N/A N=32 Impaired Regulation of Energy Balance in Elderly People (Balance Study)
Anorexia of Ageing
Primary: Energy Intake Compensation — 1; 1 MJ/day
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=5 Ghrelin Dose Finding In Frail Elderly
The Frailty Syndrome
Primary: Treatment Emergent Adverse Events — 1; 0; 1; 0 Events
N/A N=15 Cancer Anorexia and the Central Nervous System
Cancer Cachexia
Primary: ACTIVATION/NON ACTIVATION OF SPECIFIC BRAIN AREAS, EVALUATED BY FUNCTIONAL MAGNETIC RESONANCE — 585.57; 667.92; 511.22 BOLD
N/A N=40 Assessment of Body Composition and Physical Function
Body Composition · Physical Function
Primary: Fat Mass — 44.71 Kg
Phase 2 N=5 Ghrelin Repeated Dose Study
Frailty in Aging
Primary: Safety — 4 participants
Phase 3 N=164 Calorie Restriction and Changes in Body Composition, Disease, Function, and Quality of Life in Older Adults
Obesity · Diabetes · Hypertension
Primary: Change in Abdominal Fat Mass — -192.6; -21.9; -275 Cubic cm
N/A N=82 IGF-1 and Bone Loss in Women With Anorexia Nervosa
Anorexia Nervosa · Osteopenia · Osteoporosis
Primary: Postero-anterior Spine Bone Mineral Density by DXA — 0.891; 0.887; 0.874 g/cm2 — p=0.03
N/A N=152 Olanzapine Versus Placebo for Outpatients With Anorexia Nervosa
Anorexia Nervosa
Primary: Rate of Weight Change — 0.095; 0.260 kg/m^2 per month
Phase 3 N=75 Effects of Anorexia Nervosa on Peak Bone Mass
Anorexia Nervosa
Primary: Change in Bone Density Over a 12-month Period — 0.045; 0.280 score on a scale — p=.109
Phase 3 N=110 Effects of Anorexia Nervosa on Bone Mass in Adolescents
Anorexia Nervosa
Primary: Percent Change in Spine Bone Density Over the Study Duration (18 Months) — 2.6; 0.3 Percent change — p=<0.05
Phase 2 N=16 Ghrelin Plus Strength Training in Frail Elderly Study
Frailty Syndrome
Primary: Change in the Short Physical Performance Battery (SPPB) — 0.6; 2.4 units on a scale
Phase 3 N=77 Bone Loss in Women With Anorexia Nervosa
Anorexia Nervosa
Primary: Bone Mineral Density — 3.2; -0.6 percent change — p=<0.0001
N/A N=30 Nutritional Biomarkers of Sarcopenia
Sarcopenia
Primary: Resting and Maximum Plasma Leucine Concentration — 659; 755; 721; 95 micromoles per liter
N/A N=177 Shifting Perspectives: Enhancing Outcomes in Anorexia Nervosa With CRT
Anorexia Nervosa
Primary: Change in Cognitive Flexibility - Condition 4 Trail Making Test of DKEFS — 11.89; 10.94; 11.47; 11.14 score on a scale — p=.507
Phase 2 N=10 Ghrelin in Healthy and Frail Older Women
Frailty
Primary: Kilocalories Consumed — 412; 553 Kilocalorie
N/A N=96 Effect of High Protein Weight Loss for Seniors
Obesity · Weight Loss
Primary: Change in 400 Meter Gait Walk Speed — 0.01; -0.02 meters/second
N/A N=9 Translational Control of Anabolic Resistance in Aging Muscle
Physical Inactivity
Primary: Lean Mass — 403 grams
N/A N=20 Preventing the Loss of Muscle and Function in Hospitalized Older Adults
Muscular Atrophy
Primary: The Percent Change in Bilateral Thigh Lean Mass Density (Grams) as Measured by DEXA Scan Will be Compared Between Baseline and After 5-days of Bed Rest — -3.845; -0.249…
N/A N=44 Maximizing the Dietary Pattern of Older Adults: the Effects of Protein Intake on Protein Kinetics
Sarcopenia
Primary: Whole Body Protein Turnover — -0.16; -0.17; 0.48 g/kg lean body mass/day
N/A N=47 Nutritional Intake of "Finger-food" on Elderly People in Seniors's Resident
Nutritive Value
Primary: Quantitative Measure of Ingesta — 941.1; 910.1; 1001; 862.9 Kilocalories — p=<0.0001
N/A N=16 Effect of an EAA/Whey Composition on Protein Metabolism
Sarcopenia
Primary: Protein Anabolism — 3.56; 11.8; 3.02 grams — p=<0.05
N/A N=446 PEU in Elderly TCU Residents
Aging
Primary: Percentage of Subjects With Average Daily Nutrient Intake <70% of Predicted Needs — 26 percentage of subjects
N/A N=76 Integrated Physical Training With Protein Diet in Older Adults With Sarcopenia Symptoms.
Sarcopenia
Primary: Changes in Hand Grip Strength — 29.2; 29.5; 35.3; 30.3 kg — p=<0.05
N/A N=33 Young Adult Eating Habits
Eating Behavior · Eating Habit
Primary: Change in Brain Response From Baseline to 2-weeks Post High UPF or 2 Weeks no UPF Diet — 0.02; 0.13 arbitrary units
Phase 2 N=11 Transdermal Estrogen in Older Premenopausal Women With Anorexia Nervosa
Anorexia Nervosa · Osteoporosis
Primary: Percent Change in Bone Mineral Density (BMD) of Lumbar Spine by Dual Energy X-ray Absorptiometry (DXA) — 2.0 percent change
Phase 2 N=28 Effects of rhIGF-1 on Bone Metabolism in Adolescent Girls With Anorexia Nervosa
Disorder of Bone Density and Structure, Unspecified
Primary: Change in Spine Bone Density (g/cm^2) — -0.00558 gm/cm^2 — p=0.40
Phase 2 N=23 The Role of Parathyroid Hormone (PTH) in Low Bone Mass in Anorexia Nervosa
Anorexia Nervosa · Osteoporosis
Primary: Percent Change in Lumbar Spine Bone Mineral Density — 5.6; 0.2 percentage of change — p=< 0.01
N/A N=105 Protein Supplementation in Elderly With Sarcopenic Obesity Undergoing Caloric Restriction and Exercise
Sarcopenic Obesity · Aging
Primary: Percentage of Fat-free Mass — 49.6; 50.3; 50.5; 52.5 percentage of fat-free mass — p=0.013
Early Phase 1 N=13 Dopamine Receptor Contributions to Prediction Error and Reversal Learning in Anorexia Nervosa
Anorexia Nervosa
Primary: Measurement of Brain Activation (Measured in Percent Signal Change) During a Prediction Error Taste Reward Task Using Functional Magnetic Resonance Imaging (fMRI)…
Phase 4 N=41 A Double-blind, Placebo Controlled Trial of Risperidone for the Treatment of Anorexia Nervosa
Anorexia Nervosa
Primary: Change in Eating Disorder Inventory-2 Drive for Thinness Subscale (DT) — 1.36; 3.93 units on a scale