Mode
Home
Research
Clinical Trials Drug Pipeline Weekly Digests
Reference
Conditions Medications
Community
Questions
Text Size
Log in / Sign up
Home › Conditions › Nicotine Dependence

Nicotine Dependence

0 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Nicotine Dependence

137 trials tracked for Nicotine Dependence: 35 in phase 3 or 4 and 12 with published results. The most-cited published study has 183 citations.

137Trials tracked
35Phase 3 & 4
0Recruiting
12With published results
Phase distribution
Phase 4 21 Phase 3 14 Phase 2 39 Phase 1 10 Other / NA 53
  1. Phase 4 A Comparative Effectiveness & Long Term Health Study in Wisconsin Smokers Completed · 183 cited
  2. Phase 3 Varenicline for Adolescent Smoking Cessation Completed · 112 cited
  3. Phase 3 Maintaining Nonsmoking Completed · 72 cited
  4. Phase 3 Varenicline for Nicotine Dependence Among Those With HIV/AIDS Completed · 46 cited
  5. Phase 4 Varenicline for Nicotine Vaping Cessation in Adolescents Completed · 30 cited
  6. Phase 3 Extended Cessation Treatment for Teen Smokers Completed · 23 cited
Show 44 more trials
  1. Phase 3 Impact of Very Low Nicotine Content Cigarettes in a Complex Marketplace Completed · 22 cited
  2. Phase 4 Nicotine Replacement for Smoking Cessation During Pregnancy Completed · 21 cited
  3. Phase 4 Progesterone and Brain Imaging Study Completed · 12 cited
  4. Phase 4 Behavioral Activation and Varenicline for Smoking Cessation in Depressed Smokers Completed · 12 cited
  5. Phase 4 Research and Innovation to Stop E-cigarette/Vaping in Young Adults Completed · 4 cited
  6. Phase 3 Comparing NicoBloc to Nicotine Lozenges Completed
  7. Phase 4 Treatment of Nicotine Dependence and Acute Depression Completed
  8. Phase 4 Stress Neuroadaptation in Tobacco Dependence Completed
  9. Phase 4 Nicotine Dependence, Withdrawal and Replacement Therapy Assessed by PET Imaging Completed
  10. Phase 4 Bupropion for ADHD in Adolescents With Substance Use Disorder Completed
  11. Phase 4 Effects of Intranasal Oxytocin on Cigarette Smoking Completed
  12. Phase 4 Novel Pharmacotherapy Approaches in Smokers With Serious Mental Illness Completed
  13. Phase 4 Identifying Treatments to Motivate Smokers to Quit Completed
  14. Phase 4 Nicotine Replacement Therapy (NRT) and Bupropion Mechanisms of Effectiveness in Smokers Completed
  15. Phase 4 Evaluation of National Cancer Institute (NCI) Smoking Intervention Resources Completed
  16. Phase 4 Identifying Optimal Smoking Cessation Intervention Components (Cessation) Completed
  17. Phase 4 An Effectiveness Trial of Maintenance Therapy for Nicotine Dependence Completed
  18. Phase 4 Smoking Cessation Medications: Efficacy, Mechanisms and Algorithms Completed
  19. Phase 4 Measuring Smoking Behaviors While Using Varenicline Completed
  20. Phase 4 Helping Those With Mental Illness Quit Smoking Completed
  21. Phase 4 Evaluation of Treatments to Improve Smoking Cessation Medication Adherence Completed
  22. Phase 3 Mechanistic Evaluations of Pre-Cessation Therapies for Smoking Cessation Completed
  23. Phase 3 Sequential Use of Fluoxetine for Smokers With Elevated Depressive Symptoms Completed
  24. Phase 3 Extended Varenicline Treatment for Smoking Among Cancer Patients Completed
  25. Phase 3 Studying the Effects of Administration of Polyunsaturated Fatty Acids (PUFAS) of Omega-3 Series in Nicotine Dependence Completed
  26. Phase 3 Human Laboratory Study of Varenicline and Bupropion for Nicotine Dependence Completed
  27. Phase 3 New Treatment for Alcohol and Nicotine Dependence Completed
  28. Phase 3 Smoking-Cessation and Stimulant Treatment (S-CAST) Completed
  29. Phase 3 Concurrent Bupropion / Varenicline for Smoking Cessation Completed
  30. Phase 2 AXS-05 Phase II Trial on Smoking Behavior Completed
  31. Phase 2 Efficacy of Varenicline in Ambivalent Smokers Completed
  32. Phase 2 Treatment of Smoking Among Individuals With PTSD Completed
  33. Phase 2 Effects of Varenicline on Smoking Reminders Completed
  34. Phase 2 Zonisamide Augmentation of Varenicline Treatment for Smoking Cessation Completed
  35. Phase 2 A Controlled Laboratory Study of the Effects on Cue-Induced Craving in Dependent Smokers Completed
  36. Phase 2 Health Effects of SLT, Cigarette Smoking, and New Tobacco Products Completed
  37. Phase 2 St. John's Wort for Tobacco Cessation Completed
  38. Phase 2 Baclofen Effects in Cigarette Smokers Completed
  39. Phase 2 Evaluation of Moclobemide, a Reversible MAO-A Inhibitor, as an Adjunct to Nicotine Replacement Therapy in Female Smokers Completed
  40. Phase 2 Menstrual Cycle Effects on Smoking Cessation and Cue Reactivity Completed
  41. Phase 2 Selegiline for Smoking Cessation - 1 Completed
  42. Phase 2 Smoking, Sex Hormones, and Pregnancy Completed
  43. Phase 2 Gender Differences in Response to Nicotine Replacement Therapy and De-Nicotinized Cigarettes Completed
  44. Phase 2 Adaptive Pharmacotherapy for Smoking Cessation Completed

Showing the 50 most-cited and recently-updated of 137 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
No published articles yet for this condition. Check back soon.