Phase 2
Completed N=21
Treatments for Recovery of Hand Function in Acute Stroke Survivors
Source: ClinicalTrials.gov NCT00565045 ↗Enrolled (actual)
21
Serious AEs
0.0%
Results posted
Jul 2013
Primary outcomePrimary: Maximum Voluntary Finger Extension Angle (a Measure of Hand Impairment) — -11.6; -43.4 degrees
Summary
Impaired hand function is one of the most frequently persisting consequences of stroke. The purpose of this study is to investigate whether two different types of treatment improve recovery of hand function after stroke.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Maximum Voluntary Finger Extension Angle (a Measure of Hand Impairment) |
-11.6; -43.4 | — |
| SECONDARY Finger Tracking Error |
4.7; 8.3 | — |
| SECONDARY Box and Blocks Score |
29.8; 22.9 | — |
| SECONDARY Arm Motor Abilities Test |
3.54; 3.20 | — |
| SECONDARY Fugl-Meyer Assessment (Upper Extremity) |
46.2; 41.1 | — |
Eligibility Criteria
Inclusion Criteria
- Age 18 to 80
- Within 6 months of first clinical hemorrhagic or nonhemorrhagic stroke
- Cortical or subcortical stroke
- Unilateral upper extremity hemiparesis with severe finger extensor and flexor paresis ( = 13 on Beck Depression Inventory Fast Screen)
- Ipsilateral lower motor neuron lesion
- Parkinson's Disease
- Spinal cord injury
- Traumatic brain injury
- Multiple sclerosis
- Lack of functional passive range of motion of the wrist or fingers of affected side
- Severe shoulder or hand pain (unable to volitionally position hand in the workspace without pain)
- Intramuscular botulinum toxin injections in upper extremity muscle in the last 3 months
Data sourced from ClinicalTrials.gov (NCT00565045). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.