Phase 1
N=101
Cardiac Home Education and Support Trial (CHEST): A Pilot Study
Coronary Artery Disease
Bottom Line
View on ClinicalTrials.gov: NCT00275340 ↗Enrolled (actual)
101
Serious AEs
—
Results posted
Jun 2009
Primary outcome: Primary: Health-related Quality of Life (SF-36v2-acute Form) — 72.6; 77.0; 60.4; 65.5 units on a scale — p=p<0.20
Study Design & Population
- Study type
- Interventional
- Phase
- Phase 1
- Interventions
- Peer Support (Other)
- Age
- Pediatric, Adult, Older Adult
- Sex
- All
- Sponsor
- University of Toronto
- Primary completion
- Apr 2007
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Health-related Quality of Life (SF-36v2-acute Form) |
72.6; 77.0; 60.4; 65.5; 72.2; 78.8 | p<0.20 |
| SECONDARY Pain (McGill Pain Questionnaire-Short Form) |
— | — |
| SECONDARY Interference With Activities (Brief Pain Inventory-Interference Subscale) |
— | — |
| SECONDARY Function (Human Activity Profile) |
— | — |
| SECONDARY Depressive Symptoms (Center for Epidemiologic Studies Depression Scale) |
— | — |
Summary
Coronary artery bypass graft (CABG) surgery is performed more frequently on individuals who are older and sicker than in previous years. Increased patient acuity and reduced hospital length of stays leave individuals ill prepared for their recovery following discharge. Individuals experience pain, functional impairment and depressive symptoms following discharge, which persist for 8 weeks in 50% of individuals. Unrelieved pain, functional decline and depressive symptoms predispose individuals to adverse events, impaired health-related quality of life (HRQOL), and increased morbidity and mortality.
Existing supports; including printed education materials, community care resources, cardiac rehabilitation programs and nurse-initiated telephone follow-up, fail to address concerns of individuals in this early period following hospital discharge.
Despite the positive health outcomes in other patient populations, valid studies examining the impact of telephone-based peer support to men and women after hospital discharge from CABG surgery were not found. It is anticipated that a home-based peer support program, delivered by telephone, will improve recovery and enhance HRQOL for individuals in the early weeks post hospital discharge from CABG surgery.
Eligibility Criteria
Inclusion Criteria (patients): Men and women who
- are having first-time non-emergency CABG surgery
- are judged ready for discharge
- are being discharged to home [either their own or to family/friends]
- have access to and are able to communicate over a telephone
- are able to read, write and understand English
Inclusion Criteria (peers): Men and women who
- have undergone CABG surgery within the last 5 years
- have access to and are able to communicate clearly over a telephone
- are able to read, write and understand English
- have attended a formal cardiac rehabilitation program
- are not associated with the current in-hospital peer volunteer program
Data sourced from ClinicalTrials.gov (NCT00275340). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.