains significantly lower IRP, specifically avoiding prolonged episodes of 30 mmHg, with values ranging from 2.7 to 16.9 mmHg compared to 15.4 to over 30 mmHg in conventional groups. Additionally, the suction-assisted group showed shorter operative times, shorter hospital stays, and higher stone-free rates. Significant reductions were also noted for postoperative fever and Clavien-Dindo 2 complications.

A reduction in sepsis risk was suggested by pooled analysis, though the authors note that confidence intervals were wide due to low event rates. The study notes that while suction-assisted PCNL appears to offer superior IRP control and more favorable perioperative outcomes, the evidence is not yet definitive. The authors conclude that more high-quality randomized controlled trials are necessary to confirm these associations.

How this fits prior evidence

This meta-analysis addresses gaps in procedural optimization for nephrolithiasis by comparing suction-assisted PCNL to conventional methods. It complements existing evidence regarding stone-free rates and surgical choices, such as the findings that mPCNL yields higher single-session stone-free rates than RIRS for medium renal stones and that RIRS with TFLLT shows similar stone-free rates to PNL for 20-30 mm kidney stones.

Researchers analyzed data from 1,171 patients undergoing a procedure called percutaneous nephrolithotomy (PCNL) to treat large kidney stones. The study compared a standard method with a version that uses suction assistance during the surgery.

The results showed that the suction-assisted method kept internal pressure significantly lower than the conventional method. This helped prevent high-pressure spikes during the procedure. Additionally, patients who had the suction-assisted surgery were less likely to experience postoperative fever or specific surgical complications. The study also noted shorter operation times and shorter hospital stays for these patients.

While the results are promising, there is some uncertainty regarding the risk of sepsis because very few cases occurred in the study. Because this was a meta-analysis rather than a new trial, more high-quality randomized controlled trials are needed to confirm these findings. Patients should discuss these specific surgical techniques with their urologist to see if it is appropriate for their condition.

What this means for you:
Suction-assisted surgery may lower kidney pressure and reduce complications, but more large trials are needed.

Common questions

How does suction-assisted surgery help with kidney stones?

Suction-assisted PCNL helps by maintaining significantly lower intrarenal pressure compared to conventional methods. It prevents prolonged episodes of high pressure, which can reach over 30 mmHg in traditional procedures. This method also showed higher stone-free rates and shorter hospital stays for patients.

Are there fewer complications with the suction method?

The study found significantly lower risks of postoperative fever and specific surgical complications (Clavien-Dindo 2 or more) in the suction-assisted group. While it suggested a lower risk of sepsis, the data for that specific finding was less certain due to low event rates.

Is this technique proven to be better than standard surgery?

The study shows a link between suction-assisted PCNL and better outcomes like lower pressure and shorter operation times. However, because the evidence comes from a meta-analysis with some wide confidence intervals, more high-quality randomized controlled trials are needed to confirm these benefits.

Study Details

Study typeMeta analysis
Sample sizen = 1,171
EvidenceLevel 1
PublishedJul 2026
View Original Abstract ↓
OBJECTIVE: Elevated intrarenal pressure (IRP) during percutaneous nephrolithotomy (PCNL) is linked to postoperative infectious morbidity. This systematic review and meta-analysis evaluated suction-assisted PCNL versus conventional PCNL regarding IRP and clinical outcomes. METHODS: Registered in PROSPERO (CRD420251235580), this study followed PRISMA guidelines. Primary outcome was IRP; secondary outcomes included postoperative fever, sepsis, Clavien-Dindo ≥ 2 complications, operative time, hospital stay, and stone-free rate. Random-effects models and I2 statistics were used. Bias was assessed via Cochrane ROB-2 and ROBINS-I tools. RESULTS: Eight studies involving 1,171 patients (577 suction-assisted; 594 conventional) were included. Quantitative synthesis of six studies showed suction-assisted PCNL maintained significantly lower IRP (2.7-16.9 mmHg) compared to conventional groups (15.4 to > 30 mmHg), effectively preventing prolonged episodes of ≥ 30 mmHg. Suction-assisted PCNL was associated with significantly lower risks of postoperative fever and Clavien-Dindo ≥ 2 complications. Pooled analysis suggested reduced sepsis risk, though confidence intervals were wide due to low event rates. Suction cohorts reported no pressure-related severe infections. Additionally, suction-assisted PCNL demonstrated shorter operative times, shorter hospital stays, and higher stone-free rates. Heterogeneity was low to moderate across most outcomes. CONCLUSIONS: Suction-assisted PCNL provides superior IRP control and more favorable perioperative outcomes than conventional PCNL. While these systems appear to reduce infectious morbidity and complications, additional high-quality randomized controlled trials are required for confirmation.
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