Ivarmacitinib shows significant clinical improvement in a patient with alopecia areata and systemic lupus erythematosus
Ivarmacitinib Shows Promise for Alopecia Areata and Lupus Hair Loss
This case report and literature review describes a 35-year-old woman with severe patchy alopecia and systemic lupus erythematosus who showed…
A new treatment may help patients with overlapping hair loss conditions like alopecia areata and systemic lupus erythematosus.
Chronic dermatologic conditions significantly impact psychological distress and health-related quality of life in pediatric patients
Chronic skin conditions cause significant emotional distress in children
This systematic review of 41 studies examines the impact of chronic skin disorders on psychological outcomes and health-related quality of l…
Children with chronic skin conditions like psoriasis and eczema face high rates of anxiety, depression, and social struggles.
New consensus algorithm guides JAK inhibitor choice for alopecia areata
New treatment plan helps patients with hair loss condition
A guideline by expert dermatologists presents a consensus-based treatment algorithm for alopecia areata using SALT scores, quality-of-life i…
A new expert guide helps doctors choose the right medications for people and teens dealing with alopecia areata.
Upadacitinib Treatment for Concurrent Atopic Dermatitis Vitiligo and Alopecia Areata
One drug improved skin, hair, and pigment in one man
A 57-year-old man with severe, refractory skin conditions showed significant improvement in dermatitis, vitiligo, and hair loss on upadaciti…
A single patient with three skin conditions saw dramatic improvement after taking upadacitinib for one year.
Systematic review and meta-analysis on alopecia areata and skin cancer risk
Alopecia areata patients may have lower risk of certain skin cancers based on new review data
This systematic review and meta-analysis synthesized eight studies on skin cancer risk in patients with alopecia areata. The analysis found …
This review found that people with hair loss might have a lower chance of getting melanoma. Other skin cancers showed a similar trend but th…
Autoimmune Thyroiditis Prevalence Higher in Obese Women With PCOS in Retrospective Cohort Analysis
New PCOS Data Reveals Hidden Thyroid Risks
This retrospective cohort study evaluated 1,249 women with PCOS aged 18–44 years.
Women with PCOS should check their thyroid health regularly.
Baricitinib maintains SALT score ≤20 in adults with severe alopecia areata over 152 weeks
Baricitinib maintained hair regrowth in severe alopecia areata for over three years in this trial
This phase 3 RCT evaluated continuous baricitinib in 196 adults with severe alopecia areata.
Baricitinib kept hair growing on the scalp, eyebrows, and eyelashes for over three years in adults with severe alopecia areata who responded…
Deuruxolitinib 8 or 12 mg BID improved SALT20 response versus placebo in severe alopecia areata
Hair Regrowth Drug Shows Strong Results in Major Trial
This Phase 3 randomized, double-blind, placebo-controlled, multicenter trial enrolled 517 adults aged 18 to 65 years with severe chronic alo…
A new drug helped 38% of adults with severe hair loss regrow most of their hair in just six months during a major trial.
Phase 2 trial finds topical STS01 1% improves SALT scores in patchy alopecia areata
A New Topical Treatment Shows Promise for Patchy Hair Loss
A phase 2 randomized controlled trial in 155 adults with mild to moderate patchy alopecia areata found that daily topical STS01 1% for 6 mon…
A new, easy-to-apply cream could offer a much-needed treatment option for a common and distressing form of autoimmune hair loss.
Centralized hair loss measurement showed better agreement and 50% lower error margins than local rating in mild-to-moderate Alopecia Areata
Centralized hair loss scoring showed better consistency than local ratings in mild Alopecia Areata trials
This Phase 2 clinical trial compared centralized measurement of hair loss via standardized photographic images against local SALT score rati…
Centralized hair loss scoring cut measurement errors by half compared to local ratings in mild Alopecia Areata trials, boosting trial succes…
Phase 2 trial: Topical STS01 shows dose-related hair regrowth in mild-moderate alopecia areata
Topical treatment shows hair regrowth in alopecia areata, but quality of life unchanged
A Phase 2 randomized controlled trial in patients with mild to moderate patchy alopecia areata found that topical STS01 (dithranol) produced…
A new topical treatment regrows hair in patchy alopecia, yet patients report no improvement in daily life or feelings even with full regrowt…
Phase 3 trial of low-dose IL-2 versus placebo for severe alopecia areata completed in 44 patients
Phase 3 trial tests low-dose IL-2 for severe alopecia areata, results pending
A Phase 3, prospective, randomized, double-blind, multicenter trial compared low-dose IL-2 to placebo in 44 patients with severe alopecia ar…
A major late-stage trial testing low-dose IL-2 for severe alopecia areata has finished, but results on hair regrowth are not yet available.
Research across Androgenetic alopecia
Related studies from across the Androgenetic alopecia family.
5-alpha-reductase inhibitors show no statistically significant association with suicide or neuropsychiatric events in BPH or AGA
Trial shows 5-alpha-reductase inhibitors do not increase suicide risk
This meta-analysis of observational studies examined the risk of suicide and neuropsychiatric events in patients with benign prostatic hyper…
New data suggests that 5-alpha-reductase inhibitors for hair loss or prostate issues are not linked to higher rates of suicide or depression…
Inflammation and fibrosis coupling contribute to hair follicle miniaturization in androgenetic alopecia
Inflammation and Fibrosis Linked to Hair Loss in Male Pattern Baldness
This mini-review explores the role of inflammation and fibrosis in androgenetic alopecia. The authors identify specific immune-enriched tran…
New research highlights how inflammation and tissue scarring may play a key role in why some people experience hair loss in androgenetic alo…
5-alpha-reductase inhibitors are associated with increased sexual adverse events in androgenetic alopecia patients
Hair loss medications may cause some side effects for men
This systematic review of 41 studies evaluates the impact of finasteride and dutasteride on sexual dysfunction in patients with hair loss. T…
Men using finasteride or dutasteride for hair loss may experience sexual side effects, though most cases are mild and reversible when the dr…
Pilot Study Shows 2% Salicylic Acid Shampoo Reduces Scab Severity in Androgenetic Alopecia Patients
Simple wash removes scabs after hair transplant surgery
This prospective, multicenter, single-arm pilot study evaluated 21 male patients using a 2% salicylic acid shampoo.
A new shampoo formula helps clear scabs after hair transplant surgery without causing pain or irritation for most patients.
Questions about Alopecia Areata
Is there evidence that upadacitinib helps treat concurrent Vitiligo and alopecia areata?
Yes, a case report shows upadacitinib 15 mg daily improved vitiligo repigmentation and alopecia areata hair regrowth in a patient with both conditions.
Full answer →Is the topical treatment STS01 effective for patchy alopecia areata?
Yes, a phase 2 trial found that topical STS01 1% significantly improved hair regrowth in patchy alopecia areata compared to placebo.
Full answer →Does having alopecia areata increase or decrease my risk of getting skin cancer?
Alopecia areata is linked to a lower risk of melanoma and possibly other skin cancers, not an increased risk.
Full answer →