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Patient Mode — summaries use plain language, avoiding clinical jargon.
Cardiology
RCT
Structured Exercise Training Improves LVEF and LDL-C in HFmrEF Patients After PCI
Heart function improved more with exercise than medicine alone in stable heart disease patients
This single-center randomized trial of 120 stable CAD patients with HFmrEF (LVEF 40-49%) post-PCI found that adding a 52-week structured exe…
A 52-week program of structured exercise plus standard heart medicines helped heart function recover better than medicines alone in patients…
May 1, 2026
Cardiology
RCT
Sirolimus-eluting iron bioresorbable scaffold shows higher late lumen loss than everolimus-eluting stents in coronary artery disease patients.
New iron scaffold matches metal stents for heart artery repair
This randomized trial enrolled 518 patients with myocardial ischemia and 1 or 2 de novo target lesions at 36 centers in China. The sirolimus…
A new iron heart scaffold matches metal stents in safety and effectiveness while dissolving over time.
Apr 29, 2026
Cardiology
Cohort
Off-pump CABG showed similar wound complications but fewer transfusions and shorter stays versus on-pump CABG in 394 patients.
Off-Pump Surgery Does Not Reduce Leg Wound Risks In Heart Patients
This single-center retrospective cohort study evaluated 394 patients undergoing isolated coronary artery bypass grafting. After propensity s…
New data shows that avoiding the heart-lung machine does not protect leg incisions from infection or poor healing in heart bypass patients.
Frontiers
Apr 29, 2026
Cardiology
Cohort
Poor R-wave progression and all-cause mortality in adults without coronary artery disease
Heart rhythm pattern shows borderline link to death risk
This cohort study of 6,323 adults from the Multi-Ethnic Study of Atherosclerosis examined the association between poor R-wave progression an…
A long-term look at heart electrical patterns suggests a possible, though uncertain, link to higher mortality in some adults.
medRxiv
Apr 28, 2026
Cardiology
Cohort
Epicardial adipose tissue volume normalized to heart volume associated with obstructive coronary artery disease
Heart fat levels may link to coronary artery disease
This cohort study of 27,500 CT scans evaluated epicardial adipose tissue volume (EATV) in a general population and a clinical cohort with su…
Higher levels of fat surrounding the heart are linked to an increased risk of obstructive coronary artery disease.
medRxiv
Apr 27, 2026
Cardiology
RCT
Post-PCI Angiographic Microcirculatory Resistance and 3-Year Cardiac Events in FAVOR III China
High blood vessel resistance after heart procedure linked to higher heart attack risk
This post hoc analysis of the FAVOR III China trial evaluated Angiographic Microcirculatory Resistance (AMR) in 3,404 patients undergoing pe…
A look at data from a major heart trial shows that if blood flow resistance stays high after a stent, patients face a greater risk of seriou…
Apr 24, 2026
Genetics & Precision Medicine
Cohort
Polygenic risk score enrichment reduces sample size needs for coronary artery disease and inflammatory bowel disease trials.
Smarter trial designs could cut study sizes by 60% for heart disease
This in silico observational cohort study used UK Biobank data to model trial designs enriched for polygenic risk. Enriching to the upper 25…
Using genetic risk scores to pick high-risk volunteers could shrink trial sizes by 60% for heart disease and 78% for IBD, speeding up resear…
medRxiv
Apr 23, 2026
Diabetes & Endocrinology
Cohort
Inflammatory indices associated with increased chronic kidney disease risk in coronary artery disease cohort.
A Simple Blood Test Could Predict Kidney Disease Risk in Heart Patients
This cohort study of 5181 patients with coronary artery disease examined inflammatory markers. All four indices showed significant associati…
A common blood test could warn heart patients about their kidney risk years before damage starts.
Frontiers
Apr 23, 2026
Rheumatology
Cohort
Lipoprotein(a) concentrations associate with coronary artery disease severity in single-center observational cohort of 238 adults.
Higher Lipoprotein(a) Linked to Worse Heart Disease Severity
This single-center observational cohort study assessed Lipoprotein(a) concentrations in 238 adults referred for elective coronary angiograph…
Higher levels of lipoprotein(a) were found in patients with more severe coronary artery disease blockages in Kazakhstan.
Frontiers
Apr 23, 2026
Diabetes & Endocrinology
Cohort
Admission HbA1c and In-Stent Restenosis in CAD Patients After PCI
One blood sugar measure linked to repeat heart procedures
This retrospective observational cohort study assessed admission glycated hemoglobin (HbA1c) levels and in-stent restenosis (ISR) in 6,297 C…
In nearly 6,300 heart patients who had a stent, one blood sugar measure was tied to a higher chance of needing another procedure to clear th…
Frontiers
Apr 23, 2026
Cardiology
RCT
Remote i-CARE intervention improves self-care behaviors in coronary artery disease patients
Your Phone Can Help You Manage Heart Disease
In this randomized controlled trial of 294 community-dwelling adults with CAD, the remotely delivered i-CARE intervention led to significant…
Imagine waking up with a heart condition that requires daily attention.
Apr 22, 2026
Drug Pipeline
Cohort
Review of ginsenoside CK shows potential antiplatelet, anti-inflammatory, and cardioprotective effects in cardiovascular disease models.
This Natural Compound Could Shield Hearts and Prevent Strokes
This review evaluated ginsenoside CK and protopanaxadiol type ginsenosides regarding cardiovascular conditions. The analysis demonstrated an…
A specific compound from ginseng shows strong promise for protecting against heart disease and stroke.
Frontiers
Apr 22, 2026