Adrenal Function and Use of Intralesional Triamcinolone Acetonide 10 mg/mL (Kenalog-10) in Patients With Alopecia Areata

Inclusion Criteria

• Subject has clinical diagnosis of alopecia areata.
• Written informed consent and HIPAA authorization have been obtained.
• Female subjects of childbearing potential have a negative pregnancy test and agree to use an acceptable method of birth control to prevent pregnancy.
• In the opinion of the investigator, subject is a candidate for intralesional therapy for alopecia areata.
• Subject agrees to comply with protocol requirements and attend all required study visits and is considered to be a good study subject.
• Subject meets concomitant medication washout requirements.
• Subject is >/= 18 years of age.

Exclusion Criteria

• Subject has alopecia universalis.
• Subject has known adrenocortical insufficiency or Cushing's Syndrome.
• Subject is pregnant or lactating.
• Subject has current controlled or uncontrolled bacterial, viral, fungal, atypical, or opportunistic infections.
• Subject possesses hypersensitivity to cortrosyn or Triamcinolone Acetonide (Kenalog-10) or any component of their formulation.
• Subject is currently or has undergone therapy for malignancy within the past five years.
• Subject has history of substance abuse within the past five years.
• Subject has used oral corticosteroids within the past 12 months.
• Subject has concurrent use of phenytion rifampin, phenobarbital, mitotane, or other formulations of corticosteroid medications.
• Subject has any medical condition that, in the judgement of the investigator, would jeopardize the subject's safety following exposure to the administered medications.