Phase 3 Completed N=143 Randomized Treatment

Extended Cessation Treatment for Teen Smokers

Nicotine Dependence

Source: ClinicalTrials.gov NCT00459953 ↗

Enrolled (actual)

143

Serious AEs

0.0%

Results posted

May 2016

Primary outcomePrimary: Point Prevalence Abstinence — 15; 5 participants

◆ Published Evidence

Established

23citations · ~2 / year

A randomized clinical trial of the efficacy of extended smoking cessation treatment for adolescent smokers.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2013 · Open access · High-confidence link

Full text ↗ PubMed 23460656 ↗

Summary

This study is designed to test the efficacy of an extended smoking cessation program for teen smokers. We hypothesize that teen smokers randomized to extended treatment will have a higher abstinence rate at 52 week follow-up than teen smokers receiving only open label treatment.

Linked Publications

A randomized clinical trial of the efficacy of extended smoking cessation treatment for adolescent smokers.

Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2013 · 23 citations · Open access · High-confidence link

Full text ↗PubMed 23460656 ↗

Outcome Measures

Outcome	Result	p-value
PRIMARY Point Prevalence Abstinence	15; 5	—

Eligibility Criteria

Inclusion Criteria

Age 14-18 at the beginning of the study

Smoking at least 10 cigarettes per day

At least one quit attempt in previous 6mos

Exclusion Criteria

Current DSM-IV disorder (depression, panic disorder, social anxiety disorder and agoraphobia)

Current self report of daily or heavy use (more than three times per week) of any drugs (marijuana, alcohol, cocaine, opiates, stimulants, etc.)

Positive urine pregnancy test

Currently on bupropion (Wellbutrin, Wellbutrin SR, Zyban) or other antidepressants, MAOI's, antipsychotics, benzodiazepines

Currently on NRT

Currently receiving formal treatment for substance abuse problem, depression or anxiety

View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00459953) and the linked publication. Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.