Phase 4
Completed N=674
Bio-Behavioral Predictors of the Efficacy of Nicotine Replacement Therapy (NRT)
Source: ClinicalTrials.gov NCT00326781 ↗Enrolled (actual)
674
Serious AEs
0.0%
Results posted
Mar 2010
Primary outcomePrimary: Continuous Abstinence at End of Treatment (Self-report)(Defined as the Number of Consecutive Days Without Smoking a Cigarette for Each Subject) — 83; 75 Participants
Summary
The purpose of this research study is to:
1. compare the effectiveness of a nicotine patch and nicotine nasal spray for smoking cessation; and
2. identify predictors of response to these alternate forms of nicotine replacement therapy (NRT).
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Continuous Abstinence at End of Treatment (Self-report)(Defined as the Number of Consecutive Days Without Smoking a Cigarette for Each Subject) |
83; 75 | — |
| SECONDARY Verified 7-day Point Prevalence Abstinence at End Of Treatment. |
112; 95 | — |
Eligibility Criteria
Inclusion Criteria
- The subjects will be male and female smokers age 18-75.
- Eligible smokers will be those currently smoking at least 10 cigarettes a day.
Exclusion Criteria
- Planning a pregnancy, pregnant, or lactating
- Current addiction to opiates, cocaine, or stimulants
- Skin allergies or chronic dermatitis (based on medical history/self-report)
- An Axis 1 major psychiatric disorder
Data sourced from ClinicalTrials.gov (NCT00326781). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.