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N/A N=38 Randomized Single-blind Treatment

Wedged Orthoses and Knee Osteoarthritis

Knee Osteoarthritis

Enrolled (actual)
38
Serious AEs
0.0%
Results posted
Jun 2017
Primary outcome: Primary: Knee Adduction Moment at Baseline — 0.376; 0.342 Nm/(kg-m)

Study Design & Population

Study type
Interventional
Phase
N/A
Interventions
wedged inshoe orthosis (Device); neutral inshoe orthosis (Device)
Age
Adult, Older Adult · 40+ yrs
Sex
All
Sponsor
University of Delaware
Primary completion
Feb 2006

Outcome Measures

OutcomeResultp-value
PRIMARY
Knee Adduction Moment at Baseline
0.376; 0.342
PRIMARY
Knee Adduction Moment After 12 Months
0.408; 0.358

Summary

The five-year goal of this project is to investigate the effect of in-shoe wedged orthoses on lower extremity function in patients with knee osteoarthritis. In general, our aims address the long-term effects of orthoses. The investigators hypothesize that subjects who use the lateral wedged in shoe orthosis will result in altered gait mechanics that reflect a reduction in the frontal plane knee joint moment compared to subjects who use a neutral in shoe orthosis.

Eligibility Criteria

Inclusion Criteria

  • Diagnosed unilateral knee osteoarthritis by a qualified physician
  • Recent (within 3 months of entrance into the study) radiographic confirmation of OA grade (I-IV) as evidenced by joint space narrowing and the presence of osteophytes
  • A score of 50-90 mm on a 100 mm visual analogue pain scale for walking
  • Ability to walk independently without the use of assistive devices

Exclusion Criteria

  • History of lower extremity joint surgery or other lower extremity injury that would hinder ambulation
  • Severe foot deformity that would prevent the accommodation of the wedged orthotic device
  • Other disease process such as neurologic, cardiac, or oncologic, that would hinder one's ability to ambulate
  • Any condition, such as diabetes, that results in loss of sensation in the lower extremities
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00420147). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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