N/A N=146

Swallowing Function Before and After Surgery for Thyroid Goiter

Hypothyroidism

Bottom Line

View on ClinicalTrials.gov: NCT00205348 ↗

Enrolled (actual)

146

Serious AEs

0.0%

Results posted

Feb 2018

Primary outcome: Primary: Swallowing Quality of Life — 84.6; 92.3; 81.2; 87.1 units on a scale — p=0.0007

Study Design & Population

Study type: Observational
Phase: N/A
Interventions: —
Age: Adult, Older Adult · 18+ yrs
Sex: All
Sponsor: University of Wisconsin, Madison
Primary completion: Jan 2009

Outcome Measures

Outcome	Result	p-value
PRIMARY Swallowing Quality of Life	84.6; 92.3; 81.2; 87.1; 87.0; 93.1	0.0007 sig

Summary

To date, there have been no comprehensive studies on swallowing function in patients undergoing surgery for multinodular goiter. We hypothesize that 1. Multinodular goiter has significant effect on swallowing function in symptomatic and asymptomatic patients, which can be demonstrated by a standardized questionnaire and a formal swallowing evaluation and 2. Surgery will improve swallowing function as measured post-operatively by these same parameters. Patients with multinodular goiter will be asked to fill out a validated survey (SWAL-QOL) on swallowing function in addition to undergoing a formal swallowing evaluation before and after surgery for multinodular goiter (subtotal thyroidectomy) and compared to patients undergoing total thyroidectomy for follicular cancer and less extensive thyroid surgery for other benign processes (lobectomy or lobectomy plus isthmusectomy).

Eligibility Criteria

Inclusion Criteria

thyroidectomy

Exclusion Criteria

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Data sourced from ClinicalTrials.gov (NCT00205348). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.