N/A
Completed N=538
Genetic Research in Schizophrenia Using DNA Markers and Clinical Phenotypes
Source: ClinicalTrials.gov NCT00108303 ↗Enrolled (actual)
538
Serious AEs
0.0%
Results posted
Jan 2016
Primary outcomePrimary: Genetic Linkage — 5.2 log (odds ratio) — p=<0.001
Summary
Schizophrenia has long been known to be an illness with significant evidence for a genetic predisposition. The purpose of this study is to determine the genetic abnormalities that cause childhood and adult onset schizophrenia.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Genetic Linkage |
5.2 | <0.001 sig |
| PRIMARY Heritability Coefficient |
0.5; 0.5; 0.1 | 0.001 sig |
| PRIMARY Log of the ODDS of Linkage |
5.2; 5.2; 1 | — |
Eligibility Criteria
Inclusion Criteria
- Individuals thought to have schizophrenia or schizoaffective disorder, be the parent of such an individual, or be in the matched control group of unrelated individuals not thought to have schizophrenia or schizoaffective disorder
Exclusion Criteria
- Unable to give informed consent;
- Psychotic disorder judged to be secondary to substance abuse, psychotic disorder that appears to be secondary to a known medical or neurological disorder, or severe mental retardation
Data sourced from ClinicalTrials.gov (NCT00108303). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.