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Phase 4 N=79 Randomized Double-blind Treatment

Study of Two Marketed Ocular Anti-Allergy Medications in Subjects With Allergic Conjunctivitis

Allergic Conjunctivitis

Enrolled (actual)
79
Serious AEs
Results posted
May 2009
Primary outcome: Primary: Change in Ocular Itch Score From Baseline — -1.5; -1.5 units on a scale — p=0.532

Study Design & Population

Study type
Interventional
Phase
Phase 4
Interventions
Elestat (Drug); Pataday (Drug)
Age
Adult, Older Adult · 18+ yrs
Sex
All
Sponsor
Merck Sharp & Dohme LLC
Primary completion
Jan 2008

Outcome Measures

OutcomeResultp-value
PRIMARY
Change in Ocular Itch Score From Baseline
-1.5; -1.5 0.532
SECONDARY
Ocular Comfort Score at 12 Hours
8.6; 8.5 0.927

Summary

The purpose of this study is to compare the effects of two marked ocular anti-allergy medications in cat sensitive subjects with allergic conjunctivitis.

Eligibility Criteria

Inclusion Criteria

  • Documented history of ocular allergy to cats.
  • Positive skin prick allergen reaction to cat dander.

Exclusion Criteria

  • Use of any topical or systemic corticosteroids, immunosuppressive agents, antihistamines, decongestants, NSAIDs, or asprin during the two weeks prior to enrollment into the study.
  • History of severe asthma, reactive airway disease or bronchial obstruction.
  • Ocular surgery or trauma in the last year.
View full record on ClinicalTrials.gov →

Data sourced from ClinicalTrials.gov (NCT00534794). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.

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