Phase 1
Completed N=192
Automatic External Defibrillation Monitoring in Cardiac Arrest
Death, Sudden, Cardiac · ventricular fibrillation · Tachycardia, Ventricular
Source: ClinicalTrials.gov NCT00382928 ↗
Enrolled (actual)
192
Serious AEs
0.0%
Results posted
Jul 2014
Primary outcomePrimary: Number of Participants Without Defibrillation — 94; 97 participants
Summary
We propose to randomize automatic external cardioverter/defibrillators (AECD) in patients who are at high risk for life-threatening abnormal heart rhythms (arrhythmias) and are admitted to the telemetry ward, all other treatments being constant including cardiopulmonary resuscitation.
We hypothesize that the automatic, rapid, accurate and specific diagnostic and therapeutic technology used in AECDs will further increase the rate of survival in patients with cardiac arrest through rapid and automatic defibrillation, independent of operator initiation, as compared to standard cardiopulmonary resuscitation initiated by healthcare providers.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Number of Participants Without Defibrillation |
94; 97 | — |
| SECONDARY Frequency of Abnormal Rhythms Monitored by the AECD |
9; 1; 10; 5 | — |
| SECONDARY Survival to Discharge |
95; 97 | — |
| SECONDARY Cerebral Performance at Discharge |
1 | — |
Eligibility Criteria
Inclusion Criteria
- All patients admitted to telemetry ward and emergency department
- Age > 18 years.
Exclusion Criteria
- Pregnant women
- Patients with R wave less than 0.5 millivolts.
- Patients with functioning Internal Cardiac Device.
- Patients with cardiac pacemakers if oversensing by AECD is demonstrated (double counting of pacer spikes).
- Patients with visible chest lesions that would prevent AECD pad placement.
- Patients who are designated Do Not Resuscitate.
- Right bundle branch block.
- Patients with Parkinson's disease.
- Patients with seizure disorders
Data sourced from ClinicalTrials.gov (NCT00382928). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.