N/A
N=129
Treatment for Veterans With Military Sexual Trauma
Stress Disorders, Post-Traumatic · Depressive Symptoms · Anxiety Symptoms · Quality of Life
Bottom Line
View on ClinicalTrials.gov: NCT00371644 ↗Enrolled (actual)
129
Serious AEs
10.1%
Results posted
Dec 2014
Primary outcome: Primary: PTSD Checklist (PCL) — 65.53; 65.40; 51.39; 57.89 units on a scale
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Cognitive Processing Therapy (Behavioral); Present-Centered Therapy (Behavioral)
- Age
- Adult, Older Adult · 18+ yrs
- Sex
- All
- Sponsor
- US Department of Veterans Affairs
- Primary completion
- Jun 2010
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY PTSD Checklist (PCL) |
65.53; 65.40; 51.39; 57.89; 52.71; 59.35 | — |
Summary
The purpose of this study is to evaluate the effectiveness of Cognitive Processing Therapy (CPT) versus Present-Centered Therapy (PCT) in treating current post-traumatic stress symptoms associated with sexual assault that occurred while veterans were serving in the military.
Eligibility Criteria
Inclusion Criteria
- Veteran (female or male) from any era with a current diagnosis of PTSD due to MST
- Experienced MST no less than 3 months prior to entering the trial
- Identify that MST is the trauma that is causing the worst current distress (if other traumas also experienced)
- Have at least one clear memory of the trauma (sufficient to write impact statement)
- Consent to be randomized into treatment
- Not receive other psychotherapy during the 6 weeks of active treatment
- (if on psychoactive medications) if new antidepressant, be on stable medication regimen for a minimum of 6 weeks prior to entering the trial (if recent changes to antidepressant dosage or additions or changes of antipsychotic or anti-anxiety medication, eligible immediately)
Exclusion Criteria
- Current substance dependence
- Prior substance dependence that has not been in remission for at least 3 months
- Any current psychotic symptoms
- Current mania or unstable Bipolar Disorder
- Prominent current suicidal or homicidal features
- Any severe cognitive impairment or history of Organic Mental Disorder
- Current involvement in a violent relationship
Data sourced from ClinicalTrials.gov (NCT00371644). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.