Stroke

All Stroke Articles

• Cortical atrophy (GCA 1 vs. 0) associated with lower functional independence in women with ischemic stroke
• Blood GFAP levels provide high specificity for identifying intracerebral hemorrhage in acute stroke patients
• taVNS Improves Memory in Rodent Stroke Models With Large Pooled Effect
• LLM-based risk-of-bias assessments show limited agreement with human reviewers in neurology prognosis studies
• Tenecteplase and alteplase improve functional outcomes in extended windows but increase symptomatic intracranial hemorrhage risk
• Adjunctive acupoint application increases clinical response rates in post-stroke sleep disorders
• Obstructive sleep apnea is associated with a 2- to 3-fold increase in stroke risk
• Detectable Microembolic Signals on TCD Linked to 2.85-Fold Higher Odds of Poor Stroke Outcome
• Acupuncture-based interventions improve Fugl-Meyer Assessment scores for post-stroke foot drop compared to conventional treatment
• Transcranial direct current stimulation combined with cognitive training yields largest improvements in post-stroke cognitive function
• Non-invasive brain stimulation shows favorable tolerability and 94.9% completion rate for post-stroke upper limb rehabilitation
• Robotics-based interventions show stronger evidence for improving upper-limb motor function after stroke
• Robot-Assisted Stroke Rehab May Improve Balance, Review Finds
• Bright light therapy improves subjective sleep quality in adults with stroke
• IL-34/CSF1R signaling modulates CNS immune cell development and impacts neurodegenerative disease progression
• Leisure rehabilitation improves participation in stroke survivors, but evidence is low certainty
• Paired vagus nerve stimulation with task-specific rehabilitation improves durable upper-limb outcomes in chronic ischemic stroke
• Wearable digital biomarkers show potential for neurorehabilitation monitoring, but evidence is heterogeneous and early
• Mobile stroke units cut critical time metrics by 26.3 minutes in acute stroke
• BCI-based interventions improve FMA-UE scores in patients with stroke and poststroke hemiplegia
• Tai Chi provides positive effects for balance, mood, and cognitive performance in older adults
• Sarcopenia and Low Grip Strength Correlate with Increased Cardiovascular Risk in Older Adults
• Mothership strategy increases likelihood of achieving 90-day mRS 0 to 2 in AIS-LVO patients
• Specific traditional Chinese medicine formulations show varied outcomes in patients with ischemic stroke
• Evaluating Thrombectomy Efficacy and Safety in Patients with Medium or Distal Arterial Occlusions
• No-reflow phenomenon affects at least 25% of patients after reperfusion in acute ischemic stroke
• Efficacy of Intravenous Thrombolysis for Acute Ischemic Stroke Patients Late in Window
• Intravenous tirofiban before endovascular treatment increases risk of parenchymal hematoma type 2
• Tenecteplase shows higher mRS 0 to 1 rates in distal M3 and beyond occlusions
• Prehospital magnesium sulfate shows no significant overall clinical benefit in acute ischemic stroke
• Dual antiplatelet therapy reduces major ischemic events in week 1 of minor stroke or TIA
• Early oral anticoagulants show no significant difference in stroke risk compared to late initiation
• Exercise-based cardiac rehabilitation improves aerobic capacity and systolic blood pressure in stroke and TIA patients
• Traditional Chinese Exercises improve sleep quality and reduce anxiety and depression in post-stroke survivors
• ENTF brain stimulation improves freedom from disability in subacute ischemic stroke patients
• Clopidogrel plus aspirin for 21 days provides favorable net clinical benefit in minor ischemic stroke
• BCI-based training yields statistically robust but clinically modest improvements in post-stroke lower-limb motor function
• High Lp-PLA2 levels triple recurrent stroke risk in ischemic stroke patients
• Eighteen assessment tools exist for identifying and managing stroke-related sarcopenia in clinical practice
• Loberamisal doses of 20mg, 40mg, and 60mg show no significant difference from placebo
• Machine learning models show high AUC for predicting stroke-related dysphagia and aspiration risks
• Intra-arterial alteplase trial protocol for large vessel occlusion stroke aims to improve outcomes
• Phase 3 Trial Protocol Evaluating Intravenous Loberamisal for Acute Ischaemic Stroke Management
• BNT162b2 vaccination shows no significant increase in stroke risk in meta-analysis
• Music-based interventions significantly improve gait speed and motor function in patients with stroke
• iNKT cell activators show promise in preclinical models for stroke-associated pneumonia immunomodulation
• Stimuli-responsive nanozyme-hydrogel systems offer a design framework for ischemic stroke therapy, but direct evidence remains limited
• Risk prediction models show AUC of 0.85 and 0.82 for post-stroke cognitive impairment
• High-risk perfusion phenotypes correlate with early neurological deterioration and poor functional outcomes in low-NIHSS LVO stroke
• Edaravone dexborneol reduces NIHSS scores by 2.27 compared to control in acute ischemic stroke
• Transcranial direct current stimulation results for upper limb spasticity after stroke remain inconclusive
• Adding antiplatelet therapy to anticoagulation does not cut stroke risk but raises major bleeding
• Electroacupuncture improves neurological function and reduces infarct volume in animal models of ischemic stroke
• Acupuncture improves symptom scores and vertebrobasilar blood flow in patients with posterior circulation ischemic vertigo
• BCI-mediated rehabilitation improves upper limb motor function and MBI scores after stroke
• Traditional Chinese medicine may activate Wnt/beta-catenin signaling pathways in cerebral ischemia and reperfusion injury
• Xenon shows strongest evidence for neuroprotection against ischemic stroke and hypoxic-ischemic brain injury
• Thrombolysis prior to endovascular thrombectomy increases 90-day functional independence (RR 1.12) in large-vessel stroke
• Elevated head position does not significantly improve 90-day functional outcomes after endovascular thrombectomy
• Tenecteplase Combined With Thrombectomy Improves Functional Outcomes in Low ASPECTS Stroke Patients
• Idarucizumab-mediated reversal of dabigatran before thrombolysis shows 66.6% good functional outcome at 90 days
• Mechanical thrombectomy shows potential for favorable outcomes in pediatric large-vessel occlusion stroke
• Genetic risk scores for Primary Aldosteronism identify blood pressure independent pathways for cardiovascular disease
• Personal, environmental, and behavioral factors influence digital health literacy among stroke patients
• Seven genome-wide significant loci and eight HLA alleles associated with shingles susceptibility identified
• Chinese stroke policy shows three-stage progression toward system-embedded and quality-oriented governance structures
• Multifaceted Experiences and Management Strategies for Patients Living with Post-Stroke Fatigue
• Statistical Plan for PES Trial in Post-Stroke Dysphagia
• Infratentorial lesions result in 58% dizziness prevalence in acute ischemic stroke patients
• Individualized blood pressure control does not improve outcomes in acute ischemic stroke patients
• Higher FIB-4 scores are associated with increased odds of poor stroke outcomes and mortality
• Endovascular treatment under conscious sedation associated with worse outcomes than best medical treatment
• Community health worker-led interventions reduce systolic blood pressure by 5.5 mm Hg
• Prediabetes combined with malignant LVH increases stroke risk by HR 3.07 in hypertensive adults
• Stroke Riskometer app fails to improve Life's Simple 7 score at 6 months
• Ultra-early RIPC does not significantly improve 90-day functional independence in acute ischemic stroke
• Association of MTHFR C677T Polymorphism with Risk of Lacunar Infarction
• Acupuncture and related therapies improve Pittsburgh Sleep Quality Index scores in post-stroke insomnia
• Ultrasound Stimulation Boosts Stroke Rehab Outcomes
• Intravenous thrombolysis improves functional outcomes in patients with acute ischemic stroke after 4.5 hours
• Endovascular thrombectomy is effective for specific large-vessel occlusion and late-window ischemic stroke scenarios
• GWAS meta-analysis identifies 44 TIA loci, 19 specific to transient ischemic attack
• Thirty-two factors including low BMI, advanced age, and frailty are associated with stroke-related sarcopenia
• Thromboembolic events cost 2.5-fold more per event than bleeding after high-risk endoscopy
• Impact of Infarct Volume on Safety and Efficacy of Early DOAC Initiation
• Early Emotional Interventions Boost Stroke Recovery Outcomes
• Bilateral training improves motor function in post-stroke patients with distal upper extremity hemiplegia
• Cardiac CT detects thrombi in 6.2% of acute stroke patients, outperforming echocardiography
• Higher admission neutrophil-to-lymphocyte ratio (NLR) associated with unfavorable functional outcomes in acute ischemic stroke
• Tenecteplase improves functional outcomes and early neurological recovery in late window acute ischemic stroke
• Hydrokinesitherapy improves balance function in stroke survivors across multiple assessment measures
• Tirofiban as an adjunct to endovascular thrombectomy is safe and effective for large vessel occlusion
• Cognitive Behavioral Therapy for Managing Fatigue Severity in Adult Stroke Survivors
• Intravenous thrombolysis combined with endovascular treatment improves 90-day functional independence in tandem lesion stroke
• DOAC therapy reduces odds of symptomatic ischemic stroke compared to aspirin monotherapy
• Anticoagulation associated with lower risk of recurrent stroke in patients with left ventricular systolic dysfunction
• Combined Mirror Therapy and Transcranial Direct Current Stimulation for Poststroke Upper Limb Recovery
• Early implantable cardiac monitor placement improves atrial fibrillation detection rates in cryptogenic stroke patients
• Implantable cardiac monitors detect 21.3% prevalence of atrial fibrillation in post-stroke patients
• Fire Dragon Cupping may improve clinical efficacy in post-stroke shoulder-hand syndrome
• Elevated neutrophil-to-lymphocyte ratio correlates with greater cerebral small vessel disease burden and white matter hyperintensities
• Network meta-analysis protocol plans to evaluate brain-computer interface feedback modes for post-stroke upper-limb motor impairment
• Evolocumab plus statin protocol targets early neurological deterioration in acute ischemic stroke
• Tigertriever associated with higher reperfusion rates in large vessel occlusion stroke compared to stent-retrievers
• Intra-arterial alteplase and tenecteplase improve excellent functional outcomes after endovascular thrombectomy for stroke
• Liraglutide reduces stroke recurrence from 18.1% to 5.8% in patients with high insulin resistance
• Ischemic stroke patients exhibit distinct gut microbiota profiles and altered functional pathways
• Lower aspirin doses combined with clopidogrel may reduce ischemic events in high risk patients
• Third-wave therapies significantly reduce post-stroke depression symptoms with sustained mid- to long-term effects
• In-hospital delays before reperfusion correlate with worse outcomes in patients undergoing endovascular thrombectomy
• Low ADAMTS13 activity linked to ischemic stroke in meta-analysis of 8,993 patients
• Maladaptive responses to chronic hypoxia at high altitude increase ischemic stroke risk through thrombogenesis
• General anesthesia improves functional independence and reperfusion in patients undergoing endovascular thrombectomy for ischemic stroke
• Protocol for systematic review and meta-analysis of Dynamic Scalp Acupuncture for motor function after stroke
• Deep learning achieves expert-level accuracy in stroke imaging analysis, review finds
• 21% hypertension prevalence in transgender adults: meta-analysis of cardiovascular morbidities
• Early tirofiban improves functional outcomes in non-DM ischemic stroke patients but not in DM
• Trial protocol for intra-arterial alteplase in anterior circulation large-vessel occlusion ischaemic stroke
• Combined tDCS and mirror therapy improves upper limb function and activities of daily living after stroke
• Patients with cardiovascular diseases show measurable prevalence of active cancer across multiple conditions
• Operator device-selection preference did not correlate with superior first-pass effect rates in stroke thrombectomy
• Mechanical thrombectomy increases parenchymal hematoma risk but maintains better functional outcomes
• Route 92 Reperfusion System increases first-pass effect and near-complete reperfusion in acute ischemic stroke
• Cognitive frailty prevalence among older adults with stroke is 33% with higher rates in those aged 80+
• Traditional Chinese exercises significantly improve motor function and balance in stroke survivors across various stages
• HIIT and MICT improve fitness and walking after chronic stroke, but balance evidence is low
• Early DAPT associated with higher excellent functional outcome in minor stroke patients with history of DM
• Bridging therapy increases parenchymal hemorrhage risk by 2.36 OR in patients with BGI
• Immediate antihypertensive treatment for acute ischemic stroke may increase risks in specific blood pressure subgroups
• rTMS alleviates post-stroke spasticity and improves motor function in patients with upper limb involvement
• Transcranial magnetic stimulation improves upper limb function and motion in post-stroke patients
• Stroke etiology does not modify the efficacy of intravenous thrombolysis before endovascular treatment
• Apixaban reduces stroke and systemic embolism in patients with subclinical atrial fibrillation and an implantable cardiac monitor
• Thrombolysis plus endovascular therapy for basilar artery occlusion: a trial protocol
• Intensive blood pressure lowering reduces severe cerebral oedema risk in acute ischemic stroke patients
• Cocaine and amphetamine use significantly increase stroke risk as confirmed by Mendelian randomization
• Botulinum toxin reduces spasticity in adult stroke survivors but shows inconsistent benefits for gait and balance
• Efficacy of Levodopa Based Therapy for Motor and Cognitive Recovery After Stroke
• Evaluating High Frequency Repetitive Transcranial Magnetic Stimulation for Post Stroke Cognitive Impairment
• Non-immersive virtual reality combined with conventional therapy improves upper limb function and activities of daily living
• Dual antiplatelet therapy reduces stroke recurrence in patients with acute mild ischaemic stroke
• Demographic and clinical factors associated with poststroke cognitive impairment in stroke patients
• Intervention Mapping framework supports development of tailored behavioral interventions for stroke survivor rehabilitation
• Transcranial Magnetic Stimulation reduces motor overflow in focal dystonia and improves stroke and cerebral palsy outcomes
• DAPT and aspirin show potential for managing minor acute ischemic stroke based on SUCRA rankings
• Multidimensional biomarker panels suggest a complex pathological basis for post-stroke depression in the DRN-mPFC circuit
• Ligustilide shows neuroprotective effects across multiple CNS disorders in preclinical models
• Intravenous thrombolysis does not improve excellent functional recovery in patients with minor acute ischemic stroke
• Transitional care interventions reduce rehospitalization and improve quality of life in adult stroke survivors
• Endovascular treatment does not improve functional outcomes but increases symptomatic intracranial hemorrhage risk in low NIHSS stroke
• Adjunctive neuroprotective pharmacotherapy shows modest increase in functional independence for patients with acute ischemic stroke
• Neuroinflammation-targeted immunotherapy shows no significant benefit in ischemic stroke meta-analysis
• EMG-based bioelectrical feedback improves Fugl-Meyer scores by 9.50 points in post-stroke hemiplegia
• Tenecteplase shows no significant difference in serious adverse event distribution compared to alteplase
• Vasospasm after thrombectomy may signal microvascular failure needing vasodilators
• PINGS intervention improves systolic blood pressure control to 67% compared to 43% in usual care
• rTMS interventions significantly reduce modified Ashworth Scale scores for post-stroke limb spasticity
• Individualized six-phase antithrombotic strategy leads to left ventricular thrombus resolution and neurological recovery
• Mind-body training improves upper-limb function after stroke, optimal dose near 33.5 hours
• Tirofiban Adjunct Therapy Improves Outcomes in Patients with Inadequate Tenecteplase Response
• Acupuncture shows consistent signals for dysphagia and depressive symptoms after ischemic stroke
• Brain-computer interface training improves global cognitive function in stroke survivors with SMD=0.62
• Repetitive transcranial magnetic stimulation may enhance upper limb motor function following a stroke
• Localized AI and policy frameworks address structural barriers to stroke care in low-income countries
• Endothelial ferroptosis blockade targets ischemic stroke and neurodegenerative conditions in brain microvascular endothelial cells
• Meta-analysis shows tirofiban improves functional independence but raises intracranial hemorrhage risk in acute ischemic stroke patients
• High SII at admission linked to 2.14-fold increased risk of post-stroke depression
• Remote transitional care improves depressive symptoms in stroke patients, meta-analysis finds
• Triple Pill Therapy Lowers Recurrent Stroke Incidence in Patients With Prior Intracerebral Hemorrhage
• Tenecteplase before EVT shows no functional benefit over EVT alone in late window stroke
• Non-invasive brain stimulation with motor imagery improves upper limb function after stroke with WMD 5.75
• Thrombectomy plus intra-arterial alteplase increases excellent functional outcome to 57.5% at 90 days
• Higher admission WBC predicts favorable methylprednisolone effect after thrombectomy
• Apixaban Reduces Intracranial Bleeding Risk Compared To Aspirin In Patients With Cryptogenic Stroke And Atrial Cardiopathy Evidence
• Post hoc analysis shows unsuccessful thrombectomy does not worsen outcomes for large ischemic infarcts compared to medical treatment alone
• Higher EAT-Lancet diet adherence linked to lower risks of depression, anxiety, stroke, and dementia in observational cohorts
• Intracranial hemorrhage rates were higher in tenecteplase than standard care at 14.4% versus 9.2% in minor ischemic stroke
• Endovascular therapy showed no benefit over medical care alone for mild-to-moderate medium or distal vessel occlusion stroke patients in this randomized trial
• Interactive cognitive-motor training improves mobility, gait, and balance in chronic stroke
• Extended-window alteplase increases functional outcomes but raises hemorrhage risk in acute ischemic stroke patients
• Endovascular thrombectomy boosts functional independence significantly for acute ischemic stroke patients compared to medical management alone
• Nurse-driven service model reduces door-to-needle time by 16.72 minutes in acute ischemic stroke
• PFO closure reduces recurrent stroke risk by 44% in older patients with cryptogenic stroke
• NINJ1 targeting shows potential for multiple sclerosis and other neurological conditions but faces significant knowledge gaps
• Atractylenolide III shows neuroprotective effects in preclinical CNS disorder models
• Non-invasive neural stimulation improves upper limb function in subacute stroke: meta-analysis
• Network meta-analysis compares alteplase, tenecteplase, and JX10 for acute ischemic stroke treatment outcomes
• Protocol outlines planned network meta-analysis of electromagnetic stimulation for post-stroke lower limb dysfunction
• Meta-analysis suggests specific rTMS protocols improve cognitive and functional outcomes in stroke survivors
• Meta-analysis of exercise for post-stroke cognitive impairment shows cognitive and motor benefits
• IV tenecteplase beyond 4.5 hours shows modest benefit but higher bleeding risk in acute ischemic stroke patients
• Case report details treatment of ANCA-associated vasculitis with Evans syndrome and cerebral infarction in a 72-year-old woman
• Breast arterial calcification linked to increased cardiovascular mortality risk
• Evidence summary on glycemic variability management in ICU patients with cerebral infarction
• Network meta-analysis reviews acupuncture for post-stroke spasticity
• Review synthesizes neuroprotective potential of TCM metabolites using zebrafish models for neurological conditions
• Systematic review and meta-analysis of ACT-based interventions for depression in stroke patients
• Pre-infection vaccination linked to lower cardiovascular and cerebrovascular event risks in SARS-CoV-2 infected individuals
• Endovascular thrombectomy improves outcomes in large-core stroke within 24 hours
• Systematic review and meta-analysis of AI for post-stroke epilepsy prediction and diagnosis