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Phase 3 N=750 Randomized Treatment

Disease Management for Smoking Cessation

Smoking Cessation

Enrolled (actual)
750
Serious AEs
2.5%
Results posted
Jun 2017
Primary outcome: Primary: 7-day Point Prevalence Abstinence From Cigarettes — 68; 56; 56 Participants — p=0.54

Study Design & Population

Study type
Interventional
Phase
Phase 3
Interventions
High intensity disease management (Behavioral); Low intensity disease management (Behavioral); Comparison group (Behavioral); Bupropion (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
University of Kansas Medical Center
Primary completion
Dec 2010

Outcome Measures

OutcomeResultp-value
PRIMARY
7-day Point Prevalence Abstinence From Cigarettes
68; 56; 56 0.54
SECONDARY
Number of Quit Attempts
171; 160; 142; 2; 4; 3
SECONDARY
Progress in Stage of Change
24; 25; 15; 65; 74; 89

Summary

The primary aim of this study is to assess the effectiveness of both high and low intensity, disease management programs for smoking. The hypotheses are to compare abstinence from cigarettes, the number of quit attempts, and smokers motivation at 24 months between participants receiving high and low intensity disease management and those receiving usual care.

Eligibility Criteria

Inclusion Criteria

  • Over the age of 18
  • Reported smoking at least 10 cigarettes per day for at least 25 of the last 30 days
  • Speak English
  • Their regular physician is a participating physician
  • Working home telephone or cellular phone

Exclusion Criteria

  • Women who are pregnant or planning to become pregnant in the next two years
  • Plan on moving within two years
  • Display signs of dementia or other mental disorders
  • Live with a smoker already enrolled
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00440115). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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