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Phase 2 N=389 Randomized Triple-blind Treatment

Effects of Magnesium on Individuals Undergoing Coronary Artery Bypass Graft Surgery

Coronary Disease · Heart Diseases · Cardiovascular Diseases · Neurologic Manifestations

Enrolled (actual)
389
Serious AEs
17.7%
Results posted
Oct 2012
Primary outcome: Primary: Cognitive Function — 0.07; 0.12 Continuous cognitive change score

Study Design & Population

Study type
Interventional
Phase
Phase 2
Interventions
Magnesium (Drug); 0.9% saline (Drug)
Age
Adult, Older Adult · 55+ yrs
Sex
All
Sponsor
Duke University
Primary completion
May 2009

Outcome Measures

OutcomeResultp-value
PRIMARY
Cognitive Function
0.07; 0.12

Summary

The purpose of this study is to examine the effects of supplemental magnesium on the neurocognitive function of individuals undergoing coronary artery bypass graft (CABG) surgery.

Eligibility Criteria

Inclusion Criteria

  • Coronary heart disease

Exclusion Criteria

  • Early dementia
  • History of psychiatric illness
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00041392). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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