N/A N=110 Treatment

Word-Retrieval Treatment for Aphasia: Semantic Feature Analysis

Aphasia · Language Disorders · Speech Disorders

Bottom Line

View on ClinicalTrials.gov: NCT00125242 ↗

Enrolled (actual)

110

Serious AEs

0.0%

Results posted

Dec 2014

Primary outcome: Primary: Word Retrieval Accuracy — 7.15 d-index (effect size)

Study Design & Population

Study type: Interventional
Phase: N/A
Interventions: Semantic Feature Analysis (SFA)Training (Behavioral)
Age: Adult, Older Adult · 21+ yrs
Sex: All
Sponsor: US Department of Veterans Affairs
Primary completion: Feb 2009

Outcome Measures

Outcome	Result	p-value
PRIMARY Word Retrieval Accuracy	7.15	—

Summary

The purpose of this investigation is to further develop and test a treatment for word-finding problems in aphasia. The treatment is designed to strengthen meaning associations within categories of words (e.g., animals, tools, fruits). The treatment is also designed to be used as a search strategy in instances of word-finding difficulty. The study was devised to evaluate the extent to which treatment increases the ability to recall trained, as well as untrained, words.

Eligibility Criteria

Inclusion Criteria

Diagnosis of Wernicke's, Broca's, or Conduction aphasia with significant word-retrieval deficits
At least 6 months post-onset of single, left-hemisphere stroke
Minimum of high-school education
Visual and auditory acuity sufficient for experimental tasks
Nonverbal intelligence within normal limits

Exclusion Criteria

Diagnosed mental illness other than depression
Neurological condition other than that which resulted in aphasia
History of alcohol or substance abuse
Non-native English speaker
Premorbid history of speech/language disorder

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00125242). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.