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Home › Conditions › aphasia

Aphasia

6 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for aphasia

33 trials tracked for aphasia.

33Trials tracked
0Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 2 6 Phase 1 1 Other / NA 26
  1. Phase 2 Effect of Verb Network Strengthening Treatment (VNeST) on Lexical Retrieval in Aphasia Completed
  2. Phase 2 Brain Stimulation and Aphasia Treatment Completed
  3. Phase 2 Treating Intention In Aphasia: Neuroplastic Substrates Completed
  4. Phase 2 Effect of Repetitive Transcranial Magnetic Stimulation on Language in Alzheimer's Disease Completed
  5. Phase 2 Speech Entrainment for Aphasia Recovery Completed
  6. Phase 2 Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Chronic Aphasia Completed
Show 27 more trials
  1. Phase 1 Transcranial Magnetic Stimulation to Improve Speech in Aphasia Completed
  2. N/A Exercise as an Adjuvant to Aphasia Therapy Completed
  3. N/A Exercise Effects on Word Learning Completed
  4. N/A Using Transcranial Direct Current Stimulation (tDCS) to Improve Post-Stroke Aphasia Completed
  5. N/A Transcranial Direct Stimulation (tDCS) and Behavioral Intervention in Aphasia Completed
  6. N/A Adapting Acceptance and Commitment Therapy for Stroke Survivors With Aphasia Completed
  7. N/A Brain Biomarkers of Response to Treatment for Apraxia of Speech Completed
  8. N/A Assessing an Animal-Assisted Treatment Program for Adults With Aphasia: The Persons With Aphasia Training Dogs Program Completed
  9. N/A CB3 Pilot (Communication Bridge: A Person-centered Internet-based Intervention for Individuals With Primary Progressive Aphasia) Completed
  10. N/A Investigating the Effects of Rhythm and Entrainment on Fluency in People With Aphasia Completed
  11. N/A Phonomotor Treatment of Word Retrieval Deficits in Individuals With Aphasia Completed
  12. N/A Treatment Intensity - Apraxia of Speech Completed
  13. N/A Stepped Care for Aphasia Completed
  14. N/A Treatments of Acquired Apraxia of Speech Completed
  15. N/A Improving Aphasia Using Electrical Brain Stimulation Completed
  16. N/A A Novel Treatment for Aphasia and Apraxia of Speech : Measurement of Outcomes Completed
  17. N/A Word-Retrieval Treatment for Aphasia: Semantic Feature Analysis Completed
  18. N/A Yes/No Questionnaire for Aphasic Patients (YNQ) Completed
  19. N/A Digital Interventions in Neurorehabilitation: iTALKbetter Completed
  20. N/A Post-Stroke Aphasia and Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment Study Completed
  21. N/A TMS in Aphasia Recovery Completed
  22. N/A Transcranial Direct Current Stimulation (tDCS) and Intensive Therapy in Aphasia Completed
  23. N/A Dosage and Predictors of Naming Treatment Response in Aphasia Completed
  24. N/A Effects of Transcranial Direct Current Stimulation (tDCS) on Language Completed
  25. N/A Prism Adaptation in Left Brain Stroke Completed
  26. N/A Combining tDCS and CILT in Non-fluent Aphasia Completed
  27. N/A Determining Learning Ability in People With Aphasia Completed

Showing the 33 most-cited and recently-updated of 33 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Scoping review of machine learning models for post-stroke aphasia diagnosis and outcome prediction
Neurology Sys. Review
Scoping review of machine learning models for post-stroke aphasia diagnosis and outcome prediction Machine Learning Helps Predict Stroke Speech Recovery
This scoping review examines 19 articles regarding machine learning models for post-stroke aphasia. The authors synthesize applications in d…
New computer tools can predict how well a stroke survivor will regain their speech by analyzing many different types of patient data.
Frontiers May 7, 2026
Anodal tDCS combined with therapy enhanced verb naming in chronic post-stroke aphasia
Neurology RCT
Anodal tDCS combined with therapy enhanced verb naming in chronic post-stroke aphasia Stimulation plus therapy improves word finding in chronic stroke aphasia
This double-blind, sham-controlled crossover study investigated anodal tDCS over the left inferior frontal gyrus combined with verb naming t…
A small study found that combining brain stimulation with speech therapy helped people with chronic stroke aphasia name verbs better, with b…
May 1, 2026
Network meta-analysis of speech therapy for poststroke aphasia finds no single superior approach
Neurology Meta-analysis
Network meta-analysis of speech therapy for poststroke aphasia finds no single superior approach Speech therapy improves quality of life after stroke, study finds
This network meta-analysis of randomized controlled trials in patients with poststroke aphasia synthesized evidence on speech therapy.
Speech therapy after stroke can improve quality of life, but no single approach was clearly better for language recovery in a large review.
Apr 22, 2026
Protocol outlines planned meta-analysis investigating non-invasive brain stimulation effects in post-stroke aphasia
Neurology Meta-analysis
Protocol outlines planned meta-analysis investigating non-invasive brain stimulation effects in post-stroke aphasia Brain Stimulation Rewires Speech Centers After Stroke, New Analysis Suggests
This publication is a protocol describing a planned meta-analysis focused on patients with post-stroke aphasia.
This research could finally explain exactly how non-invasive brain stimulation helps stroke patients regain their ability to speak.
Frontiers Apr 22, 2026
Observational study examines social-cognitive task performance in individuals with aphasia following stroke
Neurology
Observational study examines social-cognitive task performance in individuals with aphasia following stroke Why Some Stroke Survivors Struggle to Read Minds (Even Without Language Problems)
This observational primary study assessed social-cognitive task accuracy in 44 individuals with aphasia following stroke.
A stroke survivor’s ability to understand others’ thoughts isn’t just tied to their language skills—it’s also linked to the health of their …
medRxiv Apr 21, 2026
Acupuncture frequency affects aphasia outcomes post-stroke in randomized trial
Neurology RCT
Acupuncture frequency affects aphasia outcomes post-stroke in randomized trial Does acupuncture speed up speech recovery after stroke, and does the needle speed matter?
This randomized controlled trial in 105 patients with post-ischemic stroke aphasia compared low-frequency and high-frequency acupuncture at …
Slowly twirling acupuncture needles helped stroke patients recover speech and understanding better than fast needles or fake needles after s…
Apr 17, 2026

Questions about aphasia

Are there different types of non-invasive brain stimulation for treating aphasia?

Two main types of non-invasive brain stimulation (NIBS) are commonly used to treat aphasia: transcranial direct current stimulation (tDCS) and repetitive transcranial magnetic stimulation (rTMS).

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Does high-frequency acupuncture provide better results for post-stroke aphasia?

A randomized trial indicates that high-frequency twirling acupuncture may improve language functions and quality of life for patients with post-stroke aphasia.

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Is there one specific type of speech therapy that is best for aphasia?

No single speech therapy is best for all people with aphasia; research shows several approaches can help, and the best choice depends on the individual.

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Does combining tDCS with therapy improve verb naming in chronic aphasia?

Yes, combining tDCS with therapy significantly improves verb naming in chronic post-stroke aphasia, with benefits lasting at least one month.

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Can machine learning help predict the outcome of my aphasia after a stroke?

Yes, machine learning can help predict aphasia recovery after stroke, with models achieving around 80% accuracy using factors like aphasia severity, cognitive performance, and education.

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See all 5 questions about aphasia →