Multicomponent psychosocial interventions improve antiretroviral therapy adherence in people with HIV
Multicomponent support boosts HIV medicine taking for people living with the virus
This systematic review and network meta-analysis evaluated psychosocial interventions for people with HIV. The analysis included 7,808 parti…
A large review found that multicomponent psychosocial interventions significantly improved antiretroviral therapy adherence in people with H…
Target trial emulation in Johannesburg shows dolutegravir associated with greater weight and blood pressure increases versus efavirenz
New HIV drug linked to higher weight and blood pressure in South Africa
This target trial emulation compared dolutegravir to efavirenz in 2930 treatment-naive individuals in Johannesburg, South Africa. Over 24.0 …
People starting a new HIV drug in South Africa gained more weight and saw higher blood pressure than those on an older treatment.
Systematic review and meta-analysis finds subtyping methods linked to HIV recombinant form prevalence
New HIV variants hide in plain sight due to testing limits
This systematic review and meta-analysis of over 400 peer-reviewed studies examines HIV subtype prevalence and subtyping methodologies. The …
Scientists found that how we test for HIV changes what we think we know about new virus forms.
Mini-review discusses post-discharge care transitions for people living with HIV
Hospital discharge transitions impact outcomes for people with HIV
This mini-review examines post-discharge care transitions for hospitalized people living with HIV, particularly in low-income settings. The …
Recent data shows that nearly one in five people with HIV are readmitted to the hospital after being discharged in low-income settings.
CHIP mutations linked to higher lymph node metabolic activity in people with treated HIV
CHIP Mutations Linked to Lymph Nodes Not Arteries in HIV Patients
This cohort study of 230 people with HIV ages 31-74 years found that clonal hematopoiesis of indeterminate potential (CHIP) was not associat…
New research shows HIV patients with specific gene changes have active lymph nodes but not thicker arteries yet.
Narrative review examines multimorbidity impact on sepsis morbidity and mortality outcomes
Sepsis Risk Skyrockets When You Have Multiple Chronic Conditions
This narrative review synthesizes evidence regarding sepsis in patients with multimorbidity including type 2 diabetes and heart failure. Aut…
Common chronic diseases like diabetes and heart failure create hidden traps that make sepsis much harder to fight and treat.
Mathematical modelling review projects TB incidence and mortality declines in South Africa adults by 2030
New TB Test Could Cut Cases in Half
This mathematical modelling review analyzes Tuberculosis and HIV dynamics in South African adults using 1000 parameter combinations. It proj…
A simple swab test could stop TB from spreading by finding cases faster, especially in places where people struggle to get diagnosed.
Systematic review and meta-analysis finds higher TB prevalence among people living with HIV in Africa
TB’s Hidden Link: Why HIV Changes the Risk Picture
This systematic review and meta-analysis evaluated bacteriologically-confirmed tuberculosis prevalence in 264,530 people across Southern and…
If you have HIV, your risk of missing a deadly TB diagnosis is far higher—and this study explains why that gap must close now.
Systematic review shows rapid diagnostic tests offer faster, cheaper HIV detection for LAI-PrEP users with low certainty evidence.
Rapid tests find HIV just as well as lab tests but cost less and work faster.
This systematic review and meta-analysis evaluated HIV detection strategies, including rapid diagnostic tests (RDTs), laboratory-based immun…
For people on long-acting HIV prevention, rapid tests match lab accuracy while cutting costs and speeding up treatment starts.
Perspective Review Evaluates Informed Free Choice Model for HIV Care in U.S. and Global Settings
New HIV Guidelines Open Door to Breastfeeding—But Safety Demands More Than Just a Prescription
This perspective review examines the Informed Free Choice model compared to conventional shared decision-making for people living with HIV. …
This new framework gives parents with HIV the tools and support to feed their babies safely, while fighting the stigma and unfair rules that…
Imiquimod TLR7 stimulation shows sex-specific immune responses in HIV and non-HIV populations
Research shows immune reactions to imiquimod vary between men and women with HIV
This cohort study evaluated TLR7 stimulation with imiquimod in 1,326 individuals living with HIV and 43 people without HIV. Women living wit…
Women with HIV show different immune reactions to imiquimod than men, suggesting doctors may need to consider biological sex when developing…
Switching from EFV/TDF/3TC to B/F/TAF or DTG/3TC in virologically suppressed PLWH shows no significant between-group metabolic differences over 24 months.
Switching HIV drugs showed similar metabolic changes over two years in this real-world study.
This retrospective real-world study evaluated 326 virologically suppressed persons with HIV (PLWH) switching from efavirenz/tenofovir disopr…
Switching HIV drugs caused similar weight gain and metabolic shifts over two years, meaning lifestyle factors matter more than the specific …