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N/A N=9,454 Randomized Prevention

Scientific Evaluation of Peer Education and STD Treatment to Reduce the Spread of HIV in Zimbabwe

HIV Infections

Enrolled (actual)
9,454
Serious AEs
0.0%
Results posted
Aug 2019
Primary outcome: Primary: HIV Incidence at the Community Level — 1.49; 2.04 HIV infections per 100 person-years

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
Peer education among commercial sex workers and clients (Behavioral); Condom distribution and promotion (Behavioral); Syndromic treatment of sexually transmitted infections (Procedure); Systemic counselling for STI patients (Procedure)
Age
Pediatric, Adult · 15+ yrs
Sex
All
Sponsor
Imperial College London
Primary completion
Feb 2003

Outcome Measures

OutcomeResultp-value
PRIMARY
HIV Incidence at the Community Level
1.49; 2.04
SECONDARY
Self-reported Genital Ulcers
9.04; 7.47 <0.05 sig
SECONDARY
Self-reported Urethral or Genital Discharge
11.91; 10.50 <0.05 sig
SECONDARY
Percentage of Participants Reporting Cessation of Sexually Transmitted Infection Symptoms
71.58; 60.44 <0.05 sig
SECONDARY
Percentage of Participants Reporting More Than One Casual Partner in the Past 3 Years
14.59; 13.38 <0.05 sig
SECONDARY
Percentage of Participants Attending a Peer Education or Other Programme Meeting
20.25; 4.75 <0.05 sig
SECONDARY
Percentage of Participants Scoring 60% or Above on an Index of HIV/AIDS Knowledge
51.40; 47.30 <0.05 sig

Summary

The purpose of this study is to determine whether community-based peer education and condom distribution combined with improved treatment of sexually transmitted infections are effective in reducing the spread of HIV infection in a sub-Saharan African population

Eligibility Criteria

Inclusion criteria

Age: Males aged 17-54 years; females aged 15-44 years at last birthday Residence: Slept in a household in the study areas on at least 4 nights in the last 30 days

Exclusion criteria

Age: Males below the age of 17 years at last birthday or aged 55 years or above; females below the age of 15 years at last birthday or aged 45 years or above Residence: Did not sleep in a household in the study areas on at least 4 nights in the last 30 days

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00390949). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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