Phase 4
Completed N=68
Nicotine Patch as an Analgesic Adjuvant After Surgery
Source: ClinicalTrials.gov NCT00440830 ↗Enrolled (actual)
68
Serious AEs
0.0%
Results posted
Oct 2010
Primary outcomePrimary: Postoperative Pain Score One Hour After Surgery — 5.78; 5.17; 4.32; 5.60 score on a scale
Summary
Effect of nicotine patch as an adjutant for acute pain after surgery.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Postoperative Pain Score One Hour After Surgery |
5.78; 5.17; 4.32; 5.60 | — |
| PRIMARY Postoperative Pain Score Five Days After Surgery |
2.24; 3.25; 1.38; 2.70 | — |
| SECONDARY Nausea Assessment by Patient |
0; 2.1; 0; 2.4 | — |
| SECONDARY Pain Medication Used |
75.2; 82.0; 41.9; 35.7 | — |
| SECONDARY Systolic Blood Pressure |
131; 127; 130; 136 | — |
| SECONDARY Diastolic Blood Pressure |
66; 80; 72; 65 | — |
| SECONDARY Heart Rate |
74; 83; 72; 78 | — |
Eligibility Criteria
Inclusion Criteria
- Adult ASA 1-2
Exclusion Criteria
- Cardiovascular disease
- Former smoker
- Pregnant
- Nursing
- Asthma
Data sourced from ClinicalTrials.gov (NCT00440830). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.