Phase 4 N=107 Randomized Quadruple-blind Treatment

Supported Employment and Skills Training in Conjunction With Pharmacotherapy in Schizophrenia Patients

Schizophrenia

Bottom Line

View on ClinicalTrials.gov: NCT00183625 ↗

Enrolled (actual)

107

Serious AEs

26.2%

Results posted

Jun 2015

Primary outcome: Primary: Total Weeks Worked — 51.53; 41.37 Weeks — p=0.66

Study Design & Population

Study type: Interventional
Phase: Phase 4
Interventions: Individual Placement and Support (Supported Employment) (Behavioral); Social Skills Training (Behavioral); Olanzapine (Drug); Risperidone (Drug)
Age: Adult · 18+ yrs
Sex: All
Sponsor: University of California, Los Angeles
Primary completion: Jun 2005

Outcome Measures

Outcome	Result	p-value
PRIMARY Total Weeks Worked	51.53; 41.37	0.66
SECONDARY Body Mass Index	29.21; 30.4	.0176 sig

Summary

This study will compare employment support with behavioral skills training to employment support alone in schizophrenia patients taking either risperidone or olanzapine to determine which is more effective in helping the patients maintain a job.

Eligibility Criteria

Inclusion Criteria

Diagnosis of schizophrenia
Candidate for maintenance schizophrenia treatment
Willing to initiate and continue risperidone or olanzapine therapy for the duration of the study

Exclusion Criteria

Any serious medical problems other than schizophrenia that would interfere with the study

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00183625). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.