N/A
Completed N=146
Swallowing Function Before and After Surgery for Thyroid Goiter
Source: ClinicalTrials.gov NCT00205348 ↗Enrolled (actual)
146
Serious AEs
0.0%
Results posted
Feb 2018
Primary outcomePrimary: Swallowing Quality of Life — 84.6; 92.3; 81.2; 87.1 units on a scale — p=0.0007
Summary
To date, there have been no comprehensive studies on swallowing function in patients undergoing surgery for multinodular goiter. We hypothesize that 1. Multinodular goiter has significant effect on swallowing function in symptomatic and asymptomatic patients, which can be demonstrated by a standardized questionnaire and a formal swallowing evaluation and 2. Surgery will improve swallowing function as measured post-operatively by these same parameters. Patients with multinodular goiter will be asked to fill out a validated survey (SWAL-QOL) on swallowing function in addition to undergoing a formal swallowing evaluation before and after surgery for multinodular goiter (subtotal thyroidectomy) and compared to patients undergoing total thyroidectomy for follicular cancer and less extensive thyroid surgery for other benign processes (lobectomy or lobectomy plus isthmusectomy).
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Swallowing Quality of Life |
84.6; 92.3; 81.2; 87.1; 87.0; 93.1 | 0.0007 sig |
Eligibility Criteria
Inclusion Criteria
- thyroidectomy
Exclusion Criteria
- na
Data sourced from ClinicalTrials.gov (NCT00205348). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.