N/A N=91 Cortisol Suppression and Startle Responses in Posttraumatic Stress Disorder (PTSD)
Post Traumatic Stress Disorder
Primary: Mean Baseline Startle Magnitude During Fear Conditioning — 48.401; 56.595; 115.778; 57.684 microvolts
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=41 Vortioxetine for Posttraumatic Stress Disorder
Post-Traumatic Stress Disorder
Primary: Change Clinician Administered PTSD Scale Score — 16; 17 score on a scale
N/A N=88 Post-traumatic Stress Disorder (PTSD) Symptoms in Later Life
Post Traumatic Stress Disorder
Primary: The Trauma History Questionnaire (THQ; Green, 1996) — 5.93; 0.76; 3.81; 0.97 score on a scale
N/A N=139 Prevention of Post-traumatic Stress Disorder by Telephone Based Cognitive Behavioral Therapy
Stress Disorder - Post-traumatic (Acute)
Primary: Severity of PTSD Symptoms — 43.4; 43.9 CAPS total Score at treatment end — p=0.927
Phase 3 N=80 Post Traumatic Stress Disorder (PTSD) Hyperarousal Symptoms Treated With Physiological Stress Management
Stress Disorders, Post-Traumatic
Primary: Change Scores for Criteria D Items on the CAPS Structured Clinical Interview — -1.20; -6.27 units on a scale — p=.27
N/A N=124 Cognitive Behavioral Treatments for Post-traumatic Stress Disorder (PTSD) Sleep Disturbance
Post-traumatic Stress Disorder
Primary: Weekly Number of Nightmares — 3.95; 3.88; 3.28; 3.47 weekly nightmares
N/A N=134 PTSD (PostTraumatic Stress Disorder) Services for Veterans With SMI (Severe Mental Illness)
Post Traumatic Stress Disorder · Schizophrenia · Schizoaffective Disorder
Primary: Posttraumatic Stress Disorder (PTSD) Checklist (PCL) — 66.94; 66.33; 51.20; 60.60 score on a scale
N/A N=169 Brief Treatment for Posttraumatic Stress Disorder
PTSD
Primary: Clinician Administered PTSD Scale, 5 (CAPS-5) — 31.55; 25.12; 29.59; 25.41 score on a scale
N/A N=60 Implementing a Skills Training Evidence-Based Treatment for Posttraumatic Stress Disorder in Primary Care
Posttraumatic Stress Disorder
Primary: Posttraumatic Stress Disorder Symptoms Measured by PTSD Checklist for DSM-5 (PCL-5) — 61.48; 58.28; 39.12; 36.30 score on a scale
Phase 4 N=37 Combination Treatment for Posttraumatic Stress Disorder (PTSD) After the World Trade Center (WTC) Attack
Posttraumatic Stress Disorder
Primary: Clinician Administered PTSD Scale (CAPS) — 72.6; 65.4; 40.7; 49.0 units on a scale — p=.01
N/A N=112 The Effect of Reducing Posttraumatic Stress Disorder Symptoms on Cardiovascular Risk
PTSD
Primary: Change From Baseline to Post-Intervention in 24-hour Heart Rate Variability (HRV) Estimated From the Standard Deviation of the Interbeat Interval of Normal Sinus Beats…
Phase 3 N=200 Comparison of Two Treatments for Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
Primary: PTSD Symptoms — 10.02; 10.87; 15.12; 10.78 units on a scale
N/A N=25 DoD PTSD November 13 - Information Processing Modification in the Treatment of PTSD
Stress Disorders, Post-Traumatic
Primary: Post-Traumatic Stress Disorder Checklist-Military Version (PCL-M) — 63.08; 61.71; 42.83; 51.65 units on a scale
N/A N=110 Effectiveness of Three Different Psychotherapies for Chronic Post-Traumatic Stress Disorder
Post-Traumatic Stress Disorder
Primary: Clinician-Administered PTSD Scale (CAPS) — 68.9; 72.1; 68.9; 39.8 units on a scale
N/A N=83 Family Involvement in Treatment for PTSD
Posttraumatic Stress Disorder
Primary: Qualitative Interviews - Perspectives on Family Involvement in PTSD Treatment — 33; 20; 27; 16 participants — p=<0.05
N/A N=28 Resolving Psychological Stress
Post-Traumatic Stress Disorder · Alcohol Use Disorder
Primary: PTSD Symptoms Using PTSD Checklist-5 (PCL-5) at Baseline and 15 Days — 33.2; 36.6; 31.2; 28.2 units on a scale — p=0.322
N/A N=81 Cognitive Training for PTSD
Posttraumatic Stress Disorder
Primary: Clinician Administered PTSD Scale - Reexperiencing — 2.6; 2.96 score on a scale
N/A N=85 Breathing Meditation Intervention for Post Traumatic Stress Disorder
Stress Disorders, Post-Traumatic
Primary: Change in PTSD Checklist (PCL) — -5.6; -6.8; -4.8; -6.8 score on a scale
N/A N=110 Cognition and Psychotherapy in PTSD
Posttraumatic Stress Disorder (PTSD)
Primary: Change in PTSD Checklist (PCL-5) — 9.25; 11.94; 15.91 change in units on a scale
Phase 4 N=700 Sequenced Treatment Effectiveness for Posttraumatic Stress
PTSD
Primary: PTSD Symptoms — 39.3; 38.6; 40.5 units on a scale
Phase 3 N=36 Exposure Therapy for Chronic PTSD: Efficacy and Mechanisms
Combat Disorders · Posttraumatic Stress Disorder
Primary: Clinician Administered PTSD Scale (Pre & Posttreatment) — 30.0; 53.6 units on a scale
Phase 4 N=65 Brain Markers of Treatment Response in Post-Traumatic Stress Disorder (PTSD)
Post-traumatic Stress Disorder
Primary: Percent Change in Brain Response Measured by Functional Magnetic Resonance Imaging (fMRI) — -.92; .07 percent change in BOLD signal — p=.001
Phase 4 N=40 Tramadol Extended-Release (ER) for Posttraumatic Stress Disorder (PTSD)
Post-Traumatic Stress Disorder
Primary: Clinician-Administered PTSD Scale (CAPS) — 79.1; 81.9; 90.0; 91.0 units on a scale — p=0.286
N/A N=45 Treating People With Post-Traumatic Stress Disorder With Cognitive Behavioral Therapy for Insomnia
Post-Traumatic Stress Disorder
Primary: Sleep Latency (SL) — 14.27; 44.31 minutes
N/A N=120 Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial
Post-traumatic Stress Disorder · Alcohol Abuse · Alcohol Dependence
Primary: Number of Patients With High Levels of Adolescent PTSD Symptoms — 9; 12; 11; 12 Participants — p=0.71
Phase 2 N=129 Orvepitant (GW823296) in Adult Post Traumatic Stress Disorder
Post-Traumatic Stress Disorder
Primary: Change From Baseline in the 17-item Clinician Administered Posttraumatic Stress Disorder (PTSD) Scale (CAPS) Total Severity Score at Week 12 — -25.75; -31.38 Score on…
Phase 2 N=212 A Phase 2b Study of BNC210 Tablet Formulation in Adults With Post-Traumatic Stress Disorder (PTSD)
Post-Traumatic Stress Disorder
Primary: Change From Baseline on the Clinician Administered Post-Traumatic Stress Disorder (PTSD) Scale for the Diagnostic and Statistical Manual of Mental Disorders, Fifth…
N/A N=31 Information Processing Modification in PTSD (Oct. 18)
Stress Disorders, Post-traumatic
Primary: Post-Traumatic Stress Disorder Checklist-Military Version (PCL-M) — 57.14; 61.33; 52.21; 53.78 units on a scale
Phase 2 N=17 Prolonged Exposure and Oxytocin
PTSD
Primary: PTSD Symptom Severity — 13.00; 17.71 scores on a scale
N/A N=69 Efficacy and Neural Mediators of Response to Trauma Management Therapy for PTSD
PTSD
Primary: Change in Clinician-Administered PTSD Scale for DSM-5 — 38.39; 35.67; 27.15; 29.31 score on a scale — p=0.4154