Phase 2
Completed N=16
Melatonin Supplements for Improving Sleep in Individuals With Hypertension
Source: ClinicalTrials.gov NCT00238108 ↗Enrolled (actual)
16
Serious AEs
0.0%
Results posted
Sep 2012
Primary outcomePrimary: Sleep Quality — 88.1; 80.5 % (% asleep during 8 hour opportunity)
Summary
This study will evaluate the effectiveness of treatment with melatonin supplements in improving sleep in individuals with high blood pressure who are taking beta-blockers.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Sleep Quality |
88.1; 80.5 | — |
| SECONDARY Change in Systolic Blood Pressure |
-0.2; -0.4 | — |
Eligibility Criteria
Inclusion Criteria
- Diagnosed with uncomplicated hypertension
- Currently being treated with Atenolol (a beta-blocker)
Exclusion Criteria
- History of medical illness other than essential hypertension
- Personal or family history of psychiatric illness
- Current use of any medication other than anti-hypertensive drugs
- Any recent travel across time zones
- History of working various shifts on an irregular basis
Data sourced from ClinicalTrials.gov (NCT00238108). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.