N/A
Completed N=37
Impact of Using Mini-Bronchoalveolar Lavage as a Diagnostic Test for Ventilator-Associated Pneumonia
Source: ClinicalTrials.gov NCT00319644 ↗Enrolled (actual)
37
Serious AEs
0.0%
Results posted
Nov 2012
Primary outcomePrimary: Change in Antibiotic Usage or Exposure — 11.87; 7.76 days — p=0.26
Summary
The proposed study will evaluate adult patients admitted to the medical or surgical intensive care units (ICUs) at San Francisco General Hospital (SFGH). On admission, patients will be randomized in a 1:1 manner to the mini-bronchoalveolar lavage (BAL) quantitative culture arm in the setting of suspected ventilator-associated pneumonia (VAP) versus the tracheal aspirate culture arm, which is the current test available at SFGH.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Change in Antibiotic Usage or Exposure |
11.87; 7.76 | 0.26 |
| PRIMARY Antibiotics Exposure Days |
4; 5.81 | — |
Eligibility Criteria
Inclusion Criteria
- All adult patients (> age 18) admitted to 5E, 5R, and 4E intensive care units and are on the ventilator for greater than 48 hours and expected to remain on the ventilator for awhile
- Study procedures would be performed only in patients clinically suspected of having VAP.
Exclusion Criteria
- Severe respiratory distress at the time of suspected VAP defined by:
- FiO2 ≥ 0.7
- PEEP ≥ 12
Data sourced from ClinicalTrials.gov (NCT00319644). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.