Questions about Heart Failure
Can natriuresis-guided protocols help with weight loss in acute decompensated heart failure?
Yes, natriuresis-guided protocols increase weight loss in acute decompensated heart failure, with a meta-analysis showing about 0.45 kg more weight loss at 48 hours compared to standard care.
Full answer →Are SGLT2 inhibitors effective for treating heart failure with mildly reduced ejection fraction?
Yes, SGLT2 inhibitors are effective for treating heart failure with mildly reduced ejection fraction, reducing heart failure hospitalizations and improving outcomes.
Full answer →Does finerenone help patients with heart failure with mildly reduced ejection fraction?
Yes, finerenone reduces cardiovascular death and worsening heart failure events in patients with heart failure with mildly reduced ejection fraction, based on a network meta-analysis and the FINEARTS-HF trial.
Full answer →Can erythropoiesis-stimulating agents help adults with chronic heart failure and anaemia?
Erythropoiesis-stimulating agents (ESAs) reduce total heart failure hospitalizations and improve exercise tolerance in adults with chronic heart failure and anaemia, but do not lower mortality risk.
Full answer →Do alternative loop diuretics reduce hospitalizations for patients with chronic heart failure?
No, alternative loop diuretics (torsemide, azosemide, piretanide) do not reduce hospitalizations compared to furosemide in chronic heart failure, based on a systematic review of 23 trials.
Full answer →What are the main themes in coping experiences for chronic heart failure patients and caregivers?
Coping experiences for CHF patients and caregivers center on differing views of illness, emotional exhaustion, strained relationships, and a need for support to find new meaning.
Full answer →Does taking Qishen Yiqi dropping pills plus Western medicine improve chronic heart failure efficacy?
A 2024 trial found that adding Qishen Yiqi dropping pills to standard Western medicine improved clinical effectiveness and heart function in chronic heart failure patients.
Full answer →Does having higher levels of EPA in my blood increase my risk of ischemic heart disease?
Higher EPA levels may slightly increase ischemic heart disease risk, according to genetic studies, but the evidence is not definitive.
Full answer →All Heart Failure Articles
- Spironolactone reduces cardiovascular risk in heart failure with preserved ejection fraction regardless of eGFR decline
- Plasticisers disrupt the hypothalamic-pituitary-thyroid axis and potentially contribute to cardiovascular dysfunction
- Intradialytic exercise improves cardiovascular function and arterial stiffness in patients on maintenance haemodialysis
- Four mailer types aim to increase health care proxy documentation in patients with chronic conditions
- Rheumatic heart disease prevalence in Nepal is 3.1% with significant geographic and temporal disparities
- Geographic and socioeconomic disparities limit access to mechanical circulatory support and heart transplantation
- Breviscapine Add-On May Improve Angina Response in Coronary Heart Disease
- High-flow nasal cannula shows no significant difference from noninvasive ventilation in acute heart failure
- MASLD linked to 35% higher odds of HFpEF in pooled analysis of 899,629 patients
- Disulfidptosis may drive cardiomyocyte injury and cytoskeletal collapse under conditions of disulfide stress
- Culturally tailored meal programs reduce hospitalization rates among patients with heart failure
- Conduction system pacing reduces heart failure hospitalization and cardiomyopathy risk compared to right ventricular pacing
- Tai Chi provides positive effects for balance, mood, and cognitive performance in older adults
- Sarcopenia and Low Grip Strength Correlate with Increased Cardiovascular Risk in Older Adults
- Semaglutide reduces NT-proBNP levels and heart-failure hospitalization in adults with HFpEF and obesity
- Calcium overload drives heart failure progression; restoring calcium cycling may reverse remodeling
- Programmed intermittent boluses of ropivacaine do not reduce opioid consumption compared to continuous infusion
- Stroke prevalence 14% after LVAD, highest in Asia, projected to decline
- Left bundle branch pacing improves CRT response and reduces mortality in heart failure patients
- GLP-1 receptor agonists reduce MACE (HR 0.69) and all-cause mortality (HR 0.67) in Type 2 Diabetes
- GLP-1 RA and SGLT2i combination therapy reduces mortality and hospitalization in heart failure
- NYHA class and left ventricular ejection fraction are robust predictors of sudden cardiac death in heart failure
- Early integration of palliative care improves spiritual well-being in heart failure patients with LVEF > 40%
- GLP-1 Receptor Agonists Reduce Mortality and Hospitalization in Heart Failure with Preserved Ejection Fraction
- Multidisciplinary Palliative Rehabilitation Improves Quality of Life in Advanced Life Limiting Illness
- MDS patients have 6.2 times higher cardiovascular disease prevalence than the general population
- Double-chambered left ventricle in adulthood with severe mitral regurgitation and refractory heart failure
- Early extubation reduces mortality and complications in adults undergoing cardiac surgery
- Genetic cause identified in fewer than half of congenital heart disease cases
- Speckle-tracking echocardiography parameters show growing evidence of utility in predicting cardiac resynchronization therapy response
- AIM-CHD system improves LDL-C target attainment to 71% in coronary heart disease patients
- Eight traditional Chinese medicine injections combined with conventional medicine improve outcomes in post-AMI heart failure
- AI agent systems may improve cardiovascular outcomes and clinical documentation efficiency in heart failure
- Genetic risk scores for Primary Aldosteronism identify blood pressure independent pathways for cardiovascular disease
- Reduced-dose daratumumab and bortezomib may achieve partial renal remission in CyBorD-refractory PGNMID
- Ultra-fast-track anesthesia may reduce invasive ventilation duration and ICU resource use in selected cardiac patients
- Digital health technologies improve 6-minute walk distance by MD 18.74 m in chronic heart failure
- Cognitive frailty prevalence reaches 32% among older adults with heart failure
- Heart transplant recipients show high trust in clinician-guided digital tools for health monitoring
- Comprehensive self-management behavior interventions improve scores in older adults with coronary heart disease and diabetes
- Survivors of pediatric heart failure surgeries face significant neurodevelopmental and neurocognitive difficulties
- Gene, inflammation, and metabolic dysregulation drive pathophysiology in pediatric dilated cardiomyopathy
- Sacubitril/valsartan associated with improved renal outcomes in patients with heart failure
- CCTA imaging biomarkers provide multidimensional cardiovascular risk stratification for coronary heart disease and atrial fibrillation
- Gut-derived metabolites influence myocardial mitochondrial homeostasis and inflammatory signaling in heart failure
- Gut microbiota and metabolites communicate bidirectionally with the host cardiovascular system via metabolic networks
- Beta-blocker therapy shows variable outcomes for myocardial infarction patients based on ejection fraction
- Sex and gender differences impact heart failure symptoms, quality of life, and treatment access
- Bortezomib, cyclophosphamide, and dexamethasone achieved remission in a patient with AL amyloidosis and POEMS syndrome
- Higher serum total bilirubin levels associated with lower long-term risk in coronary heart disease patients
- Targeting protein acylation modifications via SIRT1 and HDACs may mitigate myocardial injury and inflammation
- GLP-1 receptor agonists and tirzepatide provide cardiovascular benefits across multiple clinical scenarios
- Percutaneous transcatheter closure using an Amplatzer Muscular VSD Occluder treats left ventricular pseudoaneurysm
- Neural-immune-cardiovascular axis emerges as therapeutic target in atherosclerosis, hypertension, heart failure
- Remote cardiac rehabilitation supported by mHealth improves exercise capacity in patients with heart failure
- Cognitive impairment affects 39% of chronic heart failure patients in pooled analysis
- Unified cardiometabolic disease framework links T2DM, ASCVD, HFpEF, MASLD, hypertension, and CKD via shared pathophysiology
- Persistent insomnia in heart failure is associated with higher anxiety and lower functional capacity
- GLP-1 receptor agonists reduce HF worsening events in HFpEF but show no benefit in HFrEF
- MAGGIC Score Predicts Mortality Outcomes in Patients Undergoing Mitral Valve Transcatheter Edge to Edge Repair
- Patients with cardiovascular diseases show measurable prevalence of active cancer across multiple conditions
- Macrophage migration inhibitory factor serves as a potential biomarker and therapeutic target for atrial fibrillation
- Health literacy is moderately associated with improved self-care behaviors in patients with multiple chronic diseases
- Minimally invasive pulse wave analysis exceeds 30% error threshold for cardiac output and index
- Acupuncture combined with exercise rehabilitation improves cardiac function and walk distance in heart failure
- Vagal nerve stimulation did not meet the primary endpoint of reduced cardiovascular death or HF hospitalization
- ICM-guided congestion management shows no difference in arrhythmia occurrence rates for heart failure patients
- Continuous intravenous furosemide improves freedom from congestion compared to intermittent bolus administration
- Dapagliflozin 10 mg daily maintains consistent diuretic effects regardless of eGFR levels in acute heart failure
- Demographic and clinical factors associated with poststroke cognitive impairment in stroke patients
- Beta-blocker use associated with lower mortality risk in heart failure with preserved ejection fraction
- Sacubitril/valsartan improves LVEF and NT-proBNP levels in patients with heart failure on peritoneal dialysis
- Impact of Mitral Prosthesis-Patient Mismatch on Mortality and Outcomes After Valve Replacement
- Finerenone reduces mortality and heart failure risk (HR 0.644) in post-AMI patients
- Interval likelihood ratios improved correct management decision rates by 11.2 to 18.3 percentage points
- Combined endurance and resistance exercise improves peak oxygen consumption and quality of life in heart failure
- Higher prognostic nutritional index is associated with lower all-cause mortality risk in heart failure patients
- Delirium occurs in 18.5% of hospitalized heart failure patients, meta-analysis finds
- Immune-stromal imbalance drives heart failure after myocardial infarction, systematic review finds
- Engineered extracellular vesicles show potential for improving cardiac function and tissue repair in ischemic heart disease
- Evaluating the Efficacy of Oral Digoxin in Patients with Rheumatic Heart Disease
- Non-invasive telemedicine monitoring significantly improves self-care ability in patients with heart failure
- Finerenone reduces composite cardiovascular death and worsening heart failure events in patients with symptomatic heart failure
- Evaluating the Impact of Digital Health Interventions on Chronic Disease Self-Care Outcomes
- SGLT2 inhibitors associated with lower all-cause mortality in heart transplant recipients with type 2 diabetes
- Aprotinin and tranexamic acid show varying efficacy for hemostasis in neonatal cardiac surgery
- Research in coronary heart disease shows misalignment between investment and clinical guideline priorities
- SGLT2 inhibitors provide robust prognostic benefits in heart failure with inconsistent results in post-myocardial infarction settings
- High-intensity interval aerobic exercise improves brachial FMD in coronary artery disease and heart failure
- Conduction system pacing improves LVEF and reduces HF hospitalization vs biventricular pacing in heart failure
- Network meta-analysis reveals resistance training offers largest LVEF gains for adult heart failure patients compared to other exercise types
- Systematic review suggests modest risk reduction with SGLT2 inhibitors or ARNIs added to standard therapy in severe heart failure
- Natriuresis-guided diuretic protocols improve fluid removal and shorten hospital stays for acute decompensated heart failure patients compared to standard care approaches in this meta-analysis review
- Rate of drug concentration rise alters hemodynamic responses and mortality risk in coronary heart disease patients
- Polygenic scores link to atherosclerosis and ischemic heart disease in Russian populations
- TCM and probiotics may offer a promising direction for future precision prevention and management of coronary heart disease
- Two-lead CRT-D with atrial sensing shows noninferiority versus three-lead systems in heart failure patients
- Renal denervation combined with pulmonary vein isolation increases freedom from atrial fibrillation risk in resistant hypertension patients
- Structural cerebral abnormality prevalence rises from 23.1% prenatally to 50.3% postoperatively in isolated congenital heart disease
- Left Atrial Strain predicts major cardiovascular events with HR 0.91 in general population
- Lung ultrasound-guided decongestion reduces HF hospitalization and mortality risk in heart failure patients compared to standard care
- SGLT2 and dual SGLT1/2 inhibitors reduce cardiovascular death or heart failure hospitalization risk in type 2 diabetes patients
- Acute kidney function decline timing predicts mortality and heart failure outcomes in hospitalized patients
- Yiqi Fumai injection improved BNP reduction and heart function in acute heart failure patients compared to standard therapy alone
- LBBAP shows lower mortality and hospitalization versus biventricular pacing in CRT
- Lower VExUS grades predict reduced in-hospital mortality in acute heart failure patients
- Pre-transplant VAD support shows no survival benefit but increases stroke risk in pediatric heart transplant recipients
- Astragalus Granule plus Western medicine ranked best for overall clinical efficacy in heart failure
- Remote monitoring algorithms predict heart failure events, may reduce hospitalizations
- Serum resistin levels rise progressively with worsening severity of coronary heart disease and acute myocardial infarction in this meta-analysis
- Meta-analysis of exercise rehabilitation for HFpEF shows mixed outcomes on mortality and rehospitalization
- Breast arterial calcification linked to increased cardiovascular mortality risk
- Systematic review and meta-analysis of 3D cardiac simulations for congenital heart disease surgery
- Systematic review and meta-analysis links pediatric cerebral AVMs with congenital heart defects and outlines prognostic factors
- Pre-infection vaccination linked to lower cardiovascular and cerebrovascular event risks in SARS-CoV-2 infected individuals
- Systematic review finds CRT plus optimized medical therapy is highly cost-effective for symptomatic heart failure patients
- Routine prophylactic left atrial appendage closure did not significantly reduce the incidence of the primary composite endpoint
- Network meta-analysis of oral Chinese patent medicines for myocardial infarction with heart failure
- Simplified transitional care did not improve guideline adherence in acute heart failure patients over 6 months
- M-TEER reduces heart failure hospitalization risk across all health status levels in mitral regurgitation
- Meta-analysis suggests high BMI causally increases vascular-related dementia risk via blood pressure mediation
- Network meta-analysis of finerenone and SGLT2 inhibitors in heart failure with preserved or mildly reduced ejection fraction
- Narrative review explores strategic collaborations to expand interventional cardiology access in sub-Saharan Africa
- Meta-analysis links influenza vaccination to lower mortality in acute heart failure
- Meta-analysis shows SGLT2 inhibitors reduce all-cause mortality in heart failure patients
- Systematic review and meta-analysis finds no mortality benefit for alternative loop diuretics in chronic heart failure
- SGLT-2 inhibitors reduce heart failure hospitalization and stroke in patients with acute coronary syndrome
- Network meta-analysis compares glucose-lowering therapies for heart failure with reduced ejection fraction and type 2 diabetes
- Systematic review and meta-analysis reports 36.6% cognitive impairment prevalence in coronary heart disease patients
- Higher LDH levels linked to increased heart failure events in HFrEF patients
- Meta-analysis links elevated GDF-15 to mortality in acute heart failure
- CABG versus PCI in high-risk coronary revascularisation patients shows mixed outcomes over 5 years
- Transcatheter valve replacement improves outcomes in severe tricuspid regurgitation
- Systematic review and meta-analysis on face-directed fan therapy for dyspnea in advanced disease
- Qiliqiangxin reduces cardiovascular events in heart failure with reduced ejection fraction across LVEF subgroups
- Omecamtiv mecarbil shows trend toward reduced serious arrhythmia risk in HFrEF post hoc analysis
- Systematic review and meta-analysis of erythropoiesis-stimulating agents in chronic heart failure and anaemia
- Meta-analysis and cohort study suggest association between SGLT2 inhibitors and reduced arrhythmia recurrence
- Network meta-analysis suggests mind-body exercises improve quality of life and function in chronic heart failure patients
- Nurse and social worker telecare team intervention improved quality of life in high-risk patients with COPD, heart failure, or interstitial lung disease
- Structured Exercise Training Improves LVEF and LDL-C in HFmrEF Patients After PCI
- Vericiguat showed no significant effect on flow-mediated dilation in a small pilot trial of 26 heart failure patients
- Systematic review shows UNa-guided diuretic titration increases short-term diuresis in hospitalized acute decompensated heart failure patients
- Meta-analysis finds Cimlanod does not reduce mortality in HFrEF, increases hypotension risk
- Beta-blockers show no mortality benefit in MI patients with preserved ejection fraction
- Meta-analysis finds conduction system pacing reduces heart failure hospitalizations in HFmrEF
- Sex differences in genetic correlation between ischaemic heart disease and depression found in 1.14 million European ancestry individuals
- Network meta-analysis of oral Chinese patent medicines for coronary heart disease with diabetes
- Machine learning model using routine clinical indicators predicts coronary heart disease risk
- Deep learning model screens for transthyretin amyloid cardiomyopathy using ECG images
- Mendelian randomization links higher plasma EPA to increased ischemic heart disease odds
- NICE-Support programme improves frailty and quality of life in stable heart failure patients
- Systematic review and meta-analysis shows remote monitoring reduces mortality and hospitalizations in heart failure
- Narrative review examines multimorbidity impact on sepsis morbidity and mortality outcomes
- Chagas disease associated with higher in-hospital mortality in adults hospitalized with heart failure
- Systematic Review and Meta-Analysis Finds Palliative Care Improves Quality of Life in Advanced Heart Failure
- Non-randomized preprint on dapagliflozin and epicardial adipose tissue in HFpEF
- Cochrane review finds very low-certainty evidence on early versus late cardiac surgery start times in France
- Higher Lactate Dehydrogenase-to-Albumin Ratio Associated With Increased Readmissions and Mortality in Heart Failure
- Narrative review summarizes Systemic Immune-Inflammation Index thresholds and limitations in coronary heart disease management
- GenMetS polygenic score association with cardiometabolic risk in Asian populations
- Observational study reveals 'tug-of-war' contraction patterns in healthy and infarcted hearts
- Randomized trial of anakinra in heart failure shows increased IL-1Ra levels versus placebo over 24 weeks
- Higher systemic immune-inflammation index linked to increased mortality risk in hospitalized heart failure patients
- Circulating SVEP1 Protein Associated With Major Adverse Cardiovascular Events in Hemodialysis Patients
- Review Links Central Adiposity to Higher Infective Endocarditis Risk in UK Biobank
- Deep Learning Model Outperforms Guidelines for Heart Failure Prognosis
- Telemedicine applications in general practice show positive clinical outcomes for chronic diseases
- Jordan guideline review highlights SGLT2 inhibitor access barriers for heart failure patients
- Systematic review synthesizes Rhaponticum species chemistry, traditional uses, and research gaps across multiple conditions
- Multi-ancestry meta-analysis identifies X-chromosome loci for heart failure phenotypes
- Registry study links ARNI therapy groups to divergent mortality and hospitalization risks in HFrEF patients
- PSI-QPI metrics improved prediction of TTN-TV disease penetrance and expressivity in cardiomyopathy patients
- Hospital stay and mortality vary by pandemic wave and vaccination status in severe COVID-19
- Retrospective cohort study links congenital heart surgery with CPB to early postoperative cerebral desaturation events in infants
- Diabetes Prevalence and Clinical Correlates in Hospitalized Heart Failure Patients in China
- Discharge to healthcare facilities increased 6-month readmission risk in Chinese heart failure patients compared to home discharge
- Higher RAR linked to increased in-hospital mortality in infants with congenital heart disease
- CRRT after heart transplantation linked to preoperative hemoglobin and VIS score in cohort study
- Single-center review links CPAP compliance to better survival in LVAD patients with OSA
- TyG-NLR combined index associated with all-cause mortality in heart failure patients
- Systematic literature review examines machine learning applications in congenital heart disease across 432 references
- Review of ginsenoside CK shows potential antiplatelet, anti-inflammatory, and cardioprotective effects in cardiovascular disease models
- Individual participant data meta-analysis shows exercise-based cardiac rehabilitation reduces hospitalization, not mortality in coronary heart disease
- Technology-based Cardiac rehabilitation Therapy improves functional capacity and quality of life in women with cardiac disease
- Non-traditional lipid indices associate with coronary heart disease risk in MASLD and type 2 diabetes patients
- Review Examines IL-32 Role in Cardiovascular Diseases and Atherosclerosis
- Narrative review summarizes evidence on exercise benefits for cardiovascular disease and mortality risk reduction
- Narrative review synthesizes evidence on myocardial strain imaging for pediatric congenital heart disease management
- Narrative review covers cardiovascular conditions and cognitive decline without reported trial data
- Meta-analysis of 13 trials finds SGLT2 inhibitors reduce heart failure hospitalization in myocardial infarction
- Beta-blockers show no benefit in preserved LVEF post-MI, but may help mildly reduced LVEF
- Review proposes pragmatic framework for pediatric heart failure management addressing myocarditis and MIS-C
- Retrospective observational study of 122 heart failure patients at 2,800 meters altitude in Quito
- Observational Cohort Study Links Dynamic Cardiac Shape to Cardiometabolic Disease Risk in UK Biobank
- Modeling Study Estimates Polygenic Embryo Screening Risk Reductions in IVF Patients and Egg Donors
- Standard diuretic therapy within GDMT yielded comparable outcomes to pleural drainage in elderly acute heart failure with moderate pleural effusion
- Narrative review on ultra-processed foods and cardiovascular disease mechanisms
- Review of heart failure medications and microbiome insights for individualized treatment strategies
- Obesity-metabolic indices associated with heart failure in coronary artery disease patients