N/A
N=32
Impaired Regulation of Energy Balance in Elderly People (Balance Study)
Anorexia of Ageing
Bottom Line
View on ClinicalTrials.gov: NCT00561145 ↗Enrolled (actual)
32
Serious AEs
0.0%
Results posted
Mar 2016
Primary outcome: Primary: Energy Intake Compensation — 1; 1 MJ/day
Study Design & Population
- Study type
- Interventional
- Phase
- N/A
- Interventions
- Energy restriction period (Other)
- Age
- Adult, Older Adult · 20+ yrs
- Sex
- Male
- Sponsor
- Wageningen University
- Primary completion
- Mar 2010
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Energy Intake Compensation |
1; 1 | — |
| SECONDARY Appetite/Satiety Hormones and Questionnaires |
— | — |
| SECONDARY Gastrointestinal Function |
— | — |
| SECONDARY Resting Energy Expenditure, Body Composition and Body Weight |
— | — |
| SECONDARY Expression of Genes Involved in Energy Metabolism |
— | — |
Summary
Over the past century life expectancy has risen rapidly. As a result, the proportion of elderly people continues to grow. Elderly people probably have an impaired regulation of energy balance (energy intake versus energy expenditure) whereby the underlying physiological mechanisms are not fully understood.
The first objective of this study is to provide further evidence for an age-related failure to regulate energy balance in elderly. If the hypothesis of impaired regulation of energy balance in elderly is confirmed then the second objective becomes to elucidate the underlying physiological mechanisms of the age-related failure to regulate energy intake in elderly.
Eligibility Criteria
Inclusion Criteria
- men
- healthy
- 20-40 and 65-85 years of age
- normal weight
- free-living in Wageningen and surrounding
Exclusion Criteria
- anemia
- diabetes
- restrained eating
- dementia
- weight changes of > 2 kg during the last 2 months
Data sourced from ClinicalTrials.gov (NCT00561145). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication.