N/A
Completed N=450
Treatment of Schizophrenic Patients With Ziprasidone
Source: ClinicalTrials.gov NCT00579670 ↗Enrolled (actual)
450
Serious AEs
0.4%
Results posted
May 2010
Primary outcomePrimary: Summary of Schizophrenia — 1; 5; 9; 39 Participants
Summary
To determine whether ziprasidone provides good efficacy and tolerability in the treatment of schizophrenic Greek patients.
Outcome Measures
| Outcome | Result | p-value |
|---|---|---|
| PRIMARY Summary of Schizophrenia |
1; 5; 9; 39; 0; 1 | — |
| PRIMARY Summary of Metabolic Risk Factors |
205; 245; 133; 64; 48; 48 | — |
| PRIMARY Summary of Most Frequently Used Concomitant Drug Treatments |
6; 11; 12; 24; 0; 0 | — |
| SECONDARY Number of Participants With Categorical Scores on Clinical Global Impression - Improvement (CGI-I) |
0; 1; 2; 12; 0; 1 | — |
| SECONDARY Number of Participants With Categorical Scores on Clinical Global Impression of Severity (CGI-S) |
0; 0; 1; 0; 0; 0 | — |
| SECONDARY Positive and Negative Syndrome Scale (PANSS) - Positive Subscale |
12.9; 14.4; 14.6; 16.6; 12.6; 10.2 | — |
| SECONDARY PANSS - Negative Subscale |
16.7; 16.1; 14.6; 14.7; 12.8; 14.1 | — |
| SECONDARY PANSS - Composite Subscale |
-3.8; -1.7; 0.0; 1.9; -0.2; -3.9 | — |
| SECONDARY Number of Participants Answering the Question "How Satisfied or Dissatisfied Are You With the Ability of the Medication to Prevent or Treat Your Condition?" |
0; 0; 0; 1; 0; 0 | — |
| SECONDARY Number of Participants Answering the Question "How Satisfied or Dissatisfied Are You With the Way the Medication Relieves Your Symptoms?" |
0; 0; 0; 1; 0; 0 | — |
| SECONDARY Number of Participants Answering the Question "How Satisfied or Dissatisfied Are You With the Amount of Time it Takes the Medication to Start Working?" |
0; 0; 0; 2; 0; 0 | — |
| SECONDARY Number of Participants Answering the Question "As a Result of Taking This Medication, do You Experience Any Side Effects at All?" |
3; 11; 13; 84; 1; 11 | — |
| SECONDARY Number of Participants Answering the Question "How Bothersome Are the Side Effects of the Medication You Take to Treat Your Condition?" |
0; 0; 0; 1; 0; 0 | — |
| SECONDARY Number of Participants Answering the Question "To What Extent do the Side Effects Interfere With Your Physical Health and Ability to Function (ie, Ability to Think Clearly, Stay Awake, Etc)?" |
0; 0; 1; 6; 0; 0 | — |
| SECONDARY Number of Participants Answering the Question "To What Extent do the Side Effects Interfere With Your Mental Function (ie, Ability to Think, Stay Awake, Etc)?" |
3; 11; 13; 84; 1; 0 | — |
| SECONDARY Number of Participants Answering the Question "To What Degree Have Medication Side Effects Affected Your Overall Satisfaction With the Medication?" |
0; 0; 1; 2; 0; 0 | — |
| SECONDARY Number of Participants Answering the Question "How Easy or Difficult is it to Use the Medication in Its Current Form?" |
0; 0; 0; 2; 0; 0 | — |
| SECONDARY Number of Participants Answering the Question "How Easy or Difficult is it to Plan When You Will Use the Medication Each Time?" |
0; 0; 0; 0; 0; 0 | — |
| SECONDARY Number of Participants Answering the Question "How Convenient or Inconvenient is it to Take the Medication as Instructed?" |
0; 0; 0; 1; 0; 0 | — |
| SECONDARY Number of Participants Answering the Question "Overall, How Confident Are You That Taking This Medication is a Good Thing?" |
0; 2; 2; 13; 0; 2 | — |
| SECONDARY Number of Participants Answering the Question "How Certain Are You That the Good Things About Your Medication Outweigh the Bad Things?" |
0; 1; 2; 15; 0; 3 | — |
| SECONDARY Number of Participants Answering the Question "Taking All Things Into Account, How Satisfied or Dissatisfied Are You With This Medication?" |
0; 0; 0; 2; 0; 0 | — |
| SECONDARY Percent Change From Baseline to Final Visit in Body Weight |
1.2; -0.2; -1.0; 0.1; -1.0 | — |
Eligibility Criteria
Inclusion Criteria
- Usual clinical practice of physician
Exclusion Criteria
- None
Data sourced from ClinicalTrials.gov (NCT00579670). Outcome figures and adverse-event rates are extracted automatically from the registry's posted results and are provided for clinician reference, not as a substitute for the primary publication. Informational only — not medical advice.